Aim: The objective of this study was to assess whether an elderly patient’s frailty was associated with acute kidney injury (AKI) and to examine whether severe frailty group had an increased risk of AKI than mild–moderate group.Methods: We searched The Cochrane Library, PubMed, and EMBASE for relevant studies without language limitations before 1 March 2019 with a priori defined inclusion and exclusion criteria. Five population-based cohort studies were included for systematic review and meta-analysis.Results: Compared with the control group, the frailty group is significantly associated AKI (Odds Ratio = 2.05; 95% CI: 1.23–3.43). The moderate-severe frailty group has an increased risk of AKI than mild frailty group (Hazard Ratio = 2.87; 95% CI: 1.60–5.17.Conclusion: In conclusion, the available best evidence support an association between frailty and AKI among elder patients, thus relevant interventions should be taken among elderly under potential risk of AKI.
In recent years, online consumer credit in China has boomed. Many Chinese undergraduates are interested in utilizing online consumer credit to meet their increasing consumption needs. However, the explosion in online loans to students has created many problems. Based on a survey of 286 undergraduate students from four universities in Beijing, the capital of China, this study provides an empirical analysis of the economic and social determinants of undergraduates' consumer credit. The estimation results indicate that online consumer credit demand is positively related to years of schooling, monthly living expenses, financial support from the student's university, and consumption preferences. However, other factors, including major field of study, highest level of parental education, and advertisements in the media and on campus, have negative influences on undergraduates' online consumer credit. The findings have significant practical and policy implications. Specifically, it is necessary and important for the government, universities, and families to coordinate to guide and educate college students to utilize online loans properly and wisely.
Purpose: Many evidence-based studies have indicated that cinnamon has therapeutic effects. However, it may not be entirely safe and its adverse effects may be ignored. The present umbrella review was conducted to elucidate the safety of cinnamon.Methods: Pertinent meta-analyses and systematic reviews of randomized controlled trials on cinnamon use in humans were identified by searching PubMed, EMBASE, and the Cochrane Library from their inception to September 15, 2021. All meta-analyses and systematic reviews on the safety or adverse effects of cinnamon were considered. PRISMA 2020 was used as the standard of reporting (PRISMA registration ID: 286746).Results: We identified three meta-analyses and one systematic review that described the safety of cinnamon. The quality of the meta-analysis and systematic reviews was evaluated using “Assessing the Methodological Quality of Systematic Reviews.” Their quality was rated as low in two (50%) instances and moderate in two (50%). There were no significant toxic- or side effects between cinnamon group and placebo group regardless of dose and duration.Conclusion: There is evidence to support that the use of cinnamon has no adverse reactions. It can improve the health status of patients as an adjuvant treatment. Future studies exploring better profile risks and protective factors for cinnamon use-related adverse effect are needed, in order that preventive approaches can be developed.
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