Impacto das malformações congênitas na mortalidade perinatal e neonatal em uma maternidade-escola do Recife

Amorim, Melania Maria Ramos; Vilela, Paulo Carvalho; Santos, Aleksana Regina Viana Dutra; Lima, Ana Luíza Medeiros Vasconcelos de; Melo, Eduardo França Pessoa de; Bernardes, Hildenice Ferreira; Filho, Paulo Fernando Bezerra de Menezes; Guimarães, Vilma

doi:10.1590/s1519-38292006000500003

Cited by 40 publications

(53 citation statements)

References 15 publications

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“…In addition, they signifi cantly contribute to embryonic and fetal death, they are among the causes that lead to loss of potential years of life, and they are also responsible for three quarters of the population's physical handicaps. 7,8,9 As the child mortality rate from infectious, parasitic and respiratory diseases decreased, there was an increase in BD's relative participation in child deaths. This is because, as other causes of death are controlled, BDs begin to play a proportionately more important role.…”

Section: Introductionmentioning

confidence: 99%

Avaliação das declarações de nascido vivo como fonte de informação sobre defeitos congênitos

Geremias

Almeida

Flores

2009

Rev. bras. epidemiol.

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OBJETIVO: Estimar a prevalência de defeitos congênitos (DC) em uma coorte de nascidos vivos (NV) vinculando-se os bancos de dados do Sistema de Informação de Mortalidade (SIM) e do Sistema de Informação sobre Nascidos Vivos (SINASC). MÉTODOS: Estudo descritivo para avaliar as declarações de nascido vivo como fonte de informação sobre DC. A população de estudo é uma coorte de NV hospitalares do 1º semestre de 2006 de mães residentes e ocorridos no Município de São Paulo no período de 01/01/2006 a 30/06/2006, obtida por meio da vinculação dos bancos de dados das declarações de nascido vivo e óbitos neonatais provenientes da coorte. RESULTADOS: Os DC mais prevalentes segundo o SINASC foram: malformações congênitas (MC) e deformidades do aparelho osteomuscular (44,7%), MC do sistema nervoso (10,0%) e anomalias cromossômicas (8,6%). Após a vinculação, houve uma recuperação de 80,0% de indivíduos portadores de DC do aparelho circulatório, 73,3% de DC do aparelho respiratório e 62,5% de DC do aparelho digestivo. O SINASC fez 55,2% das notificações de DC e o SIM notificou 44,8%, mostrando-se importante para a recuperação de informações de DC. Segundo o SINASC, a taxa de prevalência de DC na coorte foi de 75,4%00 NV; com os dados vinculados com o SIM, essa taxa passou para 86,2%00 NV. CONCLUSÕES: A complementação de dados obtida pela vinculação SIM/SINASC fornece um perfil mais real da prevalência de DC do que aquele registrado pelo SINASC, que identifica os DC mais visíveis, enquanto o SIM identifica os mais letais, mostrando a importância do uso conjunto das duas fontes de dados.

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Section: Introductionmentioning

confidence: 99%

Avaliação das declarações de nascido vivo como fonte de informação sobre defeitos congênitos

Geremias

Almeida

Flores

2009

Rev. bras. epidemiol.

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“…High rates were also observed in other Brazilian centers, as reported in a recent study of the Brazilian Network on Neonatal Research. 19 The high rates of newborns with congenital malformations, increased in the second period, are higher than those reported in other studies, 22 25 Results presented in this and in other reports point to the need to monitor all the perinatal population in Brazil, where perinatal morbidity and mortality rates are still high, even for gestations of potentially low perinatal risk, including the most developed regions of the country. 26,27 Therefore, the importance of standardized information records of basic variables for all the newborn population during health care services, and not only for newborns < 1,500 g or with gestational age < 34 weeks, is stressed.…”

