Correlation Between Gingivitis and Orogranulocytic Migratory Rate

Abstract

The gingival index (GI) and the Orogranulocytic Migratory Rate (OMR) were determined for 86 subjects. The statistical analyses revealed a highly significant correlation between the two parameters. An analysis of regression demonstrated that the correlation of GI and OMR changed with low to high values of GI, probably because GI is not a true parametric index.

Novel rinse assay for the quantification of oral neutrophils and the monitoring of chronic periodontal disease

“…Earlier studies, which utilized time‐consuming serial rinses and counting techniques, found similar correlations (12,18). It has been previously shown that the rate at which oral neutrophils migrate into the oral cavity increases in the presence of inflammation (10) and that oral neutrophil counts positively correlate with both increasing pocket depth and the gingival index (11,12). Interestingly, Raeste & Aura (13) found that the leukocyte count in the first rinse of the OMR series also reflects the severity of periodontal disease.…”

“…The data obtained from this study demonstrates that it is possible to collect and quantify oral neutrophils using a single, rapid, noninvasive oral rinse assay. Compared with previous investigations, this rinse protocol is a practical, rapid and reproducible means of collecting and quantifying oral neutrophils from a clinical setting (9)(10)(11)(12)(13)18). We tested the reproducibility of this rinse protocol by performing duplicate rinses on subjects and controls on separate days before treatment.…”

“…The OMR also correlates with increased pocket depth and the gingival index. It is not sensitive to the presence of plaque, debris, or calculus (11,12). The idea of using neutrophil quantification to assess periodontal disease status and the effectiveness of therapy was first proposed by Raeste et al ., in 1978 (13).…”

Analysis of saliva for periodontal diagnosis

“…The OMR was found to be correlated with gingival index (Klinkhammer & Zimmerman 1969). In an experimental gingivitis model, the number of granulocytes in saliva increased before the appearance of clinical gingivitis (Friedman & Klinkhammer 1971, Skougaard et al 1969.…”

Leucocyte Count: A Window to Periodontal Disease? A Pilot Study

“…The results of the present study showed increase in the PMN leucocytes in GCF of cases or chronic generalized periodontitis patients compared to healthy controls. This could be attributed to increase surface area of ulcerated epithelium and hence increase in the migration of PMN leucocytes though the ulcerated epithelium in the cases [10]. Using neutrophil counts in the GCF to evaluate the periodontal disease activity has been used in earlier studies and has shown a positive correlation with the probing pocketdepth.…”