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In order to improve the forming quality of the Inconel 625 cladding layer and make it to be more widely used. This paper addresses an experimental investigation on the influence of major process parameters like laser power, scanning speed, powder feed rate, and overlapping rate along with their interactions on surface roughness and width error of laser additive manufacturing process for forming Inconel 625 samples. Taguchi method and grey relational analysis were used to optimize the selected parameters, and the verification tests were carried out. The change of microhardness and microstructure in the overlapping zone and nonoverlapping zone of the cladding layer were studied by microhardness tester and scanning electron microscopy (SEM). The results show that the most significant effect in processing parameters on surface roughness and width error are both overlapping rate, and the optimal levels of laser power, scanning speed, powder feeder rate, and overlapping rate are 1800 W, 8 mm/s, 10 g/min, and 30%, respectively. Analysis of microstructure and composition showed that the content of Cr was high both in the Laves phase and matrix, the content of Nb in the Laves phase increased significantly and reached up to 24.48 wt%, and the Laves in the nonoverlapping zone was more compact than the overlapping zone.

Customized generation of 3D functional building blocks is crucial for bottom‐up tissue engineering. Currently, high throughput production, high survival rates, and well‐controlled shapes are considered as three major challenges in fabricating microgels. Here, an optofluidic maskless lithography system that combines digital micromirror device based 3D printing and microfluidic technologies for fabricating 3D functional microgels, is presented. With this system, 3D microgels can be custom designed online and manufactured modularly in a microfluidic device. The fabrication process is based on shadowed light, highly flexible, and requires no physical masks. Furthermore, cells in microgels exhibit features that are more similar to the complex in vivo conditions, including morphology, proliferation, and drug resistance.

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The distribution law of residual stress in multi-channel scanned plasma cladding of Co-based alloy under different process parameters was studied by means of simulation and tests, and the optimum process parameters were optimized. The simulation model of the plasma cladding stress field was established by ABAQUS software, and the influence law of the working current, scanning speed, and scanning mode on the residual stress of the Co-based alloy multi-channel scanning was studied. A set of optimal cladding process parameters were obtained. The residual stress of the cladding layer was measured by the blind hole method and compared with the stress value in the finite element model. The results show that there is residual tensile stress on the surface of the cladding layer. The residual stress along the direction of the scanning path is greater than that along the direction of the scan sequence. The residual stress increases with the increase of the working current. The scanning speed is greater, and the residual stress is smaller. The residual stress of the short-edge scanning is greater than that of the long-edge scanning. The residual stress of the successive scanning is greater than that of the reciprocating scanning. The long-edge reciprocating scanning is the best scanning mode. The best combination of process parameters is the working current of 90 A, the scanning speed of 100 mm/min, and the long-edge reciprocating scanning mode.