Antibacterial effect of silver nanoparticles on Staphylococcus aureus

Mirzajani, Fateme; Ghassempour, Alireza; Aliahmadi, Atousa; Esmaeili, Mohammad Ali

doi:10.1016/j.resmic.2011.04.009

Cited by 277 publications

(165 citation statements)

References 28 publications

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“…As a consequence ribosomes may be denatured with inhibition of protein synthesis, as well as translation and transcription can be blocked by the binding with the genetic material of the bacterial cell [33,59,60]. Protein synthesis has been shown to be altered by treatment with AgNPs and proteomic data have shown an accumulation of immature precursors of membrane proteins resulting in destabilization of the composition of the outer membrane [61]. In Figure 1 we summarize the possible toxicity mechanisms of AgNPs.…”

Section: Salmonella Typhimentioning

confidence: 99%

Silver Nanoparticles as Potential Antibacterial Agents

et al. 2015

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Multi-drug resistance is a growing problem in the treatment of infectious diseases and the widespread use of broad-spectrum antibiotics has produced antibiotic resistance for many human bacterial pathogens. Advances in nanotechnology have opened new horizons in nanomedicine, allowing the synthesis of nanoparticles that can be assembled into complex architectures. Novel studies and technologies are devoted to understanding the mechanisms of disease for the design of new drugs, but unfortunately infectious diseases continue to be a major health burden worldwide. Since ancient times, silver was known for its anti-bacterial effects and for centuries it has been used for prevention and control of disparate infections. Currently nanotechnology and nanomaterials are fully integrated in common applications and objects that we use every day. In addition, the silver nanoparticles are attracting much interest because of their potent antibacterial activity. Many studies have also shown an important activity of silver nanoparticles against bacterial biofilms. This review aims to OPEN ACCESSMolecules 2015, 20 8857 summarize the emerging efforts to address current challenges and solutions in the treatment of infectious diseases, particularly the use of nanosilver antimicrobials.

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Section: Salmonella Typhimentioning

confidence: 99%

Silver Nanoparticles as Potential Antibacterial Agents

et al. 2015

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“…3). The bactericidal efficacy of the NPs is influenced by concentration, size and shape of NPs and the studied microrganisims [83,84] . Small sized NPs seems to have a high tendency to penetrate deeper into the bacterial cell wall, and interact with the membrane leading to cell membrane damage.…”

Section: Antimicrobial Activity Of Npsmentioning

confidence: 99%

Advances in Biogenic Nanoparticles and the Mechanisms of antimicrobial Effects

Qidwai¹,

ey²,

Sureshkumar³

et al. 2018

pharmaceutical-sciences

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Qidwai, et al.: Biogenic Advances in NanoparticlesInnovations in the nanotechnological arena have paved a path leading to nano-revolution, which has most recently unfurled the role of plants in the biogenic synthesis of nanoparticles. Though synthesis of nanoparticles can be accomplished through physical and chemical techniques, biological course of synthesis has proficiently proved competent over other techniques. The problem of evolving multidrug resistant bacteria, due to irrational use of antibiotics, makes the biogenically synthesized nanoparticles attractive, due to their promising efficacy with negligible side effects. Consequently, the nanoparticles becoming better substitutes for conventional treatment besides overcoming all the limitations. Nanoparticles have great stability and potent antibacterial activity. The uniqueness lies in their size (10 and 500 nm) and dimension offers these particles to dynamically communicate with biomolecules on the cell surfaces and within the cells, so proficiently to decode and designate various biochemical and physiochemical properties of the cells. The present review aims to recapitulate various emerging efforts in the biogenic synthesis of nanoparticles, most significantly their unique mechanisms of action with different approaches as well as the factors that may add up to their antimicrobial activity.

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“…silver nanoparticles). Badania wykazują, że działanie bakteriobójcze AgNPs występuje nawet przy bardzo niskich stężeniach, co może być spowodowane dużą reaktywnością związaną z małym rozmiarem cząstek i dużą powierzchnią oddziaływania z bakteriami (Cho, Park, Osaka i Park, 2005;Oleszkiewicz, Korzekwa i Bugia-Płoskońska, 2008;Petica, Gavriliu, Lungu, Buruntea i Panzaru, 2008;Mirzajani, Ghassempour, Aliahmadi i Esmaeili, 2011). Autorzy powyższych prac udowodnili, że wraz ze zmniejszaniem wielkości nanocząstek rośnie ich aktywność bakteriobójcza.…”

Section: Wstępunclassified