Fatty acid composition in two sea cucumber species, Holothuria scabra and Holothuria leucospilata from Qeshm Island (Persian Gulf)

Yahyavi, M; Afkhami, Majid; Javadi, Ali; Ehsanpour, Maryam; Khazaali, Aida; Khoshnood, Reza Jalili; Amin, Mansour

doi:10.5897/ajb11.3529

Cited by 10 publications

(5 citation statements)

References 19 publications

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“…11 Sea cucumbers contain substantial amounts of PUFAs, accounting for approximately 57% of total fatty acids, with EPA and DHA contributing 2.8−37.8 and 8.0−44.0%, respectively; additionally, around 44% of EPA and 3.9% of DHA were present in the form of phospholipids. 12,13 Although aquatic phospholipids hold significant developmental potential, technical limitations have restricted current research on phospholipids to primarily focuses on microalgae, krill, and a few fish species. Furthermore, there is a lack of comprehensive and efficient screening of phospholipid resources from aquatic products.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Marine organisms, including microalgae, krill, sea cucumbers, squid, fish, and their processing byproducts, are the primary sources of N-3 PL PUFAs . − For example, Falk et al analyzed the fatty acid profiles of phospholipids in Arctic and Antarctic krill and discovered that phospholipids comprised 26–30% EPA and 10–20% DHA . Sea cucumbers contain substantial amounts of PUFAs, accounting for approximately 57% of total fatty acids, with EPA and DHA contributing 2.8–37.8 and 8.0–44.0%, respectively; additionally, around 44% of EPA and 3.9% of DHA were present in the form of phospholipids. , Although aquatic phospholipids hold significant developmental potential, technical limitations have restricted current research on phospholipids to primarily focuses on microalgae, krill, and a few fish species. Furthermore, there is a lack of comprehensive and efficient screening of phospholipid resources from aquatic products.…”

Section: Introductionmentioning

confidence: 99%

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Comprehensive Screening for EPA/DHA-Structured Phospholipids in Aquatic Products by a Specific Precursor Ion Scanning-Based HILIC-MS/MS Method

Xue

Wang

et al. 2023

J. Agric. Food Chem.

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Comprehensive screening for functional substances from natural resources is always a hot research topic. Eicosapentaenoic acid-(EPA) and docosahexaenoic acid (DHA)-structured phospholipids (PL EPA/DHA ) have versatile cardiovascular benefits as well as superior bioavailability. Herein, the abundance of PL EPA/DHA in 16 aquatic products was specifically and selectively screened using a recently developed precursor ion scan-driven hydrophilic interaction chromatography−mass spectrometry (PreIS-HILIC/MS) method with the fatty acyl moieties of EPA (m/z 301.6) and DHA (m/z 327.6) locked. The aim focused on the characteristics and differences in the varieties and contents of EPA/DHA-structured phosphatidylcholine (PC EPA/DHA ) and EPA/ DHA-structured phosphatidylethanolamine (PE EPA/DHA ) molecular species. A total of 80 PL EPA/DHA molecules were identified in these natural sources, including 47 PC EPA/DHA and 33 PE EPA/DHA . After analysis, PC 16:0/20:5 and PC 16:0/22:6 are present in all aquatic products and at high levels. Antarctic krill was found to be the best resource of PL EPA/DHA in total (2574.69 μg•g −1 ), followed by mackerel (2330.11 μg•g −1 ), salmon (2109.91 μg•g −1 ), and Farrer's scallop (1883.59 μg•g −1 ), while abalone contained the lowest level of PL EPA/DHA (310.44 μg•g −1 ). Besides, sea cucumber and sea bass contained the highest contents of EPA-structured and DHAstructured ether phospholipids, respectively, which could be highly recommended as dietary sources of special functional phospholipids. Finally, the multiple discrepancies between the 16 aquatic products were revealed by multivariate statistical analysis. These findings improve the awareness of the composition and content of PL EPA/DHA contained in aquatic products, providing a reference for their integrated development.