Section: Total Birthsmentioning

confidence: 58%

Avaliação do perfil de nascimentos e óbitos em hospital de referência

Rego¹,

França²,

Travassos³

et al. 2010

J. Pediatr. (Rio J.)

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Objective: To compare perinatal health indicators in a referral hospital in Belo Horizonte, Brazil. Methods:Perinatal results and indicators of single live births in Hospital das Clínicas of Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil, were compared for two periods, 1995-1998 and 2003-2006. The chi-square test and Student's t test were applied with 5% significance level and 95% confidence interval. Data were obtained from the Perinatal Information System (Sistema Informático Perinatal, SIP), Latin American Center for Perinatology (Centro Latinoamericano de Perinatología, CLAP), Pan American Health Organization (PAHO), Hospital das Clínicas, and from medical records. Results:Mothers were approximately 26 years old on average. The number of prenatal appointments had an average increase of one appointment, regardless of birth weight, and there was a significant decrease in the number of caesarean deliveries in the second period. The average gestational age was 38 weeks in both periods, with a high rate of premature births (17.0 and 16.7%, respectively). The rate of newborns < 2,500 g was high in both periods (17.6 and 16.6%, respectively) with a decrease in the rate of newborns considered small for their gestational age. When congenital malformations were excluded, early neonatal mortality risk decreased from 12.4 per 1,000 live births in the first period to 8.0 per 1,000 live births in the second period, with considerable decrease for newborns with gestational age < 34 weeks.Conclusions: Important differences were verified concerning health care assistance procedures and perinatal results, and they are compatible with the global improvement in neonatal health observed in the 2003-2006 period. However, the persistence of unfortunate neonatal incidents that can be reduced with the use of available perinatal technologies reveals the need for constant monitoring of perinatal hospital care for all groups of newborns.J Pediatr (Rio J). 2010;86(4):295-302: Health services evaluation, information systems, neonatal mortality, infant mortality.

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“…2.7% among live newborns (NB) and 6.7% among stillbirths. Among the causes of death, neonatal malformations are the second most common reason, the fi rst one being prematurity 2 .…”

Section: Introductionmentioning

confidence: 99%

Characteristics of the clinical development of a newborn with gastroschisis in an intensive care unit in latin america

Redondo¹,

Feferbaum

Vieira

et al. 2016

J. Hum. Growth Dev.

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Introduction: Congenital malformations are major diseases observed at birth. They are the second most common cause of death in the neonatal population, the fi rst one being prematurity.Objective: To characterise the clinical outcome of newborns with gastroschisis (GS) in a neonatal intensive care unit. Methods:A retrospective observational clinical study in 50 infants with GS using the association of intestinal abnormalities, impossibility of primary closure of the abdominal defect and reoperation necessity as classifi cation criteria for the disease. The signifi cance level was p < 0.05. Results:The hospitalisation to primary surgery occurred with a median age of 2 hours. Fourteen percent of children were subjected to a primary silo interposition and 24% had associated intestinal malformation. Nineteen newborns (NB) required more than one surgery. The median length of stay was 33 days, higher in patients with complex GS (56 days). All NB recovered from urine output 48 hours after surgery and 40% had hyponatraemia and oligoanuria in this period. There was no difference between the natraemia and fasting time (p = 0.79). Weight gain was similar in both groups with total parenteral nutrition and became signifi cantly higher in patients with simple GS after enteral feeding (p = 0.0046). These NB evolved 2.4 times less cholestasis. Late-onset sepsis occurred in 58% of patients and was related to the infection of the central venous catheter in 37.9% of cases. Mortality was higher in infants infected with complex GS and the overall mortality rate was 14%. Conclusion:Clinical characterisation of newborns with gastroschisis depends on the complexity and the knowledge and conduct of morbidities to reduce mortality.Key words: gastroschisis, new-born, mortality, total parenteral nutrition, renal insuffi ciency, infection. INTRODUCTIONCongenital malformations are major diseases observed at birth. In the United States, a prevalence of about 3% 1 is cited. In Brazil, a study at the Fernandez Figueira Institute in Rio de Janeiro found that the prevalence was similar, i.e. 2.7% among live newborns (NB) and 6.7% among stillbirths. Among the causes of death, neonatal malformations are the second most common reason, the fi rst one being prematurity 2 .Gastroschisis (GS) is a congenital malformation of the abdominal wall that has increased in prevalence worldwide; its causes have not been fully elucidated 3 . In the 1960s, the prevalence of this disease was 1:50,000 live births. However, Kirby et al. 4 - -Characteristics of the clinical development of a newborn with gastroschisis in an intensive care unit in latin america J Hum Growth Dev. 2016; 26(2): 190-198 DOI: http://dx.doi.org/10.7322/jhgd.119266 temporal increase of 2.23 per 10,000 live births to 4.42 per 10,000 Regarding the defi nition of live births. The current prevalence in South America is 2.9:10,000 5 . This disease is characterised by a defect in abdominal wall closure with herniation of the intestines and other abdominal organs into the amniotic cavity. ...

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Impacto das malformações congênitas na mortalidade perinatal e neonatal em uma maternidade-escola do Recife

Cited by 40 publications

References 15 publications

Avaliação das declarações de nascido vivo como fonte de informação sobre defeitos congênitos

Avaliação das declarações de nascido vivo como fonte de informação sobre defeitos congênitos

Avaliação do perfil de nascimentos e óbitos em hospital de referência

Characteristics of the clinical development of a newborn with gastroschisis in an intensive care unit in latin america

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