“…The synthetic In 2018, Zhu and coworkers demonstrated palladium catalyzed/norbornene mediated dehydrogenative annulation strategy for the synthesis of 6-fluoroalkyl-phenanthridines 66 from aryl iodides 1 and fluorinated imidoyl chlorides 65 (Scheme 11). [19] Optimized reaction condition was realized with Pd(OAc) 2 (10 mol %) as the catalyst, P(4-F-C 6 H 4 ) 3 (20 mol %) as the ligand, norbornene (1 equiv) as the co-catalyst and K 3 PO 4 (4 equiv) as a base in toluene at 100°C for 12 h. Notably, P(4-F-C 6 H 4 ) 3 ligand and K 3 PO 4 base were essential for this transformation to achieve better yields of the required products. Substrate scope studies revealed that various functional groups such as isopropyl, methoxyl, fluoro, chloro, trifluoromethyl, trifluoromethoxyl and phenyl present at ortho position of aryl iodides were well tolerated provided the corresponding annulated products in moderate to excellent yields.…”