AIA-1200 Immunoassay System

Chan, Daniel W.; Thornton, Pamela L.

doi:10.1016/b978-0-12-167632-2.50014-9

Cited by 5 publications

(2 citation statements)

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“…For the determination of glucose and insulin, serum samples were used. Glucose was determined by means of the glucose oxidase method [10] and insulin by a two-site immunoenzymometric method [11]. Glycosylated hemoglobin was determined by high-performance liquid chromatography on a Biorad variant II analyzer.…”

Section: Methodsmentioning

confidence: 99%

Effect of Diabetes mellitus and Different Treatments on Plasma and Erythrocyte Phospholipid Fatty Acid Composition inType 2 Diabetics

Rodríguez

Christophe

2004

Ann Nutr Metab

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Aim: The aim of the present study was to determine how the fatty acid composition of plasma and erythrocyte phospholipids is influenced by the diabetic condition and by dietary or glibenclamide treatment in type 2 diabetes. Methods: The fatty acid composition of plasma and erythrocyte phospholipids is assessed in 3 nonobese groups of Cuban diabetics with comparable age and BMI: 13 newly diagnosed, 15 on diet alone and 15 on diet/glibenclamide. Thirteen healthy individuals were used as controls. Fasting serum glucose, insulin and glycosylated hemoglobin and dietary fat intake were assessed. Results: In plasma phospholipids, significant lower values were found for 14:0, 15:0 and 17:0 in newly diagnosed patients than in controls. In red blood cell phospholipids, 14:1, 20:0 and 24:1 of newly diagnosed patients were significantly lower than of controls, and 16:1ω7 and 18:4ω3 were significantly higher. The different treatments had an effect on 18:0, 18:1t, 20:0 and total trans fatty acids in erythrocyte, but not in plasma phospholipids. Conclusions: Changes in plasma phospholipid fatty acids found in type 2 diabetics may be due to an ‘adapted’ dietary pattern, whereas those in erythrocyte phospholipids may be attributed to effects of the disease itself and may be susceptible to normalization by diet or glibenclamide.

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Section: Methodsmentioning

confidence: 99%

Effect of Diabetes mellitus and Different Treatments on Plasma and Erythrocyte Phospholipid Fatty Acid Composition inType 2 Diabetics

Rodríguez

Christophe

2004

Ann Nutr Metab

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“…The instrument is a floor-standing model (4,5,6). Reagents and samples react in disposable plastic cups, the ΑΙΑ-Packs, which contain antibody-coated magnetic beads and lyophilized alkaline phosphatase !…”

Section: Aia-1200mentioning

confidence: 99%

Comparison of the Automated Random Access Immunoassay Analysers, ACS-180 (Ciba Corning) and AIA-1200 (Tosoh)

Costongs

Janson²

1993

Clinical Chemistry and Laboratory Medicine

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Summary:Two random access immunoassay analysers, the ACS-180 (Ciba Corning) and the AIA-1200 (Tosoh Corp.) were compared with respect to performance and user-friendliness. Precision studies revealed an almost equal intra-assay variation coefficient, but day-to-day reproducibility was better on the AIA-1200. Recovery of dilution series of tumour markers was too high with the ACS-180. Both systems were free from carry-over effects, on account of the extra wash step in the ACS-180 (for thyrotropin, carcinoembryonic antigen and human chorionic gonadotropin) and the separate pipetting tip in the AIA-1200. Reagent stability is better in the AIA-1200 than in the ACS-180. The AIA-1200 is more user-friendly and produces a higher throughput than the ACS-180 in daily routine operation (92 results/hour vs. 78 results/hour).

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Automation of Immunoassays

Chan

1996

Immunoassay

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AIA-1200 Immunoassay System

Cited by 5 publications

References 0 publications

Effect of Diabetes mellitus and Different Treatments on Plasma and Erythrocyte Phospholipid Fatty Acid Composition inType 2 Diabetics

Effect of Diabetes mellitus and Different Treatments on Plasma and Erythrocyte Phospholipid Fatty Acid Composition inType 2 Diabetics

Comparison of the Automated Random Access Immunoassay Analysers, ACS-180 (Ciba Corning) and AIA-1200 (Tosoh)

Automation of Immunoassays

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