Karotis Arter Hastalığı Şiddeti ile Syntax Skoru Arasındaki İlişki

Abstract

Introduction: Carotid artery disease may cause severe constriction or complete occlusion in carotid arteries, it may not give any symptoms until it appears. In some people, stroke is the first finding of the disease. One of the most important causes of stroke is carotid artery stenosis and atherosclerosis causes a total of one third of the stroke. Atherosclerosis; It is a specific finding of both coronary and carotid artery disease.The relationship between carotid atherosclerotic diasease and coronary artery disease (CAD) have been in previous reports Aim: In this study, we aimed to show the relationship between the severity of the carotid artery stenosis(CAS) determined by angiography and the anatomical complexity of CAD assessed by SYNTAX Score (SS). Material and Method:Our study was carried out in accordance with the Declaration of Helsinki Principles by obtaining the ethics committee approval dated 09.06.17 and numbered E.8640. A total of 45 patients with simultaneously carotid and coronary angiography performed were included in our study. SS, a marker of CAD complexity, was determined by dedicated computer software. The patients were divided into two groups according to the classification of SS: low SS (n=33, SS <22) and intermediate-high SS (n=12, SS ≥22) groups. The severity of CAS was assessed by digital subtraction angiography (DSA) of six distinct segments of the carotid artery included the left and right common, internal, and external carotid arteries. Spearman's correlation coefficients were used to determine the correlations between SS and CAS score. Results:The CAS severity score was significantly higher in patients with intermediate and high SS group than in the low SS group (3/4/4.75 vs. 1/2/3, p=0.001). There was also significant correlation between SS and CAS severity score (r=0.47, p=0.001). Conclusions:We revealed that there was a proportional increase in the severity of CAS to CAD complexity using SS. It may suggest that complex multivascular atherosclerotic disease is the systemic nature of atherosclerosis.