Enxerto autólogo de pele, em malha, com espessura completa, na reparação de feridas carpometacarpianas de cães: resposta à irradiação laser AsGa

Paim, Carlos Breno Viana; Raiser, Alceu Gaspar; Cardoso, Ewerton; Beck, Cristiane

doi:10.1590/s0103-84782002000300014

Cited by 7 publications

(6 citation statements)

References 12 publications

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“…PBM has already demonstrated beneficial results when used in skin grafts . Previous studies had similar results to this study, PBM presenting satisfactory results related to graft viability, such as the percentage decrease in tissue contraction.…”

Section: Discussionsupporting

confidence: 85%

Photobiomodulation Increases Viability in Full‐Thickness Grafts in Rats Submitted to Nicotine

Souza¹,

Souza²,

Garcia³

et al. 2019

Lasers Surg Med

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Background and Objectives Photobiomodulation (PBM) therapy with 830 nm wavelength or 660 wavelength to compare the effects with parameters of 30 mW, 0.028 cm2, 9.34 seconds, and 3.64 J on the total integration of total skin grafts in rats submitted to nicotine. Study Design/Materials and Methods Sixty male Wistar rats were divided in six groups: Sham—skin‐grafting surgery; 830 nm—skin‐grafting followed by 830 nm irradiation; 660 nm—skin grafting followed by 660 nm irradiation; Nicotine—subjected to subcutaneous nicotine injection (2 mg/kg twice a day for 4 weeks), followed by skin grafting; Group Nicotine/830 nm—similar to Group Nicotine, followed by 830 nm irradiation; Group Nicotine/660 nm—similar to Group Nicotine, followed by 660 nm irradiation. The percentage contraction of the grafting tissue was evaluated through ImageJ®. The thickness of the epidermis, inflammatory infiltrates, and the space between the implanted tissue and receptor bed were determined by histology; and the expression of vascular growth factor and blood vessel density (factor VIII) were evaluated by immunohistochemistry. Results The PBM at both wavelengths promoted a facilitating effect on the integration of the skin graft under nicotine and had a more significant effect on the thickness of the epidermis and expression of angiogenesis without nicotine at a wavelength of 830 nm. Different wavelengths influence responses related to the viability of cutaneous grafts in rats submitted to nicotine. Conclusions The PBM with 830 nm and 660 nm promoted beneficial results in skin grafts submitted to the deleterious action of nicotine. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.

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Section: Discussionsupporting

confidence: 85%

Photobiomodulation Increases Viability in Full‐Thickness Grafts in Rats Submitted to Nicotine

Souza¹,

Souza²,

Garcia³

et al. 2019

Lasers Surg Med

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“…In all animals of both groups, dressings were applied in the immediate postoperative period, changed on the third, seventh and 15th days, and evaluated by blind observer with regard to the cicatrization aspect (e.g., exudate, colour, oedema) 23 . At the end of this period, the surgical site was macroscopically evaluated to monitor the development of a possible recurrence through the use of PRP.…”

Section: Methodsmentioning

confidence: 99%

Skin graft associated with platelet-rich plasma in correcting extensive injuries resulting from the resection of skin cancer chemically induced in rats

et al. 2021

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Purpose: To evaluate whether using platelet-rich plasma (PRP) in the graft recipient bed after the resection of a neoplasia can influence its recurrence because this product stimulates angiogenesis, mitogenesis and chemotaxis. Methods: A study with 30 rats Wistar ( Rattus norvegicus albinus ), which were separated into group A (induction of carcinogenesis, PRP in the postoperative period) and group B (induction of carcinogenesis, absence of PRP in the postoperative period), with 15 animals in each. Carcinogenesis was induced on the skin of the animals’ chest by the topical application of 0.5% dimethylbenzantracene (DMBA) diluted in acetone. After surgical resection of the induced neoplasia, PRP was used to stimulate angiogenesis before surgical wound synthesis. Data on the control and experimental groups and macroscopic and microscopic variables were evaluated using analysis of variance and the Tukey’s test (5%). Results: It was possible to determine that the use of PRP is good in reconstructive surgeries, but it is contraindicated in patients during tumor resection, as it can cause changes in the surgical bed, in addition to stimulating recurrences and metastases. Conclusions: PRP may interact with tumour cells that were in the recipient site of the surgical wound during the resection of a neoplasia, and a local recurrence process can be triggered by applying this product.

