Determination of Antiradical Activity, Total Phenolic, and Total Flavonoid Contents of Extracts and Fractions of Langsat (Lansium domesticum Coor.) Seeds

Yamin, Yamin; Ruslin, Ruslin; Sabarudin, Sabarudin; Sida, Nurramadhani A; Kasmawati, Henny; Diman, La Ode Muhammad

doi:10.33084/bjop.v3i4.1500

Cited by 8 publications

(5 citation statements)

References 29 publications

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“…Moreover, the EtOAc fraction of the seeds exhibited a strong antiradical potential (IC 50 8.938 µg/mL) than water fraction, n-hexane fraction, and methanol extract (IC 50 13.898, 11.012, and 14.624 µg/mL, respectively) in comparison to vitamin C (IC 50 4.721 µg/mL). This effect was referred to its high phenolic and flavonoid contents (58.25 mg GAE/g and 75.123 mg QE/g, respectively) [ 119 ].…”

Section: Biological Activities Of L Domesticum Ext...mentioning

confidence: 99%

Lansium domesticum—A Fruit with Multi-Benefits: Traditional Uses, Phytochemicals, Nutritional Value, and Bioactivities

2022

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Lansium domesticum (Langsat, Meliaceae) is a tropical fruit mainly found in Southeast Asian countries, particularly in Thailand, Malaysia, Indonesia, and the Philippines. Traditionally, it is utilized as a folk treatment for eye inflammation, ulcers, diarrhea, dysentery, fever, spasms, flatulence, worms, insect bites, scorpion stings, and malaria. Additionally, it is utilized as a mosquito repellent, skin moisturizer and whitening agent. Pharmacological research showed that the plant has a wide array of bioactivities, including antimalarial, antifeedant, anti-aging, wound healing, antioxidant, cytotoxic, analgesic, antibacterial, antimutagenic, insecticidal, and larvicidal. The most commonly described activities were attributed to the presence of terpenoids and phenolics. Further, some studies reported the preparation of nanoparticles and pharmaceutical formulations from the plant. This review highlights the potential of L. domesticum as herbal medicine. It provides an overview about the reported data on L. domesticum from 1931 to November 2021, including nutritional value, traditional uses, phytoconstituents, and bioactivities, as well as nanoparticles and pharmaceutical formulations.

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Section: Biological Activities Of L Domesticum Ext...mentioning

confidence: 99%

Lansium domesticum—A Fruit with Multi-Benefits: Traditional Uses, Phytochemicals, Nutritional Value, and Bioactivities

2022

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“…FlavonoidsAs much as 0.1 g of the thick extract of the rhizome of L. articulata was dissolved in 1 mL of ethanol.The solution was then added with Mg powder and a drop of concentrated HCl. A change in color to orange, red, or yellow indicated positive results18 .e. TanninsAs much as 0.1 g of the thick extract of the rhizome of L. articulata was dissolved in 1 mL of ethanol.The test solution was added with 1 mL of 10% gelatin.…”

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confidence: 99%

Standardization of Simplicia and Ethanol Extract of Purun Danau (Lepironia articulata (Retz.) Domin) Rhizome

et al. 2021

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Purun Danau (Lepironia articulata (Retz.) Domin) has been shown to have antimalarial and antioxidant activity. This study aimed to standardize simplicia and extract of L. articulata by determining the value of its specific and non-specific parameters. A sampling of L. articulata rhizome was carried out in Guntung Manggis, Haur Gading, and Halat. The standardization method used was based on the Indonesian Herbal Pharmacopoeia and the General Standard Parameter of Extract. The organoleptic observations showed that L. articulata simplicia was reddish-brown in color, chelated taste, and had a specific odor. Microscopic observation showed parts of this plant: epidermis, cortex, endodermis, parenchyma, bundle vessels, and scalariform vessels. Ethanol-soluble extract content was 10.00-12.66%, water-soluble extract content 8.03-10.87%, drying shrinkage 7.10-7.33%, total ash content 2.03-2.52%, acid-insoluble ash 0.33-0.42%, Pb content 5.698-9.989 ppm, Cd content 0.300-0.500 ppm, Hg content 0.070-0.090 ppm. Ethanol extract of L. articulata rhizome contained alkaloids, flavonoids, tannins, glycosides, and saponins. The yield obtained was 8.05-11.23%, total ash content was 1.58-1.67%, acid-insoluble ash was 0.23-0.33%, and water content was 7.10-8.50%. Standardization of simplicia and ethanol extract of L. articulata rhizome has met the criteria.

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“…Using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) technique, the antiradical potential of L. domesticum seeds extract and fractions was evaluated. In comparison to the n-hexane fraction, water fraction, and methanol extract, the ethyl acetate fraction provided a significant contribution as an antioxidant, with IC 50 values of 8.938 ± 0.031, 11.012 ± 0.094, 13.898 ± 0.81, and 14.624 ± 0.456 µg/mL, respectively [42]. L. domesticum Corr.…”

Section: Antioxidant Activitymentioning

confidence: 96%

“…to cure digestive disorders and malaria [42]. Now, the activities of this plant have been more explored.…”

Section: Pharmacological Activity Of L Domesticum Corrmentioning

confidence: 99%

A Review on Phytochemicals and Pharmacological Activities as Ethnomedicinal Uses of Duku (Lansium domesticum Corr.)

Lubis

Hasibuan

Syahputra

et al. 2022

Open Access Maced J Med Sci

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BACKGROUND: Lansium domesticum Corr. is a plant that is easily found in Indonesia. People use the fruit to be sold because it has a good taste. Some people use other parts of the plant as medicine. This plant has great potential to be developed as a standardized traditional medicine. AIM: This article review aims to collect information on secondary metabolite compounds from L. domesticum Corr. and its pharmacological activities as antioxidants, antibacterials, and cytotoxics. METHODS: Data on L. domesticum Corr. or duku were sought and collected for this miniature estimate and perspective. We use the major search engines with specific keywords such as L. domesticum Corr.; duku; morphology; pharmacological effects; secondary metabolites; in vitro; and in vivo. RESULTS: This review shows that L. domesticum Corr. have antioxidant, antibacterial, and cytotoxic activity of various compounds based on the test method used. CONCLUSIONS: Some parts of L. domesticum Corr. such as leaves, fruit, fruit skins, and seeds contain secondary metabolite compounds. The most common type of active compound is the steroid/terpenoid group. These compounds are responsible for their pharmacological activities such as antioxidants, antibacterials, and cytotoxics.

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Determination of Antiradical Activity, Total Phenolic, and Total Flavonoid Contents of Extracts and Fractions of Langsat (Lansium domesticum Coor.) Seeds

Cited by 8 publications

References 29 publications

Lansium domesticum—A Fruit with Multi-Benefits: Traditional Uses, Phytochemicals, Nutritional Value, and Bioactivities

Lansium domesticum—A Fruit with Multi-Benefits: Traditional Uses, Phytochemicals, Nutritional Value, and Bioactivities

Standardization of Simplicia and Ethanol Extract of Purun Danau (Lepironia articulata (Retz.) Domin) Rhizome

A Review on Phytochemicals and Pharmacological Activities as Ethnomedicinal Uses of Duku (Lansium domesticum Corr.)

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