This study examines the influence of economic and political factors that contribute to the convergence and/or divergence in value priorities of five East Asian societies—China, Hong Kong, Singapore, South Korea, and Taiwan. We find that political and social-economic factors influence the values orientations of managers within this region. However, economic development level is an insufficient explanation for values convergence without consideration of the societal context and cultural traditions in which that development occurred. Copyright Springer Science+Business Media, LLC 2007Cross-cultural values, Asian tigers, China,
Gastric cancer (GC) is one of the most common types of malignancy worldwide, with high morbidity and mortality rates. The dysregulation of microRNAs (miRs) has been found to be involved in the carcinogenesis of GC. The present study aimed to investigate the underlying association between GC and miR-320a. Analysis using reverse transcription quantitative polymerase chain reaction indicated that the expression of miR-320a was downregulated and the expression of RAB14 was upregulated in GC tissues and cells, compared with the corresponding controls. MTT, colony formation assays, and flow cytometric analyses were used to evaluate the effect of miR-320a on cell proliferation and the cell cycle. The ectopic expression of miR-320a using miR-320a mimics suppressed cell viability, inhibited G1/S transition, and induced apoptosis in AGS and MKN45 cells. In addition, RAB14 was identified as a direct target gene of miR-320a, according to the results of bioinformatics analysis and a luciferase reporter assay. Downregulation of RAB14 by RAB14-small interfering RNA inhibited the viability of GC cells, which was similar to the phenotype of miR-320a mimics. Furthermore, the reintroduction of RAB14 partially abrogated the miR-320a-mediated downregulation of RAB14 and rescued the miR-320a-induced effects on GC cell growth. These findings suggest a potential novel therapeutic target for the treatment of GC.
China has been suffering from air quality degradation since its ascension into the World Trade Organization in 2001. The unequal exchange that occurs with international trade—that is, developed countries obtaining larger shares of trade‐related value added relative to the shares of trade‐related air pollution incurred locally—may obstruct the greening of global supply chains. In this study, we conduct a multi‐regional input‐output analysis to examine the change in the distribution of economic benefits and sulfur dioxide emissions underlying China's international trade from 2002 to 2015. The results show that both net trade‐related economic benefits and SO2 emissions in China rapidly increased from 2002 to 2007 and then decelerated after 2007 due to changes in China's green development strategy. In the past 13 years, China has suffered from economic‐environmental inequality due to trade with most developed countries, for example, the United States, the European Union, East Asia, and Canada. East Asia, particularly Japan and South Korea, became both an economic and environmental winner while trading with China in 2015. China has also outsourced emissions to less developed regions, such as Sub‐Saharan Africa. We propose policy implications to further reduce the economic‐environmental inequality underlying China's international trade.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.