Characterization of the Running-in Period in Total Hip Resurfacing Arthroplasty: An in Vivo and in Vitro Metal Ion Analysis

Heisel, Christian; Streich, N.; Krachler, Michael; Jakubowitz, Eike; Kretzer, Jan Philippe

doi:10.2106/jbjs.h.00437

Cited by 89 publications

(74 citation statements)

References 27 publications

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“…3). Similar progressions are reported for wear studies on metal-onmetal joint bearings in total hip replacement [10]. During the initial run-in phase of those implants, the surface geometries of both counterparts adapt to each other.…”

Section: Discussionsupporting

confidence: 70%

“…The titanium concentration of the serum was analysed using HR-ICP-MS (Element2, Thermo Fisher Scientific, Bremen, Germany) at intervals of 0, 1×10 6 , 2×10 6 , 4.5×10 6 , 7×10 6 and 10×10 6 cycles. In order to detect not only ions but also particles in the serum, the samples were first digested with high purity nitric acid (HNO 3 ) and hydrogen peroxide (H 2 O 2 ) following a standardised, well-established procedure [10]. The titanium mass was calculated based on the test medium's volume and the measured titanium concentration.…”

Section: Methodsmentioning

confidence: 99%

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Metal release and corrosion effects of modular neck total hip arthroplasty

Kretzer

Jakubowitz

Krachler

et al. 2009

International Orthopaedics (SICOT)

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Modular neck implants are an attractive treatment tool in total hip replacement. Concerns remain about the mechanical stability and metal ion release caused by the modular connection. Five different implant designs were investigated in an experimental set-up. In vivo conditions were simulated and the long-term titanium release was measured. Finally, the modular connections were inspected for corrosion processes and signs of fretting. No mechanical failure or excessive corrosion could be identified for the implants tested. The titanium releases measured were extremely low compared to in vivo and in vitro studies and were not in a critical range.Résumé Dans les prothèses totales de hanche l'utilisation d'implants avec col modulaire est d'une utilisation fré-quente et pratique. Néanmoins, cette utilisation laisse persister des doutes sur la stabilité mécanique et sur le relargage des ions métalliques. 5 différents implants ont été étudiés en reproduisant les conditions in vivo, en mesurant le relargage de titane et en évaluant la corrosion et les lésions du col. Ce travail n'a pas permis de mettre en évidence d'échec secondaire à une corrosion excessive, et les taux de titane sont restés extrêmement bas dans les limites de l'acceptable.

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Section: Discussionsupporting

confidence: 70%

Section: Methodsmentioning

confidence: 99%

Metal release and corrosion effects of modular neck total hip arthroplasty

Kretzer

Jakubowitz

Krachler

et al. 2009

International Orthopaedics (SICOT)

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“…We included hips of several current-generation designs, all with monoblock cups and a large internal diameter ([ 38 mm) suitable for either resurfacing or large-diameter MOM THA. For the purposes of wear analysis, we required that all hips were implanted for a minimum of 12 months to minimize the confounding effect of the bedding-in process [18]. All patients revised with a diagnosis of infection were excluded to ensure all pseudotumors were sterile inflammatory masses.…”

Section: Methodsmentioning

confidence: 99%

Pseudotumors Are Common in Well-positioned Low-wearing Metal-on-Metal Hips

Matthies

Skinner

Osmani

et al. 2012

Clinical Orthopaedics &Amp; Related Research

138

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Background Pseudotumors are sterile inflammatory lesions found in the soft tissues surrounding metal-on-metal (MOM) and metal-on-polyethylene hip arthroplasties. In patients with MOM hip arthroplasties, pseudotumors are thought to represent an adverse reaction to metal wear debris. However, the pathogenesis of these lesions remains unclear. Currently, there is inconsistent evidence regarding the influence of adverse cup position and increased wear in the formation of pseudotumors. Questions/purposes We therefore determined whether pseudotumor formation was associated with (1) adverse cup position, (2) raised metal ion levels, and (3) increased wear rates of the retrieved components. Methods We retrospectively reviewed all 352 patients for whom we had retrieved specimens from revisions of a current-generation MOM hip prosthesis between February 2008 and September 2010; of these, 105 met our inclusion criteria. We used multivariate logistic regression analysis to compare acetabular orientation, metal ion levels before revision, and component wear rates between patients with (n = 72) and without (n = 33) pseudotumors, according to findings on metal artifact reduction sequence MRI. Results The proportion of patients demonstrating evidence of a pseudotumor in well-positioned hips was similar to those with adverse cup positions (67% and 66%, respectively). Patients revised with pseudotumors had similar whole-blood metal ion levels and component wear rates to those who were not revised. Conclusions Pseudotumors were not associated with increased wear or metal ion levels, suggesting patient susceptibility is likely to be more important.

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“…This is supported by the experimental results presented by Wimmer (Wimmer et al, 2003), Liao (Liao et al, 2013;Liao et al, 2011), Yan (Yan et al, 2009), Hesketh (Hesketh et al, 2013) and Heisel et al (Heisel et al, 2008) who have all demonstrated that such films can reduce wear and corrosion, along with a stoichiometric release of metallic ions into the bulk environment. The formation of tribo-films within the articulation is -oxidation and improving lubrication.…”

Section: Figure 15mentioning

confidence: 53%

Characterisation of the surface topography, tomography and chemistry of fretting corrosion product found on retrieved polished femoral stems

Bryant

Ward

Farrar³

et al. 2014

Journal of the Mechanical Behavior of Biomedical Materials

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eprints@whiterose.ac.uk https://eprints.whiterose.ac.uk/ Reuse Unless indicated otherwise, fulltext items are protected by copyright with all rights reserved. The copyright exception in section 29 of the Copyright, Designs and Patents Act 1988 allows the making of a single copy solely for the purpose of non-commercial research or private study within the limits of fair dealing. The publisher or other rights-holder may allow further reproduction and re-use of this version -refer to the White Rose Research Online record for this item. Where records identify the publisher as the copyright holder, users can verify any specific terms of use on the publisher's website. TakedownIf you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing eprints@whiterose.ac.uk including the URL of the record and the reason for the withdrawal request. CHARACTERISATION OF THE SURFACE TOPOGRAPHY, TOMOGRAPHY HIGHLIGHTS: The tomography of retrieved femoral stems was characterised. Directionality and plastic deformation of the metallic surfaces was seen. Thick deposited layers were seen to occur within the stem-cement interfaces. Films of Cr2O3 bound with organic material play an important role in the degradation.

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Characterization of the Running-in Period in Total Hip Resurfacing Arthroplasty: An in Vivo and in Vitro Metal Ion Analysis

Cited by 89 publications

References 27 publications

Metal release and corrosion effects of modular neck total hip arthroplasty

Metal release and corrosion effects of modular neck total hip arthroplasty

Pseudotumors Are Common in Well-positioned Low-wearing Metal-on-Metal Hips

Characterisation of the surface topography, tomography and chemistry of fretting corrosion product found on retrieved polished femoral stems

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