Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis

Öztürk, Şule; Şahın, Mazlum

doi:10.21470/1678-9741-2019-0067

Cited by 4 publications

(4 citation statements)

References 15 publications

(16 reference statements)

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“…A similar correlation between the intima-media thickness of the carotid artery and Syntax score I and II was reported by the teams of Saedi et al, Ikeda et al, Aksu et al, and Korkmaz et al [27], [28], [29], [30]. The results of Ozturk and Sahin and Costanzo et al and col [31], [32], [33] are opposing. Despite the various incidences cited above, the combination of carotid and coronary atherosclerosis is an indisputable clinical fact.…”

Section: Discussionsupporting

confidence: 76%

Survival and Prognostic Factors After Carotid Artery Stenting in Patients with Concomitant Coronary Disease

Goranov

Tokmakova

Nikolov

2021

Open Access Maced J Med Sci

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AIM: The aim of the study was to analyze the prognostic factors in patients after carotid artery stenting (CAS). METHODS: In 329 patients after CAS, the median survival (MS) and overall survival (OS) were calculated for a follow-up period of 2–101 months. All patients underwent coronary angiography before carotid stenting and, if indicated, coronary revascularization. Four groups of factors were analyzed: Carotid disease, coronary artery disease (CAD), underlying cardiac pathology, and concomitant diseases. RESULTS: MS in all patients was 86 months, OS at 1, 3, 5, and 9 years was - 94%, 85%, 73%, and 51%, respectively. Event free survival was 85 months. Log Rank-Mantel-Cox analysis demonstrated significantly reduced MS in 21 tested factors, most of them related to CAD. Two-step multifactorial Cox regression analysis defined only 7 of them as independent prognostic factors for the survival of patients after CAS: Left main stenosis, complete revascularization, late myocardial infarction, stroke, age over 70 years, valvular disease, and carotid score. CONCLUSION: Survival of patients after CAS is limited mainly by CAD and underlying cardiac pathology. Staged revascularization treatment strategy may improve the prognosis and survival of patients with both carotid and coronary disease.

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Section: Discussionsupporting

confidence: 76%

Survival and Prognostic Factors After Carotid Artery Stenting in Patients with Concomitant Coronary Disease

Goranov

Tokmakova

Nikolov

2021

Open Access Maced J Med Sci

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“…SYNTAX score is widely used by interventional cardiologists and cardiothoracic surgeons to predict the severity/complexity of coronary artery disease and to determine the post-operative outcome of patients undergoing CABG or PCI. Literature from international centers shows favorable outcome of CABG if the Syntax score comes more than ≥34 [18][19][20]. In our study only 7.2% (n = 11) patients had Syntax score more than 34 and fall into high-risk Syntax score group while the majority had low (75.2%, n 115) and intermediate (17.6%, n = 27) risk Syntax score, respectively and when high-risk Syntax score patients were separately evaluated for correlation with HbA1c levels, we have observed an insignificant association.…”

Section: Discussionmentioning

confidence: 99%

Correlation of Glycosylated Hemoglobin and Complexity of Coronary Artery Disease among Aged ≥45 Years Population with Diabetes Mellitus

Memon

Kashif

Arain

et al. 2021

JPRI

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Objective: Cardiovascular diseases are 1.7 times more prevalent in patients with diabetes mellitus. The aim behind this study was to examine the correlation of glycosylated hemoglobin and complexity of coronary artery disease among middle aged population with diabetes mellitus Patients and Methods: This was a clinical prospective hospital-based comparative study carried out in the department of the cardiology department of Isra University Hospital Hyderabad for 10 months. 153 participants with diabetes mellitus having age ≥45 years both male and female and undergoing their first coronary angiography were included. Data were entered and analyzed by using Statistical Package for the Social Sciences version 21.0. Results: A total of 153 patients were finally analysed. Patients were divided into two groups; group I (HbA1c <6.5%, normal) and group II (HbA1c >6.5%, impaired). The mean age was slightly higher in group II 54.60 as compared to group I 53.65 years, respectively. The Syntax score was correlated with HbA1c levels in patients older than 45 years of age (r = 0.001; p >0.05). Moreover, the higher HbA1c levels were observed in every three categories of Syntax score but they were insignificantly associated with each other in patients with diabetes mellitus and having age more than 45 years. Conclusion: The HbA1c is insignificantly correlated with the complexity of coronary artery disease in diabetic patients having age more than 45 years. While only two factors, hypertension and increased triglycerides are significantly different among the HbA1c groups.

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“…Presence of CAS has been shown to be a significant risk factor for peri-post-operative stroke in patients undergoing CABG, with a prevalence of 3% in unilateral stenosis, 5% in bilateral stenosis, and 7% in total carotid occlusion. [10,31,32] Therefore, screening for CAS before CABG in patients with intermediate and high SS may be reasonable. In conclusion, we demonstrated that there was a proportional increase in the severity of CAS to CAD complexity using SS.…”

Section: Discussionmentioning

confidence: 99%

Karotis Arter Hastalığı Şiddeti ile Syntax Skoru Arasındaki İlişki

Erdoğan

Akdemir

Vatan

2021

Journal of Contemporary Medicine

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Introduction: Carotid artery disease may cause severe constriction or complete occlusion in carotid arteries, it may not give any symptoms until it appears. In some people, stroke is the first finding of the disease. One of the most important causes of stroke is carotid artery stenosis and atherosclerosis causes a total of one third of the stroke. Atherosclerosis; It is a specific finding of both coronary and carotid artery disease.The relationship between carotid atherosclerotic diasease and coronary artery disease (CAD) have been in previous reports Aim: In this study, we aimed to show the relationship between the severity of the carotid artery stenosis(CAS) determined by angiography and the anatomical complexity of CAD assessed by SYNTAX Score (SS). Material and Method:Our study was carried out in accordance with the Declaration of Helsinki Principles by obtaining the ethics committee approval dated 09.06.17 and numbered E.8640. A total of 45 patients with simultaneously carotid and coronary angiography performed were included in our study. SS, a marker of CAD complexity, was determined by dedicated computer software. The patients were divided into two groups according to the classification of SS: low SS (n=33, SS <22) and intermediate-high SS (n=12, SS ≥22) groups. The severity of CAS was assessed by digital subtraction angiography (DSA) of six distinct segments of the carotid artery included the left and right common, internal, and external carotid arteries. Spearman's correlation coefficients were used to determine the correlations between SS and CAS score. Results:The CAS severity score was significantly higher in patients with intermediate and high SS group than in the low SS group (3/4/4.75 vs. 1/2/3, p=0.001). There was also significant correlation between SS and CAS severity score (r=0.47, p=0.001). Conclusions:We revealed that there was a proportional increase in the severity of CAS to CAD complexity using SS. It may suggest that complex multivascular atherosclerotic disease is the systemic nature of atherosclerosis.

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Syntax Score I and II for Predicting Carotid Artery Stenosis in Patients with Multivessel Coronary Artery Disease: A Propensity Score Matching Analysis

Cited by 4 publications

References 15 publications

Survival and Prognostic Factors After Carotid Artery Stenting in Patients with Concomitant Coronary Disease

Survival and Prognostic Factors After Carotid Artery Stenting in Patients with Concomitant Coronary Disease

Correlation of Glycosylated Hemoglobin and Complexity of Coronary Artery Disease among Aged ≥45 Years Population with Diabetes Mellitus

Karotis Arter Hastalığı Şiddeti ile Syntax Skoru Arasındaki İlişki

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