Correlation between visual acuity changes and optical coherence tomography morphological findings in idiopathic epiretinal membranes

Fang, I-Mo; Hsu, Chih-Chao; Chen, Lili

doi:10.1007/s00417-015-3069-0

Cited by 29 publications

(20 citation statements)

References 35 publications

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“…Among morphological changes of the retina in idiopathic ERM patients observed in OCT, outer retinal integrity seems to be related to potential visual acuity. This is consistent with previous studies showing that ellipsoid zone or interdigitation zone is related to BCVA [ 7 8 9 10 11 12 ]. UCVA was not associated with outer retinal integrity, but was significantly correlated with CMT and inner retinal irregularity index.…”

Section: Discussionsupporting

confidence: 93%

“…In contrast, patients with retinal abnormalities typically showed more decreased UCVA even with mild refractive error. In most clinical studies, visual function has been measured by BCVA after correcting refractive errors, and BCVA showed good correlation with retinal status [ 7 8 9 10 11 12 ]. Few studies have focused on UCVA, and there is little study on the relationship between UCVA and retinal state.…”

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confidence: 99%

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Correlation between Uncorrected Visual Acuity and Macular Distortion in Idiopathic Epiretinal Membrane Patients

Lee

Park

Kim

2017

Korean J Ophthalmol

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PurposeTo evaluate the association between degree of retinal abnormalities and uncorrected visual acuity (UCVA) in idiopathic epiretinal membrane (ERM) patients with a small amount of refractive error.MethodsWe retrospectively reviewed 49 eyes (37 patients) of idiopathic ERM patients. We investigated the association between visual acuity and macular status (central macular thickness [CMT], outer retinal integrity score, and inner retinal irregularity index) that was assessed by optical coherence tomography using multiple linear regression analysis. We defined visual acuity difference (VAD) as the difference between UCVA and best-corrected visual acuity (BCVA). We divided patients into two groups according to VAD size and compared clinical characteristics between the two groups. We also investigated factors associated with VAD using multiple linear regression analysis.ResultsBCVA showed significant association with CMT and outer retinal integrity score, while UCVA showed significant association with CMT and inner retinal irregularity index. Patients with a large VAD showed a similar level of BCVA compared to the small VAD group (logarithm of the minimum angle of resolution [logMAR], large VAD group 0.11 ± 0.11 vs. small VAD group 0.13 ± 0.12, p = 0.585). However, UCVA was worse (logMAR, large VAD group 0.44 ± 0.14 vs. small VAD group 0.18 ± 0.14, p < 0.001) and inner retinal irregularity was higher (large VAD group 1.06 ± 0.04 vs. small VAD group 1.04 ± 0.03, p < 0.001) in patients with a large VAD. On multiple linear regression analysis, the absolute value of spherical equivalent (standardized coefficient β 0.521, p < 0.001) and inner retinal irregularity index (standardized coefficient β 0.448, p < 0.001) were significantly associated with VAD.ConclusionsUCVA was associated with inner retinal irregularity in idiopathic ERM patients with a mild degree of refractive error. Inner retinal irregularity was also associated with degree of VAD, suggesting that the effect of refractive error correction is greater in patients with more distorted retina.

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Section: Discussionsupporting

confidence: 93%

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confidence: 99%

Correlation between Uncorrected Visual Acuity and Macular Distortion in Idiopathic Epiretinal Membrane Patients

Lee

Park

Kim

2017

Korean J Ophthalmol

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“…Previous studies showed that ERM eyes with ME at baseline had worse presenting visual acuity and worse postoperative visual acuity than eyes without preoperative ME. 2,11,[15][16][17][18] We found that MME preoperatively was associated with a worse visual prognosis after ERM removal. We hypothesize that inner retinal cystic changes are an indirect sign of visual pathway impairment, which persists after the release of the macular traction.…”

Section: Discussionmentioning

confidence: 99%

Associated Factors and Surgical Outcomes of Microcystoid Macular Edema and Cone Bouquet Abnormalities in Eyes With Epiretinal Membrane

Cicinelli

Post

Brambati

et al. 2022

Retina

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“…Epiretinal membrane (ERM) is a common macular disease that may induce various degrees of blurred vision and metamorphopsia [1][2][3][4]. At an early stage, ERM is characterized by an abnormal retinal light reflex on fundoscopy with mild retinal thickening and no distortion of the retinal surface [5,6].…”

Section: Introductionmentioning

confidence: 99%

Association of macular choroidal thickness with optical coherent tomography morphology in patients with idiopathic epiretinal membrane

Fang

Chen

2020

PLoS ONE

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To compare macular choroidal thickness of idiopathic epiretinal membrane (ERM) and fellow eyes, and before and after vitrectomy in terms of the morphological features on spectral-domain optical coherent tomography (SD-OCT). Methods Eighty-four patients with unilateral idiopathic ERM were involved. Patients were categorized into: Group 1, ERM without membrane contraction; Group 2, ERM with membrane contraction and retinal folding; and Group 3, ERM with membrane contraction and macular edema. Twenty-two patients received surgical removal of ERM. Choroidal thickness was compared between ERM and fellow eyes, and before and after treatment. Results Mean choroidal thickness was significantly greater in ERM eyes than in fellow eyes (234.4 ± 22.5 vs 220.6 ± 20.8 μm; P<0.01). Group 1 (n = 20) showed no significant difference in choroidal thickness between ERM and fellow eyes. Eyes in Group 2 (n = 27) and Group 3 (n = 37) showed statistically significant differences in mean choroidal thickness between ERM and fellow eyes (229.6 ± 23.8 vs 220.8 ± 19.6 μm; 242.6 ± 27.8 vs 221.0 ± 21.8 μm, respectively; P<0.05). In Group 2 (n = 8) and Group 3 (n = 16), choroidal thickness in ERM eyes decreased significantly at 1 month and 6 months after surgery, compared with that before surgery (P<0.05 for all comparisons). Conclusions Membrane contraction contributed to the increase in choroidal thickness in idiopathic ERM patients. This finding may help to elucidate the pathophysiologic features of idiopathic ERM as well as the response to treatment in these patients.

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Correlation between visual acuity changes and optical coherence tomography morphological findings in idiopathic epiretinal membranes

Cited by 29 publications

References 35 publications

Correlation between Uncorrected Visual Acuity and Macular Distortion in Idiopathic Epiretinal Membrane Patients

Correlation between Uncorrected Visual Acuity and Macular Distortion in Idiopathic Epiretinal Membrane Patients

Associated Factors and Surgical Outcomes of Microcystoid Macular Edema and Cone Bouquet Abnormalities in Eyes With Epiretinal Membrane

Association of macular choroidal thickness with optical coherent tomography morphology in patients with idiopathic epiretinal membrane

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