The aim of this work is to review and analyze the data published in the modern scientific literature obtained in pharmacological, pharmacognostic and pharmacotechnological studies of various types of raw materials obtained from members of the family Lamiaceae L., which were sources of biologically active substances, pharmaceutical substances, total extracts and the drugs – with a neurotropic activity.Materials and methods. For the review, we used the information of scientific literature from open and accessible sources of the last twenty years, located in the scientific and technical libraries of institutions, as well as in electronic databases: Elibrary, PubMed, Scopus, Cyberleninka, GoogleAcademy, J-Stage. The search inquiries were: the species of the family Lamiaceae (Russian and Latin), the samples of medicinal plant materials based on them as well as the names of the drugs and biologically active substances obtained from these raw materials.Results. When working with the sources of scientific information, the main attention was paid to pharmacologic tests performed during the studies on laboratory animals and proving the presence of neurotropic activity in the studied objects – essential oils and extracts from plant raw materials: aqueous, aqueous alcoholic, and methanol ones. It has been established that the potential of the therapeutic and preventive application of pharmaceutical substances and drugs based on the medicinal plant materials obtained from 30 genera members of the Lamiaceae family, remains unrealized despite the close attention of various researchers.Conclusion. This review comprised 71 species from 30 genera. Despite the significant level of the previous study presented in the analysis of this publication, an enormous potential of this family’s species remains unexplored. In the future, they can be of both – pharmacognostic and practical interest, in particular, in creation of new medicinal preparations of the neurotropic action based on them.
The technology that is elaborated is to grow purple cone-flower (Echinacea Purpurea L.) producing appropriate roots and rhizomes that can be used to obtain at the same time the additional output in the substance of juice from both the foliage and dry plants. Optimal results on yield and quality of additional output were achieved when the plants were rejuvenated at the stage of budding.
Aim. The study of the phenology and seed productivity of golden root plants in the 2nd‐4th years of life in the Moscow region under the influence of meteorological conditions. Methods. The objects of research were plants of golden root from the biocollection of VILAR in Moscow. The studies included field and laboratory experiments, which conducted in 2016‐2019 according to methods adopted in medicinal plant production. Weather conditions in the Moscow region during the research period were identified on the Internet. Seed productivity was assessed according to generally accepted methods. Determination of seed sowing qualities was carried outaccording to National Standard 34221‐2017.Results. The influence of weather conditions on the passage of phenological phases of young golden root plants in 2016‐2019 in the Non‐chernozem zone of the Russian Federation under experimental field conditions was studied for the first time. The duration of phenological phases depending on conditions in the year of observation was determined. The composition of the population of young golden root plants for the second, third and fourth years of vegetation wasestablished. Adverse factors which reduce seed productivity and affect the quality of seeds were identified.Conclusion. The favourable meteorological characteristics of the growing season contributed to an increase in the mass of 1000 seeds by an average of 43 mg and increased seed germination to 82%. Differences in seed quality and productivity of seeds depending on the conditions of the year of observation may indicate the necessity for measures for adaptation of the plants to harmful environmental factors.
Nepetae catariae herba is used in the Russian Federation as spice. The chemical compounds of herb have been studied. This plant has been introduced into the culture. There are its domestic varieties. The fruits of the plant accumulate up to 25% of fatty oil and contain specific laballenic acid, which has a wide range of antimicrobial and fungicidal actions. The yield of fruit crops is 5–6 c/ha.The aim is to study some criteria for the standardization of the quality of Nepetae catariae herb as a new medicinal plant raw material.Materials and methods. The studied fruits are from the biological collection of Federal State Budgetary Institution of All – Russia Research Institute of Medicinal and Aromatic Plants. Binocular magnifier brand MBS-10 and Axioplan 2 imaging microscope by Carl Zeiss were used. The sample preparation was carried out according to the State Pharmacopoeia of the Russian Federation (XIV edition). Anatomical diagnostic features were studied in powder and cross section with staining reagents for the presence of some biologically active substances. Qualitative reactions were carried out with water and alcohol-water extracts from the fruits. The content of the lipid complex according to pharmacopoeia monograph 2.5.0035.15 has been determined.Results. A description of the external and diagnostic anatomical features is given. The main groups of biologically active substances and the content of the lipid complex in a possible new material – the fruits of Nepeta cataria – have been identified.Conclusion. The description of the external features of the fruit has been specified. For the first time, crushed fruits have been characterized. It has been established that the morphology of endocarp cells and seed embryo cells are best preserved in a mellow fruit. Physico-optical properties of cellular structures and the ability for basic microchemical reactions are preserved in all zones of pericarp and seeds. Qualitative reactions showed the presence of the following components in the fruits: saponins, flavonoids and a lipid complex. A dispersion composition has been studied. The yield of the lipid complex and its appearance have been determined. Fruits can be used as promising fat-oil raw materials. The results of the study can be used in drafting Pharmacovigilance Reference Document considering a promising type of medicinal plant raw material on the basis of Nepetae catariae herba fruits.
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