Neonatal seizures are the most common neurological emergency in the neonatal period and are associated with a poor long-term outcome. Early detection and treatment may improve prognosis. This paper aims to develop an optimal set of parameters and a comprehensive scheme for patient-independent multichannel EEG-based neonatal seizure detection. We employed a dataset containing 411 neonatal seizures. The dataset consists of multi-channel EEG recordings with a mean duration of 14.8 h from 17 neonatal patients. Early-integration and late-integration classifier architectures were considered for the combination of information across EEG channels. Three classifier models based on linear discriminants, quadratic discriminants and regularized discriminants were employed. Furthermore, the effect of electrode montage was considered. The best performing seizure detection system was found to be an early integration configuration employing a regularized discriminant classifier model. A referential EEG montage was found to outperform the more standard bipolar electrode montage for automated neonatal seizure detection. A cross-fold validation estimate of the classifier performance for the best performing system yielded 81.03% of seizures correctly detected with a false detection rate of 3.82%. With post-processing, the false detection rate was reduced to 1.30% with 59.49% of seizures correctly detected. These results represent a comprehensive illustration that robust reliable patient-independent neonatal seizure detection is possible using multi-channel EEG.
In order to realize the Johnson U BV and Kron-Cousins RI photometric systems in BFOSC, glass filters were purchased according to the Bessell prescription. All the filters are anti-reflection coated on both sides to increase the transmission. By comparing two dome flat-field exposures taken through any one of these filters set in two orientations 90 • apart, inhomogeneities in the filter transmission is clearly demonstrated. Using a PDS microphotometer, we have confirmed that the form of their spectral transmission curve varied from point to point on the filters. This kind of inhomogeneity cannot be eliminated by dividing by flat-fielding exposure and must be ascribed to inhomogeneities in the coating. This is not some accidental defect in coating, it is in the existing coating technique because all the filters (including the narrow-band interference ones) for the BFOSC and a Hβ filter made by another manufacturer showed a similar pattern. We found that for the studies of variable stars with amplitudes less than 0.05 mag. or studies aiming at establishing accurate C-M diagrams of star clusters, the usual uncoated Schott glass filters of Bessell's prescription are to be preferred.
Intending to use semiconductor films for piezoresistive elements, polycrystalline silicon films are prepared by electron bombardment method on insulating substrates and electrical properties of the films are investigated. Gage factor of the film is in the vicinity of 25, temperature coefficient of resistance and gage factor is about 1.8×10-4/°C, 1.1×10-3, respectively, for the resistivity of an order of 10-3 Ω cm. Much smaller coefficients are obtained by heat treament.
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