Nectandra Rol. ex Rottb. (Lauraceae) no Mato Grosso do Sul, Brasil

Alves, Flávio Macêdo; Sartori, Ângela Lúcia Bagnatori

doi:10.1590/s0102-33062009000100015

Cited by 9 publications

(12 citation statements)

References 18 publications

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“…2000 ; Pott et al. 2006 ; Alves and Ishii 2007 ) and stand out among the eight species of Nectandra occurring in semi-deciduous and tropical alluvial Brazilian rainforests (Alves and Sartori 2009 ).…”

Section: Resultsmentioning

confidence: 99%

In Vitro antileishmania activity of sesquiterpene-rich essential oils from Nectandra species

Bosquiroli

Ferreira

Farias

et al. 2017

Pharmaceutical Biology

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Context: New antileishmanias are needed because of toxicity, high cost and resistance problems associated with available drugs. Nectandra (Lauraceae) produces several classes of compounds but its essential oil has not previously been reported to have antileishmania activity.Objective: We evaluated the cytotoxicity and antileishmania activity of essential oils from Nectandra amazonum Nees, N. gardneri Meisn., N. hihua (Ruiz & Pav.) Rohwer and N. megapotamica (Spreng.) Mez.Materials and methods:Nectandra oils were extracted from stem bark/leaves by hydrodistillation and compounds were identified by GC-MS. Oils were tested against Leishmania infantum and L. amazonensis intracellular amastigotes and nitric oxide production was evaluated. Cytotoxicity was achieved on NIH/3T3 and J774.A1 cells for the selectivity index (SI).Results and discussion:Nectandra gardneri was active against L. infantum and L. amazonensis (IC50 = 2.7 ± 1.3/2.1 ± 1.06 μg/mL) and contained 85.4% sesquiterpenes, of which 58.2% was intermediol. Besides low cytotoxicity (SI >11.3), N. gardneri induced a significant increase in NO production by L. infantum-infected macrophages. Nectandra hihua had the best activity on L. infantum amastigotes (IC50 = 0.2 ± 1.1 μg/mL). This oil was 89.0% sesquiterpenes, with 28.1% bicyclogermacrene. The two specimens of N. megapotamica had different activities on amastigotes. The one richer in sesquiterpenes (49.9%) was active against both species (IC50 = 12.5 ± 1.4/21.3 ± 1.2) and had phenylpropanoid E-asarone as the main compound (42.4%). Nectandra amazonum showed moderate activity on both the species (IC50 = 31.9 ± 2.0/22.1 ± 1.3 μg/mL) and low selectivity (0.9 < SI >2.6), probably due to the major presence of β-caryophyllene (28.5%).Conclusions: Our data identify compounds that can now be isolated and used for the development of new antileishmanias.

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Section: Resultsmentioning

confidence: 99%

In Vitro antileishmania activity of sesquiterpene-rich essential oils from Nectandra species

Bosquiroli

Ferreira

Farias

et al. 2017

Pharmaceutical Biology

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“…Mez, ocorre de São Paulo ao Rio Grande do Sul, em quase todas as formações florestais, com altura de 15-25 m e tronco de 40-60 cm de diâmetro, enquanto que a espécie N. hihua (Ruiz e Pav.) Rohwer apresenta árvores de até 14 m de altura e possui a mais ampla distribuição geográfica do gênero (Alves & Sartori, 2009).…”

Section: Resultsunclassified

Ocorrência de Drepanoconis larviformis infectando espécies de Lauraceae no Mato Grosso do Sul, Brasil

Carvalho

Gavassoni

Pontim

et al. 2017

RCA

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“…Two of the indicator species of the rainy season, P. fuligineum and I. affinis are also reported as species of gallery forest (Flora do Brasil under construction, PMCG 2008), the latter is also important in the Vereda bottom zones (Araújo et al 2002. Nectandra gardneri is reported as a species from floodable forests of Cerrado (Alves & Sartori 2009).…”

Section: Discussionmentioning

confidence: 99%

Seasonal Diversity Of vegetation Structure Of veredas, Mato Grosso Do Sul, Brazil

et al. 2019

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Environmental Protection Area Guariroba is an area to protect the headwaters of a creek formed by streams of Veredas, generating the main water supply of municipality of Campo Grande, state of Mato Grosso do Sul, Brazil. Some degraded areas have to be restored; thus, it is important to investigate species composition and variations of the vegetation. Our objective was to evaluate the seasonal variation of the vegetation structure of Veredas within the hydrographic sub-basin. We estimated species cover in five points, each one with 0.5 x 0.5 m plots along 50 m transects on the five stream banks in two seasonal periods. We found 134 species from 95 genera and 49 families. In both seasons, Poaceae, Cyperaceae and Asteraceae were the richest families and the richest genera were Eleocharis (N = 6), Rhynchospora and Utricularia (N = 4). Species richness varied between Veredas, from 31 to 70. We found 41 species exclusive to the rainy season and 38 to the dry season. The analyses identified seven indicator species for the dry season and ten for the rainy season. There are seasonal differences in floristic composition and vegetation cover. Thus, the dynamics of water availability in Veredas, which is related to seasonality, is necessary for the maintenance and functioning of these habitats, which have an important role in local flora, fauna and water availability for the municipality.

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Nectandra Rol. ex Rottb. (Lauraceae) no Mato Grosso do Sul, Brasil

Cited by 9 publications

References 18 publications

In Vitro antileishmania activity of sesquiterpene-rich essential oils from Nectandra species

In Vitro antileishmania activity of sesquiterpene-rich essential oils from Nectandra species

Ocorrência de Drepanoconis larviformis infectando espécies de Lauraceae no Mato Grosso do Sul, Brasil

Seasonal Diversity Of vegetation Structure Of veredas, Mato Grosso Do Sul, Brazil

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