MR and CT of Brain's Cava

Abstract

The Cavum Septi Pellucidi (CSP), Cavum Vergae (CV) and Cavum Veli Interpositi, are anatomical variants located in the midline of the brain. It is important to identify these conditions to distinguish them from other entities that may require treatment. In this paper, our purpose is to describe MR and CT findings of CSP, CV and Cavum Veli Interpositi, explaining the differential diagnosis.

Incidental Findings and Normal Anatomical Variants on MRI of the Brain in Adults for Primary Headaches

“…Both are anatomical variants . The CSP, which is part of normal development, is the space between the two leaflets of the septum pellucidum, which has been reported as persisting in adults in 3‐60% of cases.…”

“…23 Cavum Septum Pellucidi (CSP) and Cavum Vergae (CV).-Both are anatomical variants. 24 The CSP, which is part of normal development, is the space between the two leaflets of the septum pellucidum, which has been reported as persisting in adults in 3-60% of cases. The CV is the continuation of the CSP posterior to a coronal plate through the columns of the fornix.…”

Brain MRI findings in aspartylglucosaminuria

“…In our study, 55% of AGU patients had mildly dilated CVI measuring more than 10 mm in width. CVI is usually considered an incidental finding, but an association with intellectual disability, epilepsy and autism has also been reported and large CVI may cause obstructive hydrocephalus [30,31]. None of the AGU patients in our study showed large CVI and no symptoms of obstructive hydrocephalus were noted.…”

“…CVI is a frequent imaging finding in infants and young children (up to 34%), but in most cases it closes in early childhood and the incidence in children over 2 years of age is 2-3%. In the adult population the incidence is reported to be between 5.5 to 7.2% [30]. In our study, 55% of AGU patients had mildly dilated CVI measuring more than 10 mm in width.…”

Common variants ofNRXN1, LRP1BandRORAare associated with increased ventricular volumes in psychosis - GWAS findings from the B-SNIP deep phenotyping study

“…The cavum septum pellucidum is a space between the two leaflets of the septum pellucidum that normally occludes in 85% of babies by age 6 months [40]; its persistence has been related to neurodevelopmental delay [41], and with SZ and BD [17,18,42,43], presumably because of a reduction of the limbic structures that surround it: the septal nuclei, fornix and hippocampal commissure. In our sample this quantitative phenotype measured in voxels by FreeSurfer was significantly different in cases vs. controls (ANOVA P=9.4E-05, Figure 2), with larger volumes for individuals with SZ than BP, which is consistent with findings from Shioiri et al [18].…”