Electropolymerization of Ni–LD metallopolymers on gold nanoparticles enriched multi-walled carbon nanotubes as nano-structure electrocatalyst for efficient voltammetric sertraline detection in human serum

Electrochemical determination of sertraline in pharmaceutical formulation and serum using a gold electrode in a pH 8.4 bicarbonate solution

“…Table 2 illustrates the obtained values of several important analytical parameters, such as linear range, LOD, LOQ, for the determination of sertraline that can be found in earlier reported papers. Comparing the obtained results on the Au electrode to previously published results presented in Table 2, concerning the electrochemical behaviour of sertraline, it can be concluded that an extension of the linear concentration range was accomplished [6][7][8][9][10]. The inclusion complexes of sertraline with HPβCD demonstrated a new electrochemical strategy for increasing the electrode's sensitivity in its quantitative determination.…”

“…The inclusion complexes of sertraline with HPβCD demonstrated a new electrochemical strategy for increasing the electrode's sensitivity in its quantitative determination. In addition, the obtained values of LOD and LOQ for the inclusion complex of the sertraline with HPβCD are comparable [10,11,38] or more than one order of magnitude higher than the published [6][7][8] as can be seen in Table 2. The evaluated parameters indicated a significant electrochemical response and possibility for analytical use.…”

“…A rutin-modified GCE demonstrated the catalytic capability for the oxidation of sertraline, whereby the anodic current linearly related to the drug concentration in the range from 3.0 to 90.0 μM [9]. Shoja et al described an innovative strategy for the determination of sertraline where nano-structured Ni(II)-levodopa film was electropolymerized on a GCE which was previously modified by gold nanoparticle-enriched multi-walled carbon nanotubes in an alkaline solution [10]. Namely, this nanostructure film was effective for the electrocatalytic oxidation of the drug and differential pulse voltammetry (DPV) was used for its determination in the range from 0.05 to 5.5 mM.…”

La2O3/Co3O4 nanocomposite modified screen printed electrode for voltammetric determination of sertraline

“…Furthermore, current researches have showed that selective 506 MOHAMMADI et al serotonin reuptake inhibitors such as sertraline interpenetrate the cell membrane are associated with a high risk of expanding cancer. 5 Accordingly, the precise determination of component amounts of sertraline biological specimens, such as plasma, blood and urine is necessary. The development of robust analytical methods that can easily detect pharmaceutical contaminants is challenging.…”

Glutathione‐stabilized Fe3O4 nanoparticles as the sorbent for magnetic solid‐phase extraction of diazepam and sertraline from urine samples through quantitation via high‐performance liquid chromatography

“…Hence, the preparation, characterization, and application of glutathione-coated magnetic nanoparticles were reported as a novel magnetic adsorbent for the extraction of two selected drugs including diazepam and sertraline (as the model analytes) from different types of urine samples. Sertraline, with the IUPAC name of cis-1S, 4S-N-methyl-4-(3, 4-dichlorophenyl)−1, 2, 3, 4-tetrahydro −1-naphthalenaminehydrochloride, is an anti-depression drug that is one of the most commonly-used drugs to treat depression due to having fewer side effects; however, recent studies have shown that selective serotonin reuptake inhibitors (SSRI) such as sertraline, infiltrate the cell membrane and greatly increase the risk of developing cancer [15]. Therefore, accurate assay of sertraline and its metabolites in biological samples, such as blood, plasma and urine is necessary.…”