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“…Avaliando a ação do LBP no pega do enxerto cutâneo autólogo em cães, um grupo de estudo observou a presença de coloração rosada mais precoce nos enxertos irradiados. Atribuíram isso ao efeito bioestimulador do laser que provoca estímulo microcirculatório, além de, possivelmente, permitir que as reanastomoses vasculares ocorressem a partir de 24 horas após a cirurgia [14].…”

Section: Pub 904unclassified

Uso do Laser ALGaInP na cicatrização de lesões cutâneas experimentais em coelhos

Beheregaray

Gianotti

Leal

et al. 2018

Acta Scientiae. Vet.

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Background: Animals with extensive cutaneous lesions remain hospitalized for long periods. In addition to increasing treatment costs, this also causes stress in these animals. Low-power laser is widely used to support tissue repair processes. Its use in the treatment of cutaneous wounds has been studied, as it reduces the wound healing period and the consequences caused by the lesion. The study aimed to evaluat the wound healing process of experimental cutaneous wounds in rabbits with the use of laser therapy. Materials, Methods & Results:Ten healthy New Zealand rabbits were used in the study, which were divided in two groups (n=5). Skin biopsies were carried out on day 16 in Group 1 and on day 8 in Group 2. The animals were under general anesthesia for the experimental cutaneous lesion to be carried out. Two 1cm 2 wounds were made on the back of each animal. The lesions were measured by a pachymeter in the immediate postoperative period, then covered with sterile gauze and maintained with rubber bandages. The animals were treated only with Tramadon 3 mg.kg -1 twice a day, during 3 days. Only the lesions on the right side of the animals were irradiated regularly, on each side of the wound, at a distance of 0.5 cm from the margin. The equipment used was a 660nm wavelength AlGaInP laser diode (Laserpulse, Ibramed), pulsed at a frequency of 20 Hz, at a dose of 3J and stimulation time of 12s. The left-side lesions represented the control and the treatment administered to them consisted only of a cleanse using a NaCl solution at 0.9% once a day. The measurement of the lesion area was made every two days with a pachymeter, and the macroscopic characteristics were noted on a control card. For the histological evaluation of the wound healing process, biopsy specimens were taken from the right and left lesions on the sixteenth day in G1 and on the eighth day in G2, by means of a 6mm punch. The samples were stained with Hematoxylin-eosin for the global evaluation of the tissue section, and with Masson's trichrome for evaluation of the presence of collagen fibers in interstitial fibrosis sites. Hyperemia followed by a discreet bleeding could be observed in wounds treated with laser after its application. With regard to the wound healing area, there was no difference between treated and control animals in both groups. However, in the microscopic evaluation of G1, in relation to the histological variables, significantly higher results were found in lesions treated with laser however, in the microscopic evaluation of G1, in relation to the histological variables, significantly higher results were found in lesions treated with laser: vascular proliferation, fibroblast and collagen proliferation, as well as the presence of hair follicles. In G2, only the fibroblastic proliferation showed a significant difference (p= 0.08) in lesions treated with laser. Discussion: There was no difference in the number of inflammatory cells in this study, perhaps because the control animals underwent laser treatment of the contralateral lesion. H...

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Enxerto autólogo de pele, em malha, com espessura completa, na reparação de feridas carpometacarpianas de cães: resposta à irradiação laser AsGa

Cited by 7 publications

References 12 publications

Photobiomodulation Increases Viability in Full‐Thickness Grafts in Rats Submitted to Nicotine

Photobiomodulation Increases Viability in Full‐Thickness Grafts in Rats Submitted to Nicotine

Skin graft associated with platelet-rich plasma in correcting extensive injuries resulting from the resection of skin cancer chemically induced in rats

Uso do Laser ALGaInP na cicatrização de lesões cutâneas experimentais em coelhos

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