We studied the distribution, seasonal change, translocation, and source of heavy metal Pb based on the surface and bottom water sampling in Jiaozhou Bay in 1980 in order to know the condition of Pb before the industrial and agricultural development and to probe the distribution and translocation process of Pb. The results show that the range of Pb content in the surface in the whole bay was 0.07-2.71 μg/L, being below Grade Ⅱ of the China’s national water quality benchmark (5.00 μg/L). No Pb pollution was detected in the inner bay, while in the outer bay and the mouth, light Pb pollution. The Pb pollution in the bay waters was area sources. Horizontal and vertical distribution, and seasonal change indicated the translocation of Pb in the waters. Pb entered the water body at marine surface and sank at the marine bottom. Understanding the variable process of Pb in the bay provided the scientific clues for controlling Pb pollution from the human activities

Wood pulp/Danufil nonwovens have been prepared by wetlaid/spunlace method as a potential and new dispersible moist wipes. To verify the potential applications of the wetlaid/spunlace nonwovens, this study investigated the wet strength, softness/smoothness, and dispersibility of wetlaid/spunlace nonwovens with different Danufil contents and length-to-diameter ratios. Meanwhile, these properties were compared with three other types of commonly-used dispersible moist wipes. The results show that an increase in Danufil content or length-to-diameter ratio results in increasing wet strength and decreasing dispersibility of wetlaid/spunlace nonwovens. However, an increase in pulp content or Danufil length-to-diameter ratio will increase real softness and weaken felt smoothness of materials. In addition, the average machine and cross directions wet strength are 9.5 N/50 mm and 6.3 N/50 mm, respectively. The real softness and corresponding felt smoothness of wetlaid/spunlace nonwovens range from 10.8 to 16.3 and from 37.1 to 22.0, respectively. The average required dispersion time of wetlaid/spunlace nonwovens are controlled within 21 min. Overall, the wood pulp/Danufil wetlaid/spunlace nonwovens have the similar wet strength but excellent softness/smoothness and dispersibility when compared with the currently used dispersible products, and possess high feasibility and potential for dispersible moist wipes industry.

The demand for air filtration materials in recent years has been substantially increasing on a worldwide scale because people are paying extensive attention to particulate matter (PM) pollution. In this work, we report a type of needle-punched triboelectric air filter (N-TAF) consisting of polytetrafluoroethylene (PTFE) fibers modified by silica nanoparticles and polyphenylene sulfide (PPS) fibers. Compared to conventional electrostatic precipitators, the N-TAF can be charged online by a unique nonwoven processing technology without additional energy consumption and toxic ozone emission. Owing to the triboelectrification effect, a large number of charges were generated during the process of carding and needle-punching, resulting in an increased filtration performance. Benefiting from the addition of silica nanoparticles, the PTFE fibers are endowed with many pores and grooves and substantial surface roughness, which contributes to the enhancement of triboelectrification. As a result, the N-TAF with 2 wt % silica nanoparticles (N-TAF-2) exhibited a high removal efficiency of 89.4% for PM, which is 45% higher than unmodified N-TAF (61.8%), and a low pressure drop of 18.6 Pa. Meanwhile, the decay of the removal efficiency for N-TAF-2 remained at a low level (6.4%) for 60 days. More importantly, N-TAF-2 could realize a high efficiency of 99.7% and a low pressure drop of 55.4 Pa at a high surface density. In addition, the washed N-TAF has an excellent charge regeneration performance via air blowing or manual rubbing, thus recovering the removal efficiency easily and rapidly. Ultimately, the powerful dust holding capacity (227 g m–2) for N-TAF-2 indicates that the filter has a long service life, which makes it a promising air purification material. The filter reported in this work has the potential to be practically applied to air purification fields because it has excellent filtration performance and is easy to be produced on a large industrial scale.

