Association of acute kidney injury with frailty in elderly population: a systematic review and meta-analysis

Jiesisibieke, Zhu Liduzi; Tung, Tao‐Hsin; Xu, Qin-Yi; Chen, Pei‐En; Hsu, Shih-Yung; Liu, Yongguang; Chien, Ching‐Wen

doi:10.1080/0886022x.2019.1679644

Cited by 30 publications

(33 citation statements)

References 32 publications

(43 reference statements)

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“…Huang, Fan, Ying, & Chen, 2019). As synonymous concepts of social participation can be used interchangeably, the search terms in this study were collected from previous systematic reviews or meta‐analyses to retrieve as many relevant resources as possible (Dalemans, de Witte, Lemmens, van den Heuvel, & Wade, 2008; Jiesisibieke et al, 2019; Shah, Frank, & Ehrlich, 2020). To further guarantee our reasonable selection of these terms and their relevant meanings, our team discussed them and invited suggestions from experienced specialists in the field of geriatric care and information specialists.…”

Section: Methodsmentioning

confidence: 99%

Global scientific research on social participation of older people from 2000 to 2019: A bibliometric analysis

Jiang

Hong

et al. 2020

Int J Older People Nursing

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BackgroundSocial participation is an indicator of successful ageing and important determinant of health outcomes. As more studies have been conducted on social participation of older people, a comprehensive and quantitative analysis of the current literature will contribute to a better understanding of the main and novel issues and improve existing geriatric care services in this domain. However, limited bibliometric analysis was employed in this research field. Therefore, we conducted this study to investigate the research trend and quantitatively and comprehensively characterise the landscapes of publications on social participation of older people via bibliometric analysis methods.MethodsData were obtained from the Web of Science Core Collection in January 2020. CiteSpace 5.5.R2 and VOSviewer software packages were used to generate knowledge maps and analyse the publication outputs, countries/regions, institutions, journals, research hot spots and research frontiers.ResultsA total of 7,029 publications between 2000 and 2019 were retrieved, and the publication number per year continues to increase. The United States held a leading position in this research field, and Duke University was the most productive institution. Co‐cited reference cluster analysis and keyword co‐occurrence analysis showed that research hot spots contained factors of healthy ageing, quality of life, psychological problems and health status, especially dementia, function (including cognitive function) and frailty. Burst detection of keywords revealed that social participation, social support, instrumental activity, frailty and loneliness have been new research frontiers since 2015.ConclusionsBy analysing publications over the past 20 years, we found publication trends and characteristics in this field. These findings will hopefully provide new insight into the scientific landscapes and further directions in the study of social participation of older people.Implications for PracticeSocial participation is strongly associated with physical and psychological problems and the well‐being of older people. Related professionals, such as social workers, psychologists, nurses and many other health care practitioners, should raise widespread awareness and concern over research hot spots and frontiers on this topic to promote research knowledge translation and adoption into the practice of caring for older people.

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Section: Methodsmentioning

confidence: 99%

Global scientific research on social participation of older people from 2000 to 2019: A bibliometric analysis

Jiang

Hong

et al. 2020

Int J Older People Nursing

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“…Usually the term ‘‘elderly’’ denotes broadly older individuals, but there is not universally accepted definition or cut-off age. Indeed, many authors have proposed various ages ranging from 60 years (indicated as elderly) to >80 years (indicated as very elderly) in the attempt to define the aged status [ 15 , 16 , 17 ]. Currently, it is reasonable to call “elderly” a patient with age >65 years.…”

Section: Introductionmentioning

confidence: 99%

Molecular Mechanisms of AKI in the Elderly: From Animal Models to Therapeutic Intervention

Infante

Franzin

Madio

et al. 2020

JCM

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Acute kidney injury (AKI), a critical syndrome characterized by a sudden reduction of renal function, is a common disorder among elderly patients particularly in Intensive Care Unit (ICU). AKI is closely associated with both short- and long-term mortality and length of hospital stay and is considered a predictor of chronic kidney disease (CKD). Specific hemodynamic, metabolic, and molecular changes lead to increased susceptibility to injury in the aged kidney; therefore, certain causes of AKI such as the prerenal reduction in renal perfusion or vascular obstructive conditions are more common in the elderly; moreover, AKI is often multifactorial and iatrogenic. Older patients present several comorbidities (diabetes, hypertension, heart failure) and are exposed to multiple medical interventions such as the use of nephrotoxic contrasts media and medications, which can also trigger AKI. Considering the emerging relevance of this condition, prevention and treatment of AKI in the elderly should be crucial in the internist and emergency setting. This review article summarizes the incidence, the risk factors, the pathophysiology, the molecular mechanisms and the strategies of prevention and treatment of AKI in elderly patients.

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“…In other words, to mitigate the AKI risk level of an elderly patient, adequate enhancement of daily activities and nutrition might offer another type of treatment; those two criteria would improve an elderly patient's overall frailty. This finding is complementary to the result of [15]. Under certain controllable circumstances, elderly patients may improve their frailty before surgery that might cause AKI complications.…”

Section: Dematel-based Anp (Danp) Weightsmentioning

confidence: 64%

Clinical Knowledge Supported Acute Kidney Injury (AKI) Risk Assessment Model for Elderly Patients

Shen

Chuang

Tung

2021

IJERPH

Self Cite

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From the clinical viewpoint, the statistical approach is still the cornerstone for exploring many diseases. This study was conducted to explore the risk factors related to acute kidney injury (AKI) for elderly patients using the multiple criteria decision-making (MCDM) approach. Ten nephrologists from a teaching hospital in Taipei took part in forming the AKI risk assessment model. The key findings are: (1) Comorbidity and Laboratory Values would influence Comprehensive Geriatric Assessment; (2) Frailty is the highest influential AKI risk factor for elderly patients; and (3) Elderly patients could enhance their daily activities and nutrition to improve frailty and lower AKI risk. Furthermore, we illustrate how to apply MCDM methods to retrieve clinical experience from seasoned doctors, which may serve as a knowledge-based system to support clinical prognoses. In conclusion, this study has shed light on integrating multiple research approaches to assist medical decision-making in clinical practice.

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Association of acute kidney injury with frailty in elderly population: a systematic review and meta-analysis

Cited by 30 publications

References 32 publications

Global scientific research on social participation of older people from 2000 to 2019: A bibliometric analysis

Global scientific research on social participation of older people from 2000 to 2019: A bibliometric analysis

Molecular Mechanisms of AKI in the Elderly: From Animal Models to Therapeutic Intervention

Clinical Knowledge Supported Acute Kidney Injury (AKI) Risk Assessment Model for Elderly Patients

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