The oxygen exchange kinetics of thin films of the oxygen-deficient double perovskite PrBaCo2O5+δ (PBCO) have been determined by electrical conductivity relaxation (ECR) and by oxygen-isotope exchange and depth profiling (IEDP). Microstructural studies indicate that the PBCO films, prepared by pulsed laser deposition, have excellent single-crystal quality and epitaxial nature. The ECR and IEDP measurements reveal that the PBCO films have high electronic conductivity and rapid surface exchange kinetics, although the ECR data indicate the presence of two distinct kinetic pathways. The rapid surface kinetics compared with those of other perovskites suggest the application of PBCO as a cathode material in intermediate-temperature solid oxide fuel cells.
Routine follow-up visits and radiographic imaging are required for outcome evaluation and
tumor recurrence monitoring. Yet more personalized surveillance is required in order to
sufficiently address the nature of heterogeneity in nonsmall cell lung cancer and possible
recurrences upon completion of treatment. Radiomics, an emerging noninvasive technology
using medical imaging analysis and data mining methodology, has been adopted to the area
of cancer diagnostics in recent years. Its potential application in response assessment
for cancer treatment has also drawn considerable attention. Radiomics seeks to extract a
large amount of valuable information from patients’ medical images (both pretreatment and
follow-up images) and quantitatively correlate image features with diagnostic and
therapeutic outcomes. Radiomics relies on computers to identify and analyze vast amounts
of quantitative image features that were previously overlooked, unmanageable, or failed to
be identified (and recorded) by human eyes. The research area has been focusing on the
predictive accuracy of pretreatment features for outcome and response and the early
discovery of signs of tumor response, recurrence, distant metastasis, radiation-induced
lung injury, death, and other outcomes, respectively. This review summarized the
application of radiomics in response assessments in radiotherapy and chemotherapy for
non-small cell lung cancer, including image acquisition/reconstruction, region of interest
definition/segmentation, feature extraction, and feature selection and classification. The
literature search for references of this article includes PubMed peer-reviewed
publications over the last 10 years on the topics of radiomics, textural features,
radiotherapy, chemotherapy, lung cancer, and response assessment. Summary tables of
radiomics in response assessment and treatment outcome prediction in radiation oncology
have been developed based on the comprehensive review of the literature.
Ferroelectric Ba0.6Sr0.4TiO3 thin films with 2% Mn additional doping were grown on (001) MgO by pulsed laser deposition. The microstructural studies from x-ray diffraction and transmission electron microscopy indicate that the films are highly epitaxial with c-axis oriented and atomic sharp interface. Dielectric property measurements at 1 MHz and room temperature reveal that the as-grown films have outstanding dielectric properties with large tunability of 80% at 40KV∕cm, very large dielectric constant value of 3800, and extra low dielectric loss of only 0.001. The high frequency (10–30 GHz) dielectric measurements demonstrate that the films are excellent in both dielectric property and very low dielectric insertion loss. Compared with the pure BSTO films or traditional doping, the additional doping of Mn in BSTO thin films can significantly improve the dielectric property of the as-grown films.
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