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Immunosuppressive tumor microenvironment in hepatocellular carcinoma (HCC) is critical in tumor development. C-type (Ca2+ -dependent) lectin (CLEC) receptors, essential in innate pattern recognition, have potential regulatory effects on immune cell trafficking and modulatory effects on cancer cell activity. However, information on the expression and prognostic value of CLECs in HCC is scanty. Herein, we explored the potential role of CLECs in HCC based on TCGA, ONCOMINE, GEPIA, UALCAN, cBioPortal, Metascape, TRRUST, and TIMER databases. Results demonstrated a significantly higher mRNA level of CLEC4A and CLEC4L in HCC tissues than normal liver tissues. Contrarily, we found significantly low CLEC4G/H1/H2/M expression in HCC tissues. The IHC analysis revealed the following: Absence of CLEC4A/J/K/M in normal and liver cancer tissues; high CLEC4C expression in HCC tissues; low expression and zero detection of CLEC4D/E/H1/H2/L in HCC tissues and normal tissues, respectively. And the HepG2 and LX-2 were used to verify the expression level of CLEC4s via qRT-PCR in vitro. Furthermore, the expression of CLEC4H1 (ASGR1) and CLEC4H2 (ASGR2) exhibited a significant relation to clinical stages. However, the expression of CLEC4A, CLEC4D, CLEC4E, CLEC4J (FCER2), CLEC4K (CD207), CLEC4G, CLEC4H1, CLEC4M, and CLEC4H2 decreased with tumor progression. Patients expressing higher CLEC4H1/H2 levels had longer overall survival than patients exhibiting lower expression. Moreover, CLEC4A/D/E/J/K/G/H1/M/H2 had significant down-regulated levels of promoter methylation. The expression level of CLEC4s was correlated with the infiltration of B cells, CD8 + T cells, CD4 + T cells, macrophage cells, neutrophil cells, and dendritic cells. Functional analysis revealed the potential role of CLECL4s in virus infection, including COVID-19. Also, hsa-miR-4278 and hsa-miR-324-5p, two potential miRNA targets of CLEC4s, were uncovered. This article demonstrates that CLEC4 is crucial for the development of HCC and is associated with infiltration of various immune cells, providing evidence for new immunotherapy targets in HCC.

Developing wet-laid papers with a good wet strength remains a longstanding challenge in the papermaking industry. In this study, hydroentanglement, a mechanical bonding technique is developed to consolidate the wet-laid fibre web. The results indicate that wet tensile strength, ductile stretching property, softness, air permeability and water absorbency of the wet-laid fibre web are significantly improved by hydroentanglement. In addition, the abrasion test shows that the dusting off rate of wet-laid fibre web can be effectively reduced through hydroentanglement. Moreover, the disintegration experiment proves that wet-laid hydroentangled nonwovens could be easily dispersed when compared with conventional carded hydroentangled nonwovens. Therefore, the new wet-laid hydroentangled nonwovens can maintain excellent performance in a wet state, showing a great potential for personal hygiene applications.

Wetlaid/spunlace(wetlace) nonwovens with sufficient wet strength in use and disintegration under flow field can be widely used in dispersible moist wipes. To achieve superior properties, wood pulp/Lyocell wetlace nonwovens at different process parameters including pressure sum (sum of each Jet Head pressure), Lyocell blend ratio, and basis weight were prepared. Meanwhile, the effects of these process parameters on the wet strength and dispersibility of materials were investigated. The results show that the wet strength of wood pulp/Lyocell wetlace nonwoven increases as the increase of process parameters. Pressure sum has positive linear relationship with material wet strength and exponential relationship with material dispersibility. When pressure sum is beyond 135 bars, material basis weight has significant influence on the dispersibility. Pressure sum of 210 bars is the key value that Lyocell content affects the material dispersibility. Overall, at the minimum pressure sum of 190 bars, wood pulp/Lyocell (60/40) wetlace nonwoven (80 g m −2 ) has dispersion critical value with maximum wet strength.