In the review, recent advances in the synthetic applications of trifluoroacetimidoyl halides have been summarized.

A general and expeditious approach for the copper mediated synthesis of multi‐functionalized dihydropyrazoles from N‐sulfonylhydrazones and sulfoxonium ylides has been achieved under aerobic oxidative conditions. The formal [4+1] cycloaddition reaction exhibits many notable features and can be easily scaled up to gram scale.

A metal-free approach for the synthesis of 5-trifluoromethyl-1,2,4-triazoles from trifluoroacetimidoyl chlorides and hydrazones has been achieved under aerobic oxidative conditions. The reaction proceeds through a cascade base-promoted intermolecular CÀ N bond formation and iodinemediated intramolecular CÀ N bond oxidative coupling sequence. The protocol features broad substrate scope and can be scaled up to gram scale.

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