Desigualdade social no adoecimento e morte por câncer de boca e orofaríngeo no município de São Paulo, Brasil: 1997 a 2008

Ferreira, Maria Ângela Fernandes; Gomes, Murilo Novaes; Michels, Fernanda Alessandra Silva; Dantas, Aldo; Latorre, Maria do Rosário Dias de Oliveira

doi:10.1590/s0102-311x2012000900006

Cited by 11 publications

(9 citation statements)

References 24 publications

(25 reference statements)

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“…It was also observed, similar to the present study, that patients with low education and high immunoexpression for TNF-α showed a worse survival rate, in addition to greater staging and use of surgery associated with radiotherapy and chemotherapy as a treatment of choice (Krishnan et al, 2014). In previous studies, patients with stage III and IV tumours expressed more TNF-α; in the researchers' country, patients with advanced disease stage are patients with a low level of education (Ferreira et al, 2012;Dantas et al, 2016).…”

Section: Discussionsupporting

confidence: 88%

Role of Inflammatory Markers in Prognosis of Oral Squamous Cell Carcinoma

Dantas

Silva

Verde

et al. 2019

Asian Pac J Cancer Prev

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Background: This estudie evaluated the immunostaining of cytokines in oral carcinoma, in tissue of margin of surgical resecate (MSR) and metastatic lymph nodes, as well as their role in patient prognosis. Methods: A retrospective study was carried out in patients with oral squamous cell carcinomas, and sociodemographic and clinical-pathological data were evaluated. In addition, surgical site analysis of the patients was conducted by immunohistochemistry, using a tissue microarray for inflammatory (Tumor Necrosis Factor-alpha, Interleukin-1beta, Interleukin-6, interleukin-10), transcription NF-kappa B and CD68 markers. Immunoexpression was assessed qualitatively and quantitatively using ImageJ software, and data were correlated with the prognostic factors and patient survival rates. Results: There was a greater immunoexpression of inflammatory and CD68 cytokines in primary tumour and lymph node metastasis than in MSR. In a multinomial logistic regression model, patients with low education (p = 0.041) and a high histoscore for TNF-α (p = 0.021) showed a survival rate of 15.64 (95% CI = 1.13-217.24) and 6.81 (95% CI = 1.02-105.96). Conclusion: Therefore, despite there is an increased immunoexpression of cytokines in the primary tumour, only TNF-α was the inflammatory cytokine that influenced the survival of patients with oral cancer.

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Section: Discussionsupporting

confidence: 88%

Role of Inflammatory Markers in Prognosis of Oral Squamous Cell Carcinoma

Dantas

Silva

Verde

et al. 2019

Asian Pac J Cancer Prev

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“…Studies have shown that low social and economic status and deprivation are significantly associated with an increased risk of oral cancer [9, 10]. …”

Section: Introductionmentioning

confidence: 99%

Low Survival Rates of Oral and Oropharyngeal Squamous Cell Carcinoma

Campion

Ribeiro

Luiz

et al. 2017

International Journal of Dentistry

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Aim To assess the epidemiological and clinical factors that influence the prognosis of oral and oropharyngeal squamous cell carcinoma (SCC). Methods One hundred and twenty-one cases of oral and oropharyngeal SCC were selected. The survival curves for each variable were estimated using the Kaplan-Meier method. The Cox regression model was applied to assess the effect of the variables on survival. Results Cancers at an advanced stage were observed in 103 patients (85.1%). Cancers on the tongue were more frequent (23.1%). The survival analysis was 59.9% in one year, 40.7% in two years, and 27.8% in 5 years. There was a significant low survival rate linked to alcohol intake (p = 0.038), advanced cancer staging (p = 0.003), and procedures without surgery (p < 0.001). When these variables were included in the Cox regression model only surgery procedures (p = 0.005) demonstrated a significant effect on survival. Conclusion The findings suggest that patients who underwent surgery had a greater survival rate compared with those that did not. The low survival rates and the high percentage of patients diagnosed at advanced stages demonstrate that oral and oropharyngeal cancer patients should receive more attention.

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“…Among the studies that involve questions related to associations between different geographical variables and spatial structure (33.3%), those which stand out are the methodological procedures with the LISA function, or local autocorrelation function (Galli;Neto, 2008;Paredes et al, 2010;Ferreira et al, 2012). Not many studies that involve more complex spatial questions about interaction and change were found; in these cases, the spatial prediction techniques stand out, such as Kriging (Camargo et al, 2008;Cruz, 2011).…”

Section: Resultsmentioning

confidence: 99%

Geografia e saúde coletiva no Brasil

Guimarães¹

2016

Saude soc.

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Resumo Este artigo faz uma reflexão a respeito da importância da geografia para a pesquisa em saúde coletiva no Brasil. Por meio de uma revisão bibliográfica narrativa, o autor descreve os principais temas abordados, agrupando os artigos selecionados de três das principais revistas brasileiras da área - Revista de Saúde Pública, Cadernos de Saúde Pública e Saúde e Sociedade - por escolas do pensamento geográfico. Discute também os avanços alcançados, assim como os desafios teóricos e metodológicos da saúde coletiva com base nos conhecimentos geográficos. Observou-se a importância do geoprocessamento em saúde para estudos de distribuição espacial, principalmente de doenças infectocontagiosas e parasitárias. Da mesma forma, foi possível identificar o crescimento da produção científica em estudos com base no pensamento crítico, com destaque para as publicações recentes na revista Saúde e Sociedade. A comparação dos trabalhos publicados também proporcionou a identificação de desafios metodológicos a serem enfrentados para o estudo da saúde coletiva com embasamento ainda maior de conhecimentos geográficos, como o uso de modelos preditivos e análise de superfícies de tendências, assim como o desenvolvimento de novas ferramentas cartográficas para a compreensão da realidade social em transformação e movimento.

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Desigualdade social no adoecimento e morte por câncer de boca e orofaríngeo no município de São Paulo, Brasil: 1997 a 2008

Cited by 11 publications

References 24 publications

Role of Inflammatory Markers in Prognosis of Oral Squamous Cell Carcinoma

Role of Inflammatory Markers in Prognosis of Oral Squamous Cell Carcinoma

Low Survival Rates of Oral and Oropharyngeal Squamous Cell Carcinoma

Geografia e saúde coletiva no Brasil

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