Epiretinal Membranes in Patients with Uveitis: Morphological and Functional Analysis with Spectral Domain Optical Coherence Tomography

Iannetti, Ludovico; Tortorella, Paolo; D'Ambrosio, Enzo; Spena, Rossela; Zito, Roberta; Gharbiya, Magda

doi:10.1155/2013/284821

Cited by 13 publications

(14 citation statements)

References 28 publications

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“…1e and f), or whether the external limiting membranes ( Fig. 1g and h) were disrupted or intact [19]. The OCT patterns were interpreted by two independent retinal specialists (F.I.M.…”

Section: Methodsmentioning

confidence: 98%

Correlation between visual acuity changes and optical coherence tomography morphological findings in idiopathic epiretinal membranes

Fang

Hsu

Chen

2015

Graefes Arch Clin Exp Ophthalmol

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In patients with idiopathic ERMs, the presence of CME and IS/OS disruption detected by OCT correlated with a poorer initial BCVA. Most patients' visual acuity remained stable during follow-up. The presence of CME with OCT represented a predictor of the progression of visual acuity. These results may provide valuable clinical information regarding the management of patients with idiopathic ERMs. We demonstrated that the presence of CME and IS/OS disruption detected with OCT correlated with a poorer BCVA in idiopathic ERMs. The visual acuity of most patients was stable during the follow-up period. The presence of CME in OCT represented a predictor of vision deterioration for patients with idiopathic ERMs.

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“…1e and f), or whether the external limiting membranes ( Fig. 1g and h) were disrupted or intact [19]. The OCT patterns were interpreted by two independent retinal specialists (F.I.M.…”

Section: Methodsmentioning

confidence: 98%

Correlation between visual acuity changes and optical coherence tomography morphological findings in idiopathic epiretinal membranes

Fang

Hsu

Chen

2015

Graefes Arch Clin Exp Ophthalmol

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“…In our study, 19 eyes (66%) had a history of either intermediate, posterior, or panuveitis. The association between increased CRT and worse VA in uveitic eyes is still not clear [ 26 , 27 ]. It has been speculated that the stronger traction generated by ERMs leads to a thickening of the central retina and consequent disruption of the ellipsoid zone [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

“…The association between increased CRT and worse VA in uveitic eyes is still not clear [ 26 , 27 ]. It has been speculated that the stronger traction generated by ERMs leads to a thickening of the central retina and consequent disruption of the ellipsoid zone [ 27 ]. The latter is one of the anatomical patterns that have been proposed to correlate lower VA, such as foveal ERM and focal ERM attachment [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Epiretinal Membrane in Patients with Uveitis

et al. 2022

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Purpose-To evaluate the anatomical and functional outcomes of vitrectomy and epiretinal membrane (ERM) peeling in patients with uveitis. Secondarily, we evaluated the effect of internal limiting membrane (ILM) peeling on surgical outcomes, and of surgery on uveitis activity and, thus, therapeutic regime. Methods-Bicentre, retrospective, interventional case series of 29 eyes of 29 consecutive patients affected by uveitis and ERM, that had undergone pars plana vitrectomy with ERM peel between 2012 and 2020, with a minimum postoperative follow-up (FU) of six-months. Demographic data, best-corrected visual-acuity (BCVA), clinical findings, intraoperative and postoperative complications, and macular optical-coherence-tomography scans were reviewed. Results-The mean (standard deviation) duration of follow-up was 32 (22) months. At six-month FU, mean central-retinal-thickness (CRT) significantly improved (from 456 (99) to 353 (86) microns; p < 0.001), and mean BCVA improved from 0.73 (0.3) to 0.49 (0.36) logMAR (p < 0.001), with only one (3%) patient experiencing worsening of vision. The rate of concomitant cystoid macular edema decreased from 19 (66%) eyes at presentation to eight (28%) eyes at final-FU (p = 0.003). Comparing eyes in which ILM peeling was performed in addition to ERM peeling only, BCVA or CRT reduction were comparable. Only a minority of six (21%) eyes had a worsening in uveitis activity requiring additional medications, whereas most patients resumed the same treatment (52%) or received less treatment (28%) (p = 0.673). Conclusions-Vitrectomy with ERM peeling led to favourable anatomical and functional outcomes in patients with uveitis regardless of whether the ILM is peeled or not. As in most patients, no activation of the uveitis requiring additional medications was noted, we do not recommend changes in anti-inflammatory/immunosuppressive therapy postoperatively.

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“… 139 A disrupted photoreceptor ISel band was associated with poor visual outcome in another study of patients with ERM secondary to uveitis. 140 …”

Section: Inner Segment Ellipsoid In Medical Retinal Diseasesmentioning

confidence: 99%

Photoreceptor inner segment ellipsoid band integrity on spectral domain optical coherence tomography

Saxena¹,

Srivastav²,

Cheung³

et al. 2014

OPTH

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Spectral domain optical coherence tomography cross-sectional imaging of the macula has conventionally been resolved into four bands. However, some doubts were raised regarding authentication of the existence of these bands. Recently, a number of studies have suggested that the second band appeared to originate from the inner segment ellipsoids of the foveal cone photoreceptors, and therefore the previously called inner segment-outer segment junction is now referred to as inner segment ellipsoidband. Photoreceptor dysfunction may be a significant predictor of visual acuity in a spectrum of surgical and medical retinal diseases. This review aims to provide an overview and summarizes the role of the photoreceptor inner segment ellipsoid band in the management and prognostication of various vitreoretinal diseases.

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Epiretinal Membranes in Patients with Uveitis: Morphological and Functional Analysis with Spectral Domain Optical Coherence Tomography

Cited by 13 publications

References 28 publications

Correlation between visual acuity changes and optical coherence tomography morphological findings in idiopathic epiretinal membranes

Correlation between visual acuity changes and optical coherence tomography morphological findings in idiopathic epiretinal membranes

Functional and Anatomical Outcomes of Pars Plana Vitrectomy for Epiretinal Membrane in Patients with Uveitis

Photoreceptor inner segment ellipsoid band integrity on spectral domain optical coherence tomography

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