EFEKTIVITAS EKSTRAK DAUN MENGKUDU (Morinda citrifolia L.) DAN DAUN SIRIH MERAH (Piper crocatum Ruiz &amp; Pav) TERHADAP ZONA HAMBAT PERTUMBUHAN Staphylococcus aureus

Afiff, F.E; Amilah, Susie

doi:10.36456/stigma.vol10.no1.a635

Cited by 6 publications

(8 citation statements)

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“…The phytochemical properties of M. citrifolia fruit extract contained flavonoids (such as flavones, flavonols, anthocyanidins, flavanols, flavanones, flavanonols, aurones, furan chromones, isoflavones, isoflavonones, biflavones, xanthones, chaocones, and dihydrochalcones), tannins, and steroids (such as stigma sterol, daucosterol, and β-sitosterol), similar to previous reports (Nagalingam et al 2012;Afiff and Amilah 2017;Youn and Chang 2017;Sogandi and Nilasari 2019;Yee 2019;Ayunda et al 2020). This study showed that the major components of M. citrifolia fruit extract were 2-fluorobenzoic acid, eucalyptol, 2chloroaniline-5-sulfonic acid, hexadecamethyl octasiloxane, and tetrapropyl stannane.…”

Section: Discussionsupporting

confidence: 89%

Chemical composition and antifungal activity of Morinda Citrifolia fruit extract

et al. 2023

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Noni (Morinda citrifolia) fruit is a well-known plant used as a traditional medicine for preventing some diseases because of its abundance in chemical compounds. This research aimed to determine the phytochemical concentration, chemical composition, and antifungal activity of M. citrifolia fruit extract. M. citrifolia fruit was extracted with methanol and then distilled water for the partition extract. Subsequently, the extract was fractionated using various nonpolar to polar solutions, such as; chloroform, ethyl acetate, water, 2-propanol, and methanol fractions. Each fraction was evaporated until the dry extract was released. Additionally, the photochemical concentration of the M. citrifolia fruit extract was quantitatively determined using a UV-visible spectrophotometer. The chemical composition of the M. citrifolia fruit extract of each fraction was identified using gas chromatography-mass spectrometry (GC-MS). Then, the antifungal activity of M.citrifolia fruit extract against C. albicans and C. krusei was determined using the disc diffusion method. The results showed that the phytochemical concentration of the M. citrifolia fruit extract was 1970.25 ppm flavonoids, 35.61 ppm tannins, and 148.62 ppm steroids. 2-Fluorobenzoic acid, eucalyptol, 2-chloroaniline-5-sulfonic acid, hexa-decamethyl octasiloxane, and tetra-propyl stannane were found to be the major components of M. citrifolia fruit extract. According to the research, M. citrifolia fruit extract showed antifungal activity against C. albicans and C. krusei in all tested fractions. The maximum inhibition zone of C. albicans was 14.0 ± 1.00 mm in the 2-propanol fraction, while that of C. krusei was 11.7 ± 0.58 mm in the methanol fraction.

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Section: Discussionsupporting

confidence: 89%

Chemical composition and antifungal activity of Morinda Citrifolia fruit extract

et al. 2023

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“…Tumbuhan yang dapat digunakan sebagai antibakteri salah satunya adalah daun mengkudu. Mengkudu memiliki kandungan kimia seperti saponin, alkaloid, tanin, flavonoid, triterpenoid, antrakuinon, karoten, zat besi, zat kapur, senyawa moridin, aligerin-d-methyleter, xeronin, soranyideal, proxeronin, antioksidan, vitamin C, vitamin aA, askorbin, moridon, protein, lemak, kalori, niamin, karbohidrat, riboflavin, thiamin, mineral (kalsium, kalium, zat besi, natrium) [6,7].…”

Section: Pendahuluanunclassified

Uji Aktivitas Antibakteri Sediaan Sabun Cair Ekstrak Daun Mengkudu (Morinda citrifolia L.) Terhadap Staphylococcus aureus

