Production of polymeric nanofibers with different conditions of the electrospinning process

Abstract

Nanofibers are materials that present high elasticity, strength, porosity and surface-area-to-volume ratio. The electrospinning method is the most widely adopted technique for forming polymeric nanofibers due to repeatability, easy scale-up process and production of long and continuous nanofibers. This method produces nanofibers with diameters ranging from 10 nm to 1000 nm. The process is regulated by many parameters which significantly affecting the morphology of the nanofibers, and through the proper handling of these parameters are obtained desired nanofibers in morphology and diameters. Based on this, the objective of this work was to evaluate the size and morphology of nanofibers obtained by different conditions of the electrospinning process. The electrospinning technique will be utilized to produce nanofibers with polyacrylonitrile (PAN) polymer and solvent N, N-dimethylformamide (DMF). The polymer solutions (10% (w/v)) were injected through of the capillary with diameter 0.45; 0.55; 0.70 and 0.80 mm. The distances from the collector to the capillary were tested between 100 and 200 mm, voltage between 15 and 25 kV, and feed rate of the solution between 100 and 1000 µL/h. All of the tests were conducted at 22 °C with the relative humidity level controlled at 65±1%. The morphology and size of nanofibers were evaluated by Scanning Electron Microscopy (SEM). Thus, the development of nanofibers with small diameter and high pore volume facilitate bioactive molecules loading and / or transport of nutrients and wastes, and allow the polymeric nanofibers become important class of biomaterials.

A new thermal protective clothing design with silica aerogel filled acrylic nanofibers

“…Hydrophobic silica aerogel was used to make the membrane waterrepellent since thermal protective clothing may be exposed to hot water and toxic liquids. All fabric combinations are given in Table 1. 2.2 PAN/silica aerogel membrane production First, 6 wt % PAN and 5 wt % silica aerogel were separately dissolved in DMF with stirring at room temperature for 24 h (Vaz et al, 2017). Then, PAN/silica aerogel solutions with different silica aerogel content were obtained by mixing the prepared PAN and silica aerogel solutions at different volume ratios given in Table 2.…”

“…First, 6 wt % PAN and 5 wt % silica aerogel were separately dissolved in DMF with stirring at room temperature for 24 h (Vaz et al. , 2017).…”

Influencia de los parámetros de electrohilado en la morfología y tamaño de fibras de fibroína de seda

“…La influencia de los parámetros de proceso individuales (campo eléctrico, flujo y distancia), así como sus interacciones, en el diámetro medio de las fibras obtenidas, fueron estudiadas por medio de un análisis de varianza (ANOVA). Para las variables que mostraron diferencias significativas se realizó comparaciones por pares de sus medias usando la prueba Tukey [7,8]. Las diferencias se consideraron estadísticamente significativas para valores P <0.05.…”

Metronidazole- and Amoxicillin-Loaded PLGA and PCL Nanofibers as Potential Drug Delivery Systems for the Treatment of Periodontitis: In Vitro and In Vivo Evaluations

“…Electrospinning is the most commonly used and efficient method for the preparation of nanofibers, and it has been applied at industrial and laboratory scales. It generally consists of a syringe pumping a polymer solution, a high voltage electric reservoir, and a conductive rotating collector [20,[26][27][28]. Electrospinning has been used in the preparation of electrospun PLGA fibers for the local release of metronidazole in the treatment of periodontitis [29].…”