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Recently, green synthesis of silver nanoparticles has attracted much curiosity in the field of life science research. In the present study, we have reported a green method for synthesis of silver nanoparticles (AgNPs) using aqueous seed extract of Phoenix sylvestris L. The green synthesized nanoparticles were characterized by aids of dynamic light scattering, scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and Fourier transform-infrared.Further, the study demonstrate the comparative phytochemical analysis as well as antioxidant and antibacterial activity of the extract and Phoenix sylvestris seed generated nanoparticles against acne-causing pathogens, that is, by using a DPPH-scavenging assay and broth microdilution method as well as Kirby-Bauer Disk diffusion method (recommended by CLSI), respectively. Moreover, a concentration-dependent time-kill kinetic studies were also carried out to determine their antimicrobial activity. The seed extract was found a better antioxidant and AgNPs exhibited highly biocidal agent against both the test pathogens, when compared to aqueous extracts. The results obtained indicate that seed extract of P. sylvestris is suitable for synthesizing stable silver nanoparticles, which act as excellent antimicrobial agents with promising treatments for cosmetics embarrassment. ARTICLE HISTORY

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Qidwai, et al.: Biogenic Advances in NanoparticlesInnovations in the nanotechnological arena have paved a path leading to nano-revolution, which has most recently unfurled the role of plants in the biogenic synthesis of nanoparticles. Though synthesis of nanoparticles can be accomplished through physical and chemical techniques, biological course of synthesis has proficiently proved competent over other techniques. The problem of evolving multidrug resistant bacteria, due to irrational use of antibiotics, makes the biogenically synthesized nanoparticles attractive, due to their promising efficacy with negligible side effects. Consequently, the nanoparticles becoming better substitutes for conventional treatment besides overcoming all the limitations. Nanoparticles have great stability and potent antibacterial activity. The uniqueness lies in their size (10 and 500 nm) and dimension offers these particles to dynamically communicate with biomolecules on the cell surfaces and within the cells, so proficiently to decode and designate various biochemical and physiochemical properties of the cells. The present review aims to recapitulate various emerging efforts in the biogenic synthesis of nanoparticles, most significantly their unique mechanisms of action with different approaches as well as the factors that may add up to their antimicrobial activity.

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Objective: The aim of the present study is to deal with the population based field study regarding factors that might play essential role in occurrence or epidemiology of Acne vulgaris in north central India. Methods:This cross-sectional study was a population based field study. Populations were assessed for influence of various factors on acne prevalence. The study was carried out from April 2016 to October 2016 in north central India. For this survey, questionnaires were designed to cover all the required information regarding the incidence of acne that includes factors such as gender, age, skin type, complexion, season of the incidence, and dietary habit. Results: Acne vulgaris appears to be influenced by gender, age, seasonal variations, breakout area, complexion, skin types, and dietary habits. Further, the influence of dietary habit on acne, particularly the consumption of dairy products or high-carbon diet has also been evaluated. Apart from depicting the vulnerable range of age (p=0.003288), sensitivity on various skin types (P=0.00039) and complexion (P=0.001355) on the basis of gender; this field study on acne vulgaris, also reveals that the season has inordinate role in acne pervasiveness (P=0.115731). Conclusion:This study is helpful in categorizing the risk factors and manifesting the afflictions of acne in population thus, contributing health-care planning.

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