Cox-2 inhibition activities of creams containing anguilla bicolor and sea cucumbers extract on croton oil induced inflammation in mice

Sasongko, Heru; Qanit, Waliyyin Razan; W.S, Raka Sukmabayu; S.P.Kristyawan, Agung Putu; Sugihartini, Nining; Kundarto, Wisnu; Ermawati, Dian Eka

doi:10.12928/pharmaciana.v10i3.14823

Cited by 1 publication

(3 citation statements)

References 19 publications

(25 reference statements)

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“…In addition to the BALB/C mice model Moradi et al (2020) attempted to evaluate the anti-inflammatory mechanisms of methanolic extract of Persian Gulf sea cucumber (H. leucospilota) on rats. Similar to Sasongko et al (2020) observation H. leucospilota treated group had significantly low Hind paw edema compared to the carrageenan-induced rat group (Moradi et al, 2020). In addition, Zhang et al (2021) also report the anti-inflammatory properties A. japonicus hydrolysates against CuSO 4 -induced neuromast damage in a zebrafish model.…”

Section: Anti-inflammatory Activities Reported From Sea Cucumberssupporting

confidence: 65%

“…However, according to the authors sterol sulfate administrated mice had decreased expression levels of TNF-α, monocyte chemoattractant protein 1, and IL-6 (Zhang et al, 2020). In addition, cyclooxygenase-2 (COX2) inhibition activities of creams containing Anguilla bicolor (Eel) and sea cucumber H. leucospilota extract on croton oil-induced inflammation in BALB/C mice were also reported by Sasongko et al (2020). According to the authors, H. leucospilota treatment was found to decrease inflammatory cell number, epidermal thickness, and decreasing number of cells expressing COX2 in cotton oilinduced BALB/C mice compared to the control (Sasongko et al, 2020).…”

Section: Anti-inflammatory Activities Reported From Sea Cucumbersmentioning

confidence: 92%

“…In addition, cyclooxygenase-2 (COX2) inhibition activities of creams containing Anguilla bicolor (Eel) and sea cucumber H. leucospilota extract on croton oil-induced inflammation in BALB/C mice were also reported by Sasongko et al (2020). According to the authors, H. leucospilota treatment was found to decrease inflammatory cell number, epidermal thickness, and decreasing number of cells expressing COX2 in cotton oilinduced BALB/C mice compared to the control (Sasongko et al, 2020). In addition to the BALB/C mice model Moradi et al (2020) attempted to evaluate the anti-inflammatory mechanisms of methanolic extract of Persian Gulf sea cucumber (H. leucospilota) on rats.…”

Section: Anti-inflammatory Activities Reported From Sea Cucumbersmentioning

confidence: 99%

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Bioactive secondary metabolites in sea cucumbers and their potential to use in the functional food industry

Sanjeewa¹,

Herath²

2023

Fish Aquat Sci

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The bioactive secondary metabolites produced by sea cucumbers are very diverse with differences in composition, linkages, molecular weight, and various functional properties. Due to their physicochemical properties, these bioactive molecules in sea cucumbers have found applications in various market segments such as functional foods and cosmetics. Sea cucumber side dishes are a prominent food item in traditional cuisine in East Asian countries such as South Korea, China, and Japan. In addition, many studies have reported that the consumption of sea cucumbers can reduce the risk of cardiovascular disease, the pathogenesis of cancer cells, chronic inflammatory diseases, etc. In particular, many studies have recently reported the potential of sea cucumbers to develop functional products to reduce inflammation, oxidative stress, diabetes, and cancer. Additionally, these bioactive properties associated with sea cucumbers make them ideal compounds for use as functional ingredients in functional food products. However, no report has yet reviewed the properties of sea cucumbers related to functional foods. Therefore, in this review, the primary focus is given to collecting published scientific data (from 2019 to 2023) on the bioactive properties of sea cucumbers relevant to the functional food industry.

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Section: Anti-inflammatory Activities Reported From Sea Cucumberssupporting

confidence: 65%