Development of Biosensors for the Detection of Hydrogen Peroxide

Giannoudi, L.; Piletska, Elena; Piletsky, Sergey A.

doi:10.1007/978-0-387-36672-2_16

Cited by 7 publications

(4 citation statements)

References 77 publications

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“…Another μPAD was designed for simultaneous detection of uric acid and glucose based on peroxidase mimicking platinum nanoparticles (Pt NPs) [ 443 ]. Hydrogen peroxide is an important analyte itself and a prominent product or substrate of catalyzed oxidation reactions [ 444 ]. Hence, various microfluidic biosensors utilizing nanozymes including Au@PtNP/GO [ 445 ], graphene oxide-gold [ 446 ], and cerium oxide nanosheets (NSs) [ 444 , 447 ] were developed for H202 measurement.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

“…Hydrogen peroxide is an important analyte itself and a prominent product or substrate of catalyzed oxidation reactions [ 444 ]. Hence, various microfluidic biosensors utilizing nanozymes including Au@PtNP/GO [ 445 ], graphene oxide-gold [ 446 ], and cerium oxide nanosheets (NSs) [ 444 , 447 ] were developed for H202 measurement. Nanozymes are exploited for point-of-care (POC) cancer diagnosis as well [ 442 , 448 , 449 ].…”

Section: Biomedical Applicationsmentioning

confidence: 99%

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Biomedical Applications of Microfluidic Devices: A Review

et al. 2022

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Both passive and active microfluidic chips are used in many biomedical and chemical applications to support fluid mixing, particle manipulations, and signal detection. Passive microfluidic devices are geometry-dependent, and their uses are rather limited. Active microfluidic devices include sensors or detectors that transduce chemical, biological, and physical changes into electrical or optical signals. Also, they are transduction devices that detect biological and chemical changes in biomedical applications, and they are highly versatile microfluidic tools for disease diagnosis and organ modeling. This review provides a comprehensive overview of the significant advances that have been made in the development of microfluidics devices. We will discuss the function of microfluidic devices as micromixers or as sorters of cells and substances (e.g., microfiltration, flow or displacement, and trapping). Microfluidic devices are fabricated using a range of techniques, including molding, etching, three-dimensional printing, and nanofabrication. Their broad utility lies in the detection of diagnostic biomarkers and organ-on-chip approaches that permit disease modeling in cancer, as well as uses in neurological, cardiovascular, hepatic, and pulmonary diseases. Biosensor applications allow for point-of-care testing, using assays based on enzymes, nanozymes, antibodies, or nucleic acids (DNA or RNA). An anticipated development in the field includes the optimization of techniques for the fabrication of microfluidic devices using biocompatible materials. These developments will increase biomedical versatility, reduce diagnostic costs, and accelerate diagnosis time of microfluidics technology.

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Section: Biomedical Applicationsmentioning

confidence: 99%

Section: Biomedical Applicationsmentioning

confidence: 99%

Biomedical Applications of Microfluidic Devices: A Review

et al. 2022

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“…A number of electroactive chemical species can interfere since they are oxidised within the same potential range. Several electrochemical sensors and biosensors have been described to minimize the interferences (Giannoudi et al, 2006) by modifying the transducers particularly by Prussian blue and its analogous (Karyakin, 2001;Ricci & Palleschi, 2005), carbon nanotubes (Wang, 2005;Zagal et al, 2009) and peroxidase enzymes. The latter are based on electron transfer reactions between the enzyme and the working electrode either directly (Ferapontova, 2004) or through redox mediators (Ruzgas et al, 1996).…”

Section: Disposable Amperometric Peroxidase Mediated Biosensormentioning

confidence: 99%

“No calibration” type sensor in routine amperometric bio-sensing: An example of a disposable hydrogen peroxide biosensor

Creanga¹,

Şerban²,

Pittson³

et al. 2011

Biosensors - Emerging Materials and Applications

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“…It is generally detected by classical approaches as titration analysis, batch injection analysis (BIA) coupled to amperometric detectors (Silva et al 2012), or by colorimetric assays (Costa et al 2020). To reduce the time and costs of the analysis, enzymatic biosensors and non-enzymatic sensors were J o u r n a l P r e -p r o o f optimised (Giannoudi et al 2006;Shamkhalichenar et al 2020, Hou et al, 2019. Particularly, the nonenzymatic sensors were developed mainly to overcome the thermal and chemical instability suffered by enzymes.…”

Section: Introductionmentioning

confidence: 99%