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comprehensive Screening for EPA/DHA-Structured Phospholipids in Aquatic Products by a Specific Precursor Ion Scanning-Based HILIC-MS/MS Method

Xue

Wang

et al. 2023

J. Agric. Food Chem.

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“…Eels contain EPA and DHA as many as 1.15% and 5.16%, respectively (Kusharto et al, 2014). Omega 3, especially EPA and DHA in sea cucumbers, is 0.22 mg/mL (Yahyav, 2012). This amount is classified as high so that eels and sea cucumbers have potential activity as an anti-inflammatory.…”

Section: Introductionmentioning

confidence: 99%

Cox-2 inhibition activities of creams containing anguilla bicolor and sea cucumbers extract on croton oil induced inflammation in mice

et al. 2020

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“…Microscopically, the cytotoxic effect may be linked to the mutagenic action or genotoxic effect of the present active components of crude extracts that may have interfered with the normally nuclear process of the onion root tip cells. Holothurians are also a rich source of essential fatty acids, which include classes of long-chain polyunsaturated fatty acids (PUFA) like arachidonic, eicosapentaenoic and docosahexaenoic acids (Anisuzzaman et al, 2019) and the monounsaturated fatty (MUFA), namely gadoleic and cis-oleic acids (Yahyavi et al, 2012). Like docosahexaenoic acid, which was found to inhibit the growth of cancer cells, a long-chain saturated fatty acid called stearic acid from sea cucumber (Holothuria sp.)…”

Section: Other Sea Cucumber Species' Bioactive Compounds and Their Ge...mentioning

confidence: 99%

Mitodepressive and Genotoxic Potential of Crude Body Wall and Cuvierian Tubule Extracts of Mani-mani (Pearsonothuria graeffei Semper) on Root Meristems of Onion (Allium cepa L.)

Torres,

Malaya

2021

MJST

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The need to discover novel natural products has resulted in several explorations in the marine environment. The biological compounds from aquatic resources can boost effort on drug development and may promote species conservation. In this study, the mitodepressive and genotoxic properties of the extracts obtained from Pearsonothuria graeffei – a widely distributed and poorly explored sea cucumber species – were evaluated using the Allium test. The sea cucumber body wall and cuvierian tubule crude methanol, ethyl acetate and n-hexane extracts were found to have potential genotoxic properties at concentrations of 500, 1,000 and 1,500 μg mL-1. A significant (p < 0.05) growth inhibition in both length and the number of roots was exhibited at higher concentrations (1,000 and 1,500 μg mL-1) of the crude extracts similar to the control mutagen. The 1,000 μg mL-1 of cuvierian tubule methanol extract resulted in higher general toxicity in terms of root length inhibition than the control mutagen. A significantly lower mitotic index was exhibited in the crude body wall methanol extract at 500 μg mL-1 concentration. Also, a higher percent chromosomal aberration (p < 0.05) was observed in onions treated with all concentrations of crude body wall ethyl acetate and n-hexane extracts, and 500 μg mL-1 of the crude cuvierian tubule methanol and n-hexane extracts. In conclusion, the crude extracts of P. graeffei have mitodepressive and genotoxic properties, which are potential sources of bioactive compounds necessary for the development of treatment for some serious human diseases like cancer.

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Fatty acid composition in two sea cucumber species, Holothuria scabra and Holothuria leucospilata from Qeshm Island (Persian Gulf)

Cited by 10 publications

References 19 publications

Comprehensive Screening for EPA/DHA-Structured Phospholipids in Aquatic Products by a Specific Precursor Ion Scanning-Based HILIC-MS/MS Method

Comprehensive Screening for EPA/DHA-Structured Phospholipids in Aquatic Products by a Specific Precursor Ion Scanning-Based HILIC-MS/MS Method

Cox-2 inhibition activities of creams containing anguilla bicolor and sea cucumbers extract on croton oil induced inflammation in mice

Mitodepressive and Genotoxic Potential of Crude Body Wall and Cuvierian Tubule Extracts of Mani-mani (Pearsonothuria graeffei Semper) on Root Meristems of Onion (Allium cepa L.)

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