Effects of training on resting plasma levels of homocysteine and C-reactive protein in competitive male and female wrestlers

Abstract

SummaryStudy aim: To assess the effects of training on resting plasma levels of homocysteine (Hcy), C-reactive protein (CRP), folic acid, and on the activity of creatine kinase (CK) in competitive male and female wrestlers. Material and methods: Polish elite wrestlers, male MW; n = 11) and female (FW; n = 11), as well as corresponding numbers of untrained, control subjects (MC and FC, respectively), participated in the study. Blood for assays was withdrawn from the antecubital vein in the morning, in pre-prandial state. Homocysteine (Hcy), C-reactive protein (CRP), folic acid and creatine kinase (CK) activity were assayed in plasma.Results: Mean concentrations of Hcy and CRP were in the control groups significantly higher and those of folic acid -lower than in the respective groups of wrestlers. Folic acid levels were negatively correlated with Hcy, especially in wrestlers (r = -0.540; p<0.01). Mean CK activity was significantly (p<0.001) higher in male wrestlers than in male controls or female subjects. No significant correlation between CK and CRP was found. Conclusions: Strength-speed training practiced by elite wrestlers, associated with significantly lower values of Hcy and CRP in them compared with the untrained subjects, may reduce the risk of cardiovascular diseases at later age, like in case of endurance training.

Effects of training versus short exercise session on homocysteine levels in women with different body mass

“…Our study also suggests that a 9-month health training program significantly decreased homocysteine levels in the blood, compared to a single exercise of intensity above the anaerobic threshold. Similar observations were noted by other authors who claimed that physically active people have lower levels of homocysteine compared with those who do not train [20,21,28,49]. these observations may demonstrate that regular aerobic training regulates homocysteine metabolism in the blood, which could be used in the prevention and treatment of diseases caused by hypokinesis.…”

“…the apparent association between Hc and cardiovascular diseases [1,4,9], and the possibility of regulating Hc synthesis through vitamin B 6 , vitamin B 12 and folic acid supply and regular physical exercise support taking preventive measures [16]. It is also important as elevated Hc levels correlate with insulin resistance [17,18], markers of oxidative stress [19,20], and inflammatory markers [21], which coexist with obesity and diabetes, and can be reduced through regular physical exercise.…”

The Effect of Physical Activity on Cardiovascular Markers

“…Hubner-Wozniak and Ochocki, in a research conducted on male and female wrestlers, reported that strength and speed trainings in elite wrestlers significantly reduced the levels of CRP and homocysteine HCY (24). Parsian et al investigated the effect of strength training on serum Creactive protein and plasma fibrinogen levels in untrained young men, and showed that strength training did not significantly reduce serum CRP in the untrained young men (25).…”

Diurnal hormonal responses in exercise and sports medicine research: range effect adjustments

“…post-exercise vs. pre-exercise values), or as a delta scores (post-exercise -pre-exercise, etc.). Such transformation methods are a common approach and are used in an attempt to deal with the inherent variability found in many human-based endocrinological measurements [1,6,9,11]. …”

“…In other words, hormonal responses are not infinitely continuous and there is a limit to the normal responses of a hormone at rest or in response to a stimulus within healthy individuals. Research suggests this type of limitation in both the normal basal range of responses due to rhythmical oscillations or in response to a stimulus is found for the blood values of certain circulating hormones (e.g., growth hormone, prolactin, testosterone) [1,6,8,9,11]. …”