Correlation of Dry Eye Workshop Dry Eye Severity Grading System With Tear Meniscus Measurement by Optical Coherence Tomography and Tear Osmolarity

Abstract

Both tear osmolarity and tear meniscus OCT measurements comply with the DEWS grading system, and they can be used in the diagnosis and follow-up of dry eye patients in addition to conventional tests.

Diagnostic value of three simple and rapid dry eye tests: Lid parallel conjunctival folds, tear meniscus height and tear ferning

“…Garsia-Resua et al found that there is a good correlation between osmolarity and subjective grading of TMH as well as measuring of TMH using open-source software (NIH ImageJ) [19]. Both tear osmolarity and tear meniscus OCT measurements comply with the DEWS grading system as previously reported by Tukenmez-Dikmen et al [20] Mean values of TMH and LIPCOF between different grades of DE didn't show statistically significant difference, so according to our result they are not convenient for grading DE. In our study mean value of TMH in group without DE was 0.17 mm.…”

Evaluation of lacrimal production, osmolarity, crystallization, proteomic profile, and biochemistry of capuchin monkeys’ tear film

“…Patients with dry eye have decreased SMT values, and therefore, measuring the meniscus length and correlating it with osmolarity in these patients can yield parameters of great importance . In healthy CM, there was no significant correlation between SMT and osmolarity, in contrast to the results for humans, which might have been influenced by the significantly higher values of the LE.…”

Effect of different lubricant eye gels on tear film thickness as measured with ultrahigh‐resolution optical coherence tomography

“…Points on the grading scale that did not occur in any group are not shown. Palakuru et al 2007Palakuru et al , 2008Ibrahim et al 2010;Koh et al 2010;Chen et al 2011;Park et al 2012;Qiu et al 2012;Altan-Yaycioglu et al 2013;Fukuda et al 2013;Bartuzel et al 2014;Canan et al 2014;Sizmaz et al 2014;Akiyama et al 2015;Tukenmez-Dikmen et al 2015). For measuring precorneal tear film, the resolution of commercially available OCT systems is not sufficient for quantitative measurement.…”