Noviyanto

Nuriyah

Hadi

2020

JSSCR

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The bacteria Staphylococcus aureus are round bacteria that are shaped like a cocci, and are Gram-positive. These bacteria can be found on the skin, genitals, nasal cavity, mouth and around the anus. One of the pharmaceutical products that can maintain skin health and protect the skin is soap. The leaves of noni (M. citrifolia L.) contain various compounds such as flavonoids, tannins, saponins, alkaloids, and triterpenoids which are capable of being antibacterial. This study aims to make a liquid soap formulation from M. citrifolia L. leaf extract and its activity as an antibacterial to S aureus. The leaves of M. citrifolia L. were extracted using 96% ethanol solvent by maceration method until a thick extract was obtained. Soap formulations are made with a concentration of 20% 40% and 60%. Evaluation of soap quality includes organoleptic test, high foam test and pH test. The method of antibacterial testing is carried out in vitro by means of well diffusion. The results on the quality test of the liquid soap formulation showed that the pH and height of the foam had good results and had met the SNI 1996 Standards. From the results showed that formulation III with an extract content of 60% had a large antimicrobial activity with a value of 16.83 mm which was categorized as strong. In positive control (Dettol) 60% antimicrobial activity showed a value of 14.83 mm. The results of statistical tests were carried out by One-Way ANOVA analysis followed by LSD analysis Post hoc, liquid soap extract of M. citrifolia L. had greater antimicrobial potential than the positive control (Dettol).

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“…The activity of these compounds can damage the cell membrane or cell wall of bacteria. These compounds are mostly contained in the red leaves, but under certain conditions red betel leaves can change color (Afiff & Amilah, 2017). Leaves that are initially red at the bottom will change color to green and the silvery pattern will disappear (Rachmawaty et al, 2018) Staphylococcus epidermidis is a normal flora on the skin and is not pathogenic, but if there is a change in skin condition, the bacteria can become invasive (Lutpiatina, 2017).…”

Section: Introductionmentioning

confidence: 99%

Potential Anti-Bacterial Extract of Red Belt (Piper Crocatum Ruiz & Pav.) Against Staphylococcus Epidermidis

Sawitri

Mahmuda

2022

KESANS

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Introduction: Red betel leaf is a plant native to Indonesia which is used as an antiseptic, anti-cancer, and infection treatment. The ethanol content of red betel leaf extract is known to have antibacterial activity. Among them there are alkaloids, flavonoids, essential oils, tannins, and saponins. Objective: to determine the potential of red betel leaf extract (Piper crocatum Ruiz & Pav.) in inhibiting the growth of Staphylococcus epidermidis bacteria. Methods: Staphylococcus epidermidis bacteria were divided into 5 groups, PEG 5% as negative control, clindamycin 30µg/disk as positive control, extract 20%, 40%, 80% as treatment group. Measuring the zone of inhibition using a ruler. Result: Staphylococcus epidermidis inhibition zone was formed at concentrations of 20%, 40%, 80%. Kruskal Wallis analysis showed significant results of p = 0.000 for bacteria. Conclusion: Red betel leaf extract (Piper crocatum Ruiz & Pav.) has significant antibacterial activity against Staphylococcus epidermidis. The higher the concentration, the larger the diameter of the inhibition zone.

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EFEKTIVITAS EKSTRAK DAUN MENGKUDU (Morinda citrifolia L.) DAN DAUN SIRIH MERAH (Piper crocatum Ruiz & Pav) TERHADAP ZONA HAMBAT PERTUMBUHAN Staphylococcus aureus

Cited by 6 publications

References 0 publications

Chemical composition and antifungal activity of Morinda Citrifolia fruit extract

Chemical composition and antifungal activity of Morinda Citrifolia fruit extract

Uji Aktivitas Antibakteri Sediaan Sabun Cair Ekstrak Daun Mengkudu (Morinda citrifolia L.) Terhadap Staphylococcus aureus

Potential Anti-Bacterial Extract of Red Belt (Piper Crocatum Ruiz & Pav.) Against Staphylococcus Epidermidis

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