Chitosan/gelatin-tannic acid decorated porous tape suture with multifunctionality for tendon healing

Zhang, Qian; Qiao, Yansha; Li, Chaojing; Jing, Lin; Han, Hui; Li, Xiaoli; Wang, Fujun

doi:10.1016/j.carbpol.2021.118246

Cited by 24 publications

(20 citation statements)

References 53 publications

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“…In Figure 2 b, compared with the CS film, the hydroxyl peak of the COTA film at 3362 cm −1 showed an enhancement effect, signifying that OTA was successfully introduced into the structure of the CS. The peaks near 1630 cm −1 shifted to 1642 and 1645 cm −1 , which was related to the C=N bonds generated by the Schiff base reaction between the active o-quinone structure in the OTA and the CS amino group [ 34 ].…”

Section: Resultsmentioning

confidence: 99%

Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking

Qin

Huang²,

Xiao³

et al. 2022

IJMS

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Chitosan-based composite films with good biodegradability, biocompatibility, and sustainability are extensively employed in the field of food packaging. In this study, novel chitosan/tannic acid (CTA) and chitosan/oxidized tannic acid (COTA) composite films with excellent mechanical and antibacterial properties were prepared using a tape casting method. The results showed that, when 20% tannic acid (TA) was added, the tensile strength of the CTA composite film was 80.7 MPa, which was 89.4% higher than that of the pure chitosan (CS) film. TA was oxidized to oxidized tannic acid (OTA) with laccase, and the phenolic hydroxyl groups were oxidized to an o-quinone structure. With the addition of OTA, a Schiff base reaction between the OTA and CS occurred, and a dual network structure consisting of a chemical bond and hydrogen bond was constructed, which further improved the mechanical properties. The tensile strength of 3% COTA composite film was increased by 97.2% compared to that of pure CS film. Furthermore, these CTA films with significant antibacterial effects against Escherichia coli (E. coli) are likely to find uses in food packaging applications.

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Section: Resultsmentioning

confidence: 99%

Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking

Qin

Huang²,

Xiao³

et al. 2022

IJMS

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“…Without UV and initiator, herein, TA extracted from tea was utilized for directly crosslinking with 5% (w/v) GelMA in PBS solution. It has been reported that TA could crosslink with hydrogels through hydrogen binding effects reported [ 35 , 36 ] in different fields including wound repair [ 37 , 38 ], clinical sutures [ 44 ] and refs [ 35 , 45 ]. As presented in Fig.…”

Section: Resultsmentioning

confidence: 99%

Tannic acid-loaded hydrogel coating endues polypropylene mesh with hemostatic and anti-inflammatory capacity for facilitating pelvic floor repair

Zhou²,

You

et al. 2022

Regenerative Biomaterials

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The application of polypropylene mesh (PPM) in pelvic organ prolapse (POP) treatment was severely limited by the complications associated with PPM, such as mesh exposure, chronic inflammatory reactions, and postoperative hematoma. This study applied a method of fabricating a hydrogel-mesh complex (PPM+TA@GelMA) to cross-link tannic acid (TA) directly with Methacrylate Gelatin (GelMA) hydrogel and thus to form a coating for polypropylene mesh. This one-step coating modification improved the hydrophilicity and cyto-compatibility of PPM. The hemostatic effect of PPM+TA@GelMA was confirmed through tail amputation test. Through the defect tissue repair experiments in vivo, it was proved that PPM+TA@GelMA had effects of anti-inflammation and promoting tissue repair, and regulated the M2 subtype macrophages polarization for tissue repair. The TA-loaded hydrogel coating endued PPM with multiple functions. It is believed that the novel hydrogel-mesh complex and its fabrication method will have great significance in basic research and clinical application.

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“…In vivo experiments (mice models) indicated that the suture could not only reduce inflammatory index but also promote collagen and blood vessel generation. Although the collagen formation was mainly caused by the gelatine-based hydrogel, the anti-inflammatory behaviour was related to biological activities of tannic acid [ 64 ]. Also, gelatine-based bioinks, containing muscle and tendon cells, were employed to fabricate complex 3D printed muscle-tendon junction scaffolds [ 65 ] where the gelatine-based bioinks enabled the expression of the muscle- and tendon-specific proteins for the muscle and tendon sides, receptively.…”

Section: Biopolymersmentioning

confidence: 99%

Natural, synthetic and commercially-available biopolymers used to regenerate tendons and ligaments

Heidari

Ruan

Vahabli

et al. 2023

Bioactive Materials

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Chitosan/gelatin-tannic acid decorated porous tape suture with multifunctionality for tendon healing

Cited by 24 publications

References 53 publications

Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking

Preparation and Characterization of High Mechanical Strength Chitosan/Oxidized Tannic Acid Composite Film with Schiff Base and Hydrogen Bond Crosslinking

Tannic acid-loaded hydrogel coating endues polypropylene mesh with hemostatic and anti-inflammatory capacity for facilitating pelvic floor repair

Natural, synthetic and commercially-available biopolymers used to regenerate tendons and ligaments

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