Резекция почки минимально-инвазивным способом является «золотым стандартом» в лечении злокачественных опухолей I стадии. На сегодняшний день существует большое количество методик выполнения резекции почки. Желание разработать техник у операции, которая бы включала все положительные характеристики и не имела ограничений в использовании, привело к созданию нормотонической резекции почки без ишемии.
The true causes of sexual disorders after radiation treatment of prostate cancer, among which the central role is occupied by erectile dysfunction, are still not fully clarified. The number of patients who undergo various radiation-exposure options as a radical therapy is steadily increasing, which makes the issue very relevant. This literature review provides up-to-date data on the most studied probable mechanisms of the erectile function status decline after radiation therapy for prostate cancer.
In recent years, significant changes have taken place in the treatment of prostate cancer. Modern radiation treatment technologies are beginning to take a leading position not only in localized and locally-advanced forms of the disease, but also in the case of oligometastatic process. This encourages a natural interest in various aspects of radiation therapy of prostate cancer, in particular its effects on erectile function status. Analysis of domestic literature shows the complete absence of publications on the technical possibilities of radiation therapy to preserve potency after treatment. The purpose of this work was to highlight this critical issue.
This article discusses the main approaches to performing laparoscopic partial nephrectomy. For the method using warm ischemia, the main studies related to the time of warm ischemia and its effect on renal function have been analyzed. The basic techniques for operations united by the general name zero ischemia kidney resection are also considered. The main positive and negative aspects of induced hypotension are described. The article presents the authors’ own experience in performing normotonic laparoscopic partial nephrectomy.
Контакты: Эльдар Мухамедович Мамижев mamijev@mail.ru В представленном обзоре литературы рассмотрены исследования, основной целью которых было распределить опухоли мочевого пузыря по молекулярным подтипам. Схожая классификация давно активно используется при лечении рака молочной железы. К основополагающим работам в области молекулярных подтипов рака мочевого пузыря относятся исследования группы Lund, проект TCGA (The Cancer Genome Atlas), исследования MD Anderson. Также мы включили данные о попытках применения молекулярной таксономии рака мочевого пузыря в лечении. Ключевые слова: рак мочевого пузыря, молекулярный подтип, лечение рака мочевого пузыря, иммуногистохимия Для цитирования: Осетник В.К., Мамижев Э.М., Джалилов И.Б. и др. Молекулярные подтипы рака мочевого пузыря и первые успехи в персонализированном лечении. Онкоурология 2020;16(1):106-13.In the literature review we described studies, the main purpose of which was to distribute bladder tumors by molecular subtypes. A similar classification has long been actively used in the treatment of breast cancer. The pioneering work in the molecular subtypes of bladder cancer includes the work by Lund group, the TCGA (The Cancer Genome Atlas) project, the MD Anderson study. We have also included data on attempts to apply molecular taxonomy of bladder cancer in treatment.
Patients who practice Islam often refuse the proposed type of treatment for malignant neoplasms, citing religious reasons. Most fear that complete or partial non-retention of urine, the presence of a urostoma (ileal conduit) will violate their ritual purity and, as a result, their religious duties. The consequence of such refusal of treatment may be a lower quality of life, compared with patients of other faiths. Unfortunately, a low awareness of religious responsibilities among surgeons performing pelvic exentesis, cystectomy, prostatectomy, may prevent a full-fledged discussion of these issues before surgery. The presented review of the literature examined studies, legal aspects, and religious arguments that assist doctors in choosing treatment tactics for patients.
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