Dental caries status in human immunodeficiency virus-positive and acquired immunodeficiency syndrome patients

Malhotra, Amit; Ahlawat, Jyoti; Hegde, Mithra N; Mahajan, Ananya

doi:10.4103/0976-6944.194235

Cited by 4 publications

(4 citation statements)

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“…Many studies have attempted to relate certain aspects of salivary output and composition to caries susceptibility. 6 We conducted a survey to the patients visiting the Sememi Public Health Centre to find out if they have high Decayed, Missing, and Filled Teeth (DMFT) scores. Using the data we gathered, we identified our key population to determine and understand the factors influencing dental caries in HIV/AIDS patients.…”

Section: Introductionmentioning

confidence: 99%

Factors Influencing Dental Caries in HIV/AIDS Patients

Palupi¹,

Sosiawan²,

Wening³

et al. 2019

Acta Med Philipp

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Background. Human immunodeficiency viruses (HIV) / Acquired immunodeficiency syndrome (AIDS) is one of the most significant public health challenges in Surabaya, Indonesia where the greatest number of people living with HIV/AIDS (PLWHA) among key populations is in areas served by Sememi Public Health Center. HIV-infected persons have a greater risk for developing dental caries, such as salivary gland enlargement, and decreased salivary glands function. Given the fact that PLWHA are at high risk of dental caries, utilization of dental health service among PLWHA are still low. Objective. This study aims to know the factors influencing dental caries in HIV/AIDS patients.Methods. This is a descriptive, cross-sectional study conducted on 16 HIV-seropositive individuals. They were asked to complete a WHO questionnaire concerning basic oral health and quality of life. Dental caries was assessed using the Decayed, Missing, and Filled Teeth (DMFT) index. Whole stimulated saliva samples were also collected.Results. Nine out of 16 respondents had low salivary flow rate (56.3%). One patient had low DMF-T score (6.3%) and eight had high DMFT score (50%). Among seven respondents who had normal salivary flow rate (43.8%), two of whom had low DMFT score (12.5%) and five of whom had high DMFT score (31.3%).Conclusion. People living with HIV/AIDS have high DMFT and low salivary flow rate.

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Section: Introductionmentioning

confidence: 99%

Factors Influencing Dental Caries in HIV/AIDS Patients

Palupi¹,

Sosiawan²,

Wening³

et al. 2019

Acta Med Philipp

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“…HIV, ART combined with poor oral hygiene, knowledge and maintenance are mainly responsible for dental caries. [ 13 ] A higher mean DMFT score of HIV-positive individuals indicates their poor oral health status and warrants the need of special attention toward it. [ 11 ] Surprisingly, the North East region of India has no mention in the entire search.…”

Section: Discussionmentioning

confidence: 99%

Dental caries prevalence among HIV adult population in India: A systematic review

Acharya¹,

Muralidharan

Mallaiah

et al. 2020

J Oral Maxillofac Pathol

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“…This is of particular concern because many developing countries have a high burden of disease, which includes HIV. Moreover, it has been reported that people living with HIV/AIDS are at a higher risk of developing dental caries compared to the general population ( 8 , 9 ). For example, in Uganda, 1.3 million people are infected with HIV ( 10 ), and the prevalence of dental caries in this patient population was found to be 83.7% with a mean DMFT of 5.9 ( 11 ).…”

Section: Introductionmentioning

confidence: 99%

Microbial characteristics of dental caries in HIV positive individuals

Kalanzi

Mayanja‐Kizza

Nakanjako

et al. 2022

Front. Oral. Health

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BackgroundDental caries is a multifactorial disease that affects many people. Even though microorganisms play a crucial role in causing dental caries, diagnosis is routinely macroscopic. In order to improve early detection especially in HIV patients who are disproportionately affected, there is need to reconcile the macroscopic and microscopic characteristics of dental caries. Therefore, the aim of this study was to characterize the oral microbiota profile along the decayed, missing, filled teeth (DMFT) index using amplicon sequencing data.MethodsAmplicon sequencing of the V6-V8 region of the 16S rRNA gene was done on DNA recovered from whole unstimulated saliva of 59 HIV positive and 29 HIV negative individuals. The microbial structure, composition and co-occurrence networks were characterized using QIIME-2, Phyloseq, Microbiome-1.9.2 and Metacoder in R.ResultsWe characterized the oral microbiota into 2,093 operational taxonomic units (OTUs), 21 phyla and 239 genera from 2.6 million high quality sequence reads. While oral microbiota did not cluster participants into distinct groups that track with the DMFT index, we observed the following: (a) The proportion of accessory microbiota was highest in the high DMFT category while the core size (∼50% of richness) remained relatively stable across all categories. (b) The abundance of core genera such as Stomatobaculum, Peptostreptococcus and Campylobacter was high at onset of dental caries, (c) A general difference in oral microbial biomass. (d) The onset of dental caries (low DMFT) was associated with significantly lower oral microbial entropy.ConclusionsAlthough oral microbial shifts along the DMFT index were not distinct, we demonstrated the potential utility of microbiota dynamics to characterize oral disease. Therefore, we propose a microbial framework using the DMFT index to better understand dental caries among HIV positive people in resource limited settings.

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Dental caries status in human immunodeficiency virus-positive and acquired immunodeficiency syndrome patients

Cited by 4 publications

References 0 publications

Factors Influencing Dental Caries in HIV/AIDS Patients

Factors Influencing Dental Caries in HIV/AIDS Patients

Dental caries prevalence among HIV adult population in India: A systematic review

Microbial characteristics of dental caries in HIV positive individuals

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