Formation of edible oil-loaded beeswax microparticles using PGSS – Particles from Gas-Saturated Solutions

Aredo, Víctor; Bittencourt, Gabriela Marques; Pallone, Elíria Maria de Jesus Agnolon; Guimarães, Francisco; Oliveira, Alessandra Lopes de

doi:10.1016/j.supflu.2020.105106

Cited by 6 publications

(1 citation statement)

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“…124–126. Particle from gas‐saturated solutions (PGSS) stands out among other supercritical strategies since it for the foremost part does not require organic solvents. This procedure comprises the immersion of eatable liquid fats with SC‐CO 2 that are hence extended through a spout 127–129. Within the PGSS process, the polymer suspension and CO 2 is stacked into the high‐pressure cell, which is warmed and pressurized to SC‐CO 2 conditions to reach phase equilibrium.…”

Section: Introductionmentioning

confidence: 99%

Solubility, Extraction, and Nanoparticles Production in Supercritical Carbon Dioxide: A Mini‐Review

Sodeifian

Usefi

2022

ChemBioEng Reviews

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Supercritical carbon dioxide (SC‐CO2) is CO2 that is stored beyond its critical point of 7.4 MPa and 31.1 °C. Given the request for consumption of a green solvent for the environment, SC‐CO2 is widely utilized in chemical, food, and pharmaceutical industries. To design material and drug production processes using supercritical fluid (SCF) technology, knowledge of their solubility is important. Temperature and pressure are the main factors in the study of solubility. Solubility data are then evaluated using equation of state, semi‐empirical, and intelligence models to establish suitable correlations. SC‐CO2 is one of the most important materials used in SCFs to study solubility. Another application of SC‐CO2 is in the field of material extraction to reduce the consumption of organic solvents. Nanoparticles production in drug industry is another advantage of SC‐CO2. Micro and nanoparticles can be produced using SCF techniques. In this review, the applications of SC‐CO2 in drug solubility, extraction of valuable materials, and nanoparticles production for pharmaceutical processes are reported and discussed. Finally, the main challenges are explained.

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Section: Introductionmentioning

confidence: 99%