<b><i>Background:</i></b> Parkinson’s disease (PD) is one of the most common neurological disorders, of insidious onset, with major motor symptomatology including bradykinesia, rest tremor, rigidity, and postural disturbances. Virtual reality (VR) and motor imagery (MI) are among the more innovative techniques for the rehabilitation of patients with PD which promote motor learning both through explicit and implicit processes. This study is unique in that it will examine the combined effects of VR and MI on motor function, balance and activities of daily living (ADLs) in patients with PD. <b><i>Objective:</i></b> The aim of this work is to investigate the effects of VR with MI techniques in addition to routine physical therapy on motor function, balance, and ADLs in patients with PD. <b><i>Methods:</i></b> This is a two-armed parallel design, single-blinded (assessor blinded), single-centered, randomized controlled trial, and the study protocol is based on SPIRIT guidelines. Thirty-four patients with PD (Modified Hoehn and Yahr stages I–III) will be randomly allocated with a 1:1 ratio into Group A (control group) and Group B (treatment group). Group A will be given routine physical therapy in 40-min sessions and 20 min of walking and cycling with a short period of rest, every alternate day (3 days per week) for 12 weeks, while for Group B routine physical therapy protocols along with VR and MI will be used in 60-min sessions, every alternate day (3 days per week) for 12 weeks. The primary outcome measures are as follows: (i) the Unified PD Rating Scale (UPDRS; part III), (ii) the Berg Balance Scale (BBS), and the Activities-Specific Balance Confidence Scale (ABC). The secondary outcome measure is the UPDRS (part II). Assessments will be recorded at baseline, the sixth and twelfth weeks of therapy, and 1 month after the discontinuation of therapy. <b><i>Clinical Study Registration:</i></b> This randomized controlled prospective study was registered with the Iranian Registry of clinical trials (IRCT20200221046567N1) on April 1, 2020 (https://www.irct.ir/trial/46073).
Objective The objective of the study was to evaluate the computer workstation settings and the prevalence of musculoskeletal (MSK) related problems in computer users of bank. Methods A cross-sectional study was conducted among100 computer users of State Bank of Pakistan, Faisalabad and National Bank of Pakistan, Faisalabad from March to December 2017. Inclusion criteria of the study were male and female bank workers, age between 25–60 years who use desktop computers for at least 3 h a day and had at least 6 months working experience. Cornell Musculoskeletal Discomfort Questionnaire (CMDQ) was used to determine prevalence of MSK problems while Rapid Office Strain Assessment (ROSA) tool was used to evaluate Computer Work-Station (CWS) ergonomic parameters. The data was analyzed by descriptive statistics and variant correlation using SPSS version 20. Results The mean CMDQ was higher (43.0 ±33.6) in female than male (16.9±20.8) and there was significant association between gender and total discomfort (P=0.001). The discomfort was higher among females then males. The body parts reported to have the most significant levels of discomfort was the neck and head (mean 3.595±7.49), lower back (2.75±5.39) and right shoulder (mean 2.15±4.32).About 40% subjects suffered from neck pain while the remaining body parts having discomfort were right shoulder (39%), left shoulder (37%), and low back (36%).Almost 90% of the participants had ROSA score greater than 5 that shows that most individuals were at higher risk of ergonomics hazardous. Conclusion The results of the present study demonstrated that MSK discomfort is common among computer users of bank employees and neck, shoulder and lower back region were at greater risk. MSK discomfort was higher in females. Workers are exposed to ergonomic hazards and need immediate improvement.
Background Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, impairing balance and motor function. Virtual reality (VR) and motor imagery (MI) are emerging techniques for rehabilitating people with PD. VR and MI combination have not been studied in PD patients. This study was conducted to investigate the combined effects of VR and MI techniques on the balance, motor function, and activities of daily living (ADLs) of patients with PD. Methods This study was a single-centered, two-armed, parallel-designed randomized controlled trial. A total of 44 patients of either gender who had idiopathic PD were randomly allocated into two groups using lottery methods. Both groups received Physical therapy (PT) treatment, while the experimental group (N: 20) received VR and MI in addition to PT. Both groups received assigned treatment for three days a week on alternate days for 12 weeks. The Unified Parkinson’s Disease Rating Scale (UPDRS) (parts II and III), Berg Balance Scale (BBS), and Activities-specific Balance Confidence (ABC) Scale were used as outcome measures for motor function, balance, and ADLs. The baseline, 6th, and 12th weeks of treatment were assessed, with a 16th week follow-up to measure retention. The data was analysed using SPSS 24. Results The experimental group showed significant improvement in motor function than the control group on the UPDRS part III, with 32.45±3.98 vs. 31.86±4.62 before and 15.05±7.16 vs. 25.52±7.36 at 12-weeks, and a p-value < 0.001. At 12 weeks, the experimental group's BBS scores improved from 38.95±3.23 to 51.36±2.83, with p-value < 0.001. At 12 weeks, the experimental group's balance confidence improved considerably, from 59.26±5.87to 81.01±6.14, with a p-value of < 0.001. The experimental group's ADL scores improved as well, going from 22.00±4.64 to 13.07±4.005 after 12 weeks, with a p-value of < 0.001. Conclusion VR with MI techniques in addition to routine PT significantly improved motor function, balance, and ADLs in PD patients compared to PT alone. Trial registration IRCT20200221046567N1. Date of registration: 01/04/2020
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