<p style="margin: 0in 0in 0pt; text-align: justify; line-height: 200%; unicode-bidi: embed; direction: ltr;"><span lang="EN-US">Electrochemical characteristics of carvacrol were investigated on a screen-printed electrode (SPE) modified with La<sub>2</sub>O<sub>3</sub>/Co<sub>3</sub>O<sub>4</sub> nanocomposite by using voltammetric techniques, which displayed a well-defined peak for sensitive carvacrol determination in phosphate buffer solution (PBS) at pH 7.0. La<sub>2</sub>O<sub>3</sub>/Co<sub>3</sub>O<sub>4</sub> nanoparticles demonstrated suitable catalytic activity for carvacrol determination by differential pulse voltammetry (DPV) technique. Besides, determination of carvacrol in a real samples was recognized in the light of electrochemical findings and a validated voltammetric technique for quantitative analysis of carvacrol in a real formulation was proposed. The DPV peak currents were found to be linear in the concentration range of 10.0 to 800.0 μM. The limit of detection (LOD) was found to be 1.0 μM.</span></p>
La 2 O 3 /Co 3 O 4 nanocomposite was synthesized and then used for the modification of screen-printed electrode (SPE) prior to the electrochemical determination of sertraline. A significant increment in peak current response was observed and peak potential also shifted towards less positive potentials showing the facilitated oxidation procedure at surface of modified SPE (La 2 O 3 / /Co 3 O 4 /SPE). The quantitative determination of sertraline was carried out by using different pulse voltammetry and the anodic peak current was found to increase with increasing sertraline concentration in the linear range of 5.0-400.0 µM with limit of detection as 1.0 μM. The prepared La 2 O 3 /Co 3 O 4 /SPE has been successfully used for detecting sertraline in sertraline tablet and urine samples with excellent recoveries.
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