Assessment of immediate pain relief with laser treatment in recurrent aphthous stomatitis

Prasad, Ramesh; Pai, Anuradha

doi:10.1016/j.oooo.2013.02.011

Cited by 43 publications

(72 citation statements)

References 18 publications

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“…Immediate relief of pain and a significant improvement in healing time with a single session of Carbon dioxide (CO 2 ) laser treatment in patients with minor RAS has been reported in randomised controlled trials [90,91]. More recently, Botulinum toxin has been reported as effective [92].…”

Section: Other Treatments Of Rasmentioning

confidence: 99%

Recurrent Aphthous Stomatitis: Towards Evidence-Based Treatment?

Challacombe

Alsahaf

Tappuni

2015

Curr Oral Health Rep

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Recurrent aphthous stomatitis is one of the most common oral mucosal diseases seen by dental professionals, and yet its aetiology remains unclear, and its management based on less than robust evidence. The literature remains confused because of the lack of clarity in diagnosis and the lack of a standardised ulcer severity scoring system and agreed outcome measures. However, recent literature is encouraging in meeting these aims. There is agreement that recurrent aphthous stomatitis (RAS) is a localized mucosal disease not secondary to systemic disease and therefore distinguishable from over 40 other types of oral ulcers. Disease severity scores have been introduced and outcome measures have become more standardised. RAS appears to be an autoimmune disease directed at epitopes of heat shock proteins whilst most recent work on aetiology has focused on cytokines and genetics. Pro-inflammatory cytokines including TNF-a and IL-6 and IL-17 are raised in RAS and TNF inhibitors can inhibit episodes of ulceration. Many local antiinflammatory agents will help ulcers heal, and local steroids remain the treatment of choice. Some systemic drugs have evidence-based data indicating efficacy at preventing new ulcers including colchicine, prednisolone, thalidomide, pentoxyfilline and dapsone. The field would benefit from further trials combining local and systemic therapy using defined outcome measures.

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Section: Other Treatments Of Rasmentioning

confidence: 99%

Recurrent Aphthous Stomatitis: Towards Evidence-Based Treatment?

Challacombe

Alsahaf

Tappuni

2015

Curr Oral Health Rep

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“…All studies compared the effectiveness of one kind of laser with a negative treatment (an inactive laser therapy or conventional medical therapy). Among these reports, four studies [36–38, 40] made a comparison between the CO 2 laser treatment and an inactive laser treatment (placebo group). In those studies applied with CO 2 laser, before irradiation, a layer of transparent, high-water, and nonanesthetic gel was placed on the lesion in patients of the laser and placebo groups.…”

Section: Resultsmentioning

confidence: 99%

Effectiveness of Laser Therapy in the Management of Recurrent Aphthous Stomatitis: A Systematic Review

Han

Fang

et al. 2016

Scientifica

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Objectives. Laser therapy is a promising new treatment for patients with recurrent aphthous stomatitis (RAS). However, the clinical effect and security issue of laser therapy remain controversial. This systematic review was conducted to evaluate the clinical effectiveness and security of laser treatment in RAS patients. Methods. Five electronic databases were searched (MEDLINE (PubMed), EMBASE, ScienceDirect, the Cochrane Library, and Web of Science) to identify all studies that were about randomized controlled clinical trials, involving the effect of laser therapy in RAS patients. Conclusion. Twenty-three studies were retained for full-text analysis after screening the titles and abstracts of potential articles, but only 10 studies satisfied the inclusion criteria after the full texts were reviewed. The included studies reported a comparison of the effectiveness between the laser treatment and placebo laser therapy (or conventional drug therapy) when managing the RAS patients. It can be concluded that laser therapy has the superiority in relieving ulcer pain and shortening healing time when compared with placebo group or medical treatment group. Although laser therapy is a promising effective treatment for RAS, high-quality clinical studies with large sample size must be further performed to confirm the effectiveness of this therapy.

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“…Outra modalidade de tratamento, apresentada por três artigos, foi o uso de laser de baixa potência (Quadro 3), considerada uma alternativa de tratamento por oferecer melhor resposta inflamatória com redução de edema e de dor, além da bioestimulação celular para regeneração tecidual 39 . Prasad e Pai 19 analisaram o efeito da aplicação de uma única sessão de laser de CO 2 no alívio da dor provocada pela úlcera, e concluíram que esse tratamento foi eficaz, além de diminuir o tempo de cicatrização da úlcera. Resultados semelhantes foram encontrados no estudo conduzido por Aggarwal et al 37 , com melhor tempo de cicatrização completa das úlceras e com alívio da dor imediata.…”

Section: Discussionunclassified

“…Dessa forma, a EAR representa um problema que requer atenção, devido à sua alta prevalência e associação com dor e influência na qualidade de vida dos indivíduos afetados 13 . Como tratamento, são indicados variados agentes terapêuticos, dentre eles, medicamentos sistê-micos e agentes tópicos têm sido utilizados na redução dos sintomas e na busca de uma acelerada regeneração dessa lesão 14,15 , tais como a utilização de produtos naturais 16 , antibióticos 5 , anti-inflamatórios 17 , vitaminas 18 ou laser 19 . Desse modo, tendo em vista a alta prevalência da estomatite aftosa recorrente, suas implicações na qualidade de vida do paciente e suas inúmeras alternativas de tratamento, o presente trabalho busca realizar uma revisão integrativa de publicações científicas sobre os tratamentos da estomatite aftosa recorrente, no intuito de subsidiar a prática clínica no manejo dessa condição.…”

Section: Objetivo: Realizar Uma Revisão Integrativa De Publicações CIunclassified

Tratamento da estomatite aftosa recorrente: uma revisão integrativa da literatura

Vieira

Carmo

Vieira

et al. 2016

Rev. da Fac. de Odontologia, UPF

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IntroduçãoA estomatite aftosa recorrente (EAR) é uma condição comum caracterizada por úlceras múltiplas, pequenas, ovoides, com margem circunscrita, halo eritematoso e fundo amarelo ou cinza, com aparecimento típico primeiramente na infância ou adolescência 1 . A manifestação dessa alteração dá-se em surtos e com um curso crônico, com tempo limitado da lesão, na maior parte dos casos 2,3 . Do ponto de vista epidemiológico, a EAR é uma das mais comuns desordens orais, conhecida por afetar cerca de 20% da população em algum momento da vida 4 . Apesar de sua alta prevalência na população, sua etiopatogenia perdura como um enigma, pois, mesmo com muitas investigações, os estudos têm falhado em encontrar a sua exata etiologia

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Assessment of immediate pain relief with laser treatment in recurrent aphthous stomatitis

Cited by 43 publications

References 18 publications

Recurrent Aphthous Stomatitis: Towards Evidence-Based Treatment?

Recurrent Aphthous Stomatitis: Towards Evidence-Based Treatment?

Effectiveness of Laser Therapy in the Management of Recurrent Aphthous Stomatitis: A Systematic Review

Tratamento da estomatite aftosa recorrente: uma revisão integrativa da literatura

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