Living liver donation from elderly donors for the patients with irresectable neuroendocrine liver malignancies can be as safe as deceased donation or liver donation from young donors (age < 50). Living donation from elderly donors might significantly expand the donor pool for patients with liver neuroendocrine tumors (NET) and potentially reduce waiting list mortality. Especially young patients with irresectable NET can benefit from this option. However, case-control studies are needed to verify the advantage of living liver transplantation (LDLT) for the patients with irresectable liver NET and to define selection criteria for these patients.
Method of finite element modeling was used for mathematic modeling of pelvic fractures and various variants of anterior and posterior pelvic ring fixation with reconstructive plates, cannu- lated sacroiliac screws and pelvic screws. Four most common types of fracture were simulated. Stress-deformed conditions of metal constructions for every type of fracture and variant of its fixation were determined. Study results enabled to determine the optimum fixation techniques in various types of fractures, to confirm the significance of both anterior and posterior pelvic stabilization, as well as to substantiate the possibility of early rehabilitation with full weight bearing in such severe patients
Method of finite element modeling was used for mathematic modeling of pelvic fractures and various variants of anterior and posterior pelvic ring fixation with reconstructive plates, cannu- lated sacroiliac screws and pelvic screws. Four most common types of fracture were simulated. Stress-deformed conditions of metal constructions for every type of fracture and variant of its fixation were determined. Study results enabled to determine the optimum fixation techniques in various types of fractures, to confirm the significance of both anterior and posterior pelvic stabilization, as well as to substantiate the possibility of early rehabilitation with full weight bearing in such severe patients
A bone defect of rectangular shape in a femur is considered as a result of a surgical resection of tumor lesions. Based on finite-element calculation of J-integral near the bone defect, ultimate combinations of loads corresponding to formation of microcracks were determined. The loads corresponds to simultaneous actions of own human's weight, flexion-extension, adduction-abduction and rotation of the femur. Recommendations for the prevention of pathological fractures of the femur with the surgical defect based on the obtained results were formulated.
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