Amount and type of alcohol and periodontitis in the Copenhagen City Heart Study

Kongstad, Johanne; Hvidtfeldt, Ulla Arthur; Grønbæk, Morten; Jontell, Mats; Stoltze, Kaj; Holmstrup, Palle

doi:10.1111/j.1600-051x.2008.01325.x

Cited by 38 publications

(44 citation statements)

References 24 publications

(57 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the effect of alcohol on the oral microbiota was not examined in this study, it has been shown that anaerobes were significantly reduced when the frequencies for wine and coffee drinkers were compared with the frequencies for subjects in the control group [21,29]. Our findings also agreed with a study by Kongstad et al [30] who found that higher alcohol consumption, particularly intake of wine, was inversely associated with clinical periodontal attachment level in men, but not in women. However, alcohol consumption has been found to moderately increase the severity of periodontal disease but not alveolar bone loss [31].…”

Section: Discussionsupporting

confidence: 94%

Oral infection, regular alcohol drinking pattern, and myocardial infarction

Håheim¹,

Olsen²,

Rønningen³

2012

Medical Hypotheses

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 94%

Oral infection, regular alcohol drinking pattern, and myocardial infarction

Håheim¹,

Olsen²,

Rønningen³

2012

Medical Hypotheses

View full text Add to dashboard Cite

“…As determinant of periodontitis, we used a mean loss of attachment of at least 2.55 mm [27,37,38]. This may not be a precise assessment measure of the disease processes associated with periodontitis, because it only includes evidence of past tissue degeneration and not the current state of the disease.…”

Section: Discussionmentioning

confidence: 99%

Immunoglobulin G antibodies againstPorphyromonas gingivalisorAggregatibacter actinomycetemcomitansin cardiovascular disease and periodontitis

Damgaard

Reinholdt

Enevold

et al. 2017

Journal of Oral Microbiology

Self Cite

View full text Add to dashboard Cite

Objectives: The aim was to elucidate whether levels of circulating antibodies to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis correlate to loss of attachment, as a marker for periodontitis and cardiovascular disease (CVD). Design: Sera were collected from 576 participants of the Danish Health Examination Survey (DANHES). Immunoglobulin G antibodies against lipopolysaccharide (LPS) and protein antigens from the a, b and c serotypes of A. actinomycetemcomitans and P. gingivalis were quantified by titration in ELISA plates coated with a mixture of antigens prepared by disintegration of bacteria. Results: Levels of antibodies against P. gingivalis (OR = 1.48) and A. actinomycetemcomitans (1.31) associated with periodontitis, as determined by univariable logistic regression analysis. These antibody levels also associated with CVD (1.17 and 1.37), respectively, However, after adjusting for other risk factors, including age, smoking, gender, alcohol consumption, overweight, and level of education using multivariable logistic regression analysis, only increasing body mass index (BMI; 1.09), previous smoking (1.99), and increasing age (decades) (2.27) remained associated with CVD. Increased levels of antibodies against P. gingivalis (1.34) remained associated with periodontitis after adjusting for other risk factors. Conclusions: CVD and periodontitis were associated with levels of IgG antibodies to P. gingivalis or A. actinomycetemcomitans in univariable analyses, but only the association of P. gingivalis antibody levels with periodontitis reached statistical significance after adjustment for common confounders. Age, in particular, influenced this relationship.

show abstract

“…Similar findings were observed in other studies in rats [12][13] . A previous study 7 related alcohol consumption with periodontitis and obtained conflicting results, showing that higher alcohol consumption appears to have an inverse association with attachment loss in men, but not in women. The authors emphasized that further investigation is necessary to observe the association between alcohol and periodontitis, establishing prospective cohort studies with participants free of periodontitis at baseline.…”

Section: Discussionmentioning

confidence: 91%

“…However, more recent studies on humans have shown no relation between periodontal disease and alcohol consumption [6][7] . The use of rat models has been applied in the evaluation of periodontal pathogenesis 8 and regarding the influence of risk indicator/factors, such as estrogen deficiency [9][10] , alcohol consumption [11][12][13][14][15][16] , nicotine 17 and simultaneous nicotine and alcohol use 18 on disease progression.…”

Section: Introductionmentioning

confidence: 99%

Effects of alcohol intake in periodontitis progression in female rats: a histometric study

Souza¹,

Ricardo²,

Rocha³

2014

Braz. J. Oral Sci.

View full text Add to dashboard Cite

Aim: To evaluate histometrically the effect of low and high caloric value of ethanol on ligatureinduced bone loss in female rats. Methods: Sixty female rats were divided into five groups of 12 animals each: Normal Control (water), Test A (low ethanol), Control A (low iso), Test B (high ethanol) and Control B (high iso). Control Groups A and B received diets with the same amount of calories consumed by Test Groups A and B, respectively, with ethanol replaced by isocaloric amounts of carbohydrate. Four weeks prior to the end of the experimental period, half of the rats in each group were randomly assigned to receive a ligature on mandibular molar, whereas the other half of group was left unligated. At 8 weeks, the animals were sacrificed, and the specimens were processed to obtain decalcified sections. The area of periodontal ligament and/or bone loss in the furcation region of the first molars was histometrically measured in five sections per specimen (mm²). Results: Ethanol intake did not have effect on the alveolar bone loss in unligated teeth (p>0.05). However, in ligature-induced periodontitis, high value of calories associated with ethanol feeding enhanced the area of bone loss (p<0.05). Conclusions: The results of this study demonstrated that a low-ethanol diet did not affect the periodontium, while a high-ethanol diet may aggravate the progression of periodontitis, as demonstrated by the increased furcation region bone destruction in periodontal disease.

show abstract

Amount and type of alcohol and periodontitis in the Copenhagen City Heart Study

Abstract: The results indicate that higher alcohol consumption, particularly intake of wine, is inversely associated with CAL in men. Such an association is not found in women.

Cited by 38 publications

References 24 publications

Oral infection, regular alcohol drinking pattern, and myocardial infarction

Oral infection, regular alcohol drinking pattern, and myocardial infarction

Immunoglobulin G antibodies againstPorphyromonas gingivalisorAggregatibacter actinomycetemcomitansin cardiovascular disease and periodontitis

Effects of alcohol intake in periodontitis progression in female rats: a histometric study

Contact Info

Product

Resources

About