Sn-Beta zeolites, with high Sn content and smaller crystal size, hydrothermally synthesized in F−-free medium using N-cyclohexyl-N,N-dimethylcyclohexanaminium hydroxide as the structure-directing agent with the assistance of Na+ and seed, are highly active as Lewis acid catalysts.
Early infection and peri‐implantitis after implant restoration are major reasons for dental implant failure. Implant‐associated infections are majorly attributed to biofilm formation. In this study, co‐incorporated zinc‐ (Zn‐) and strontium‐ (Sr‐) nanorod coating on sandblasted and acid‐etched (SLA) titanium (SLA‐Zn/Sr) was fabricated by hydrothermal synthesis. It was aimed at promoting osteogenesis while inhibiting biofilm formation. The nanorod‐like particles (φ 30–50 nm) were found to be evenly formed on SLA‐Zn/Sr (Zn: 1.49 ± 0.16 wt%; Sr: 21.69 ± 2.74 wt%) that was composed of well‐crystallized ZnTiO3 and SrTiO3 phases. With a sufficient interface bonding strength (42.00 ± 3.00 MPa), SLA‐Zn/Sr enhanced the corrosion resistance property of titanium. Besides, SLA‐Zn/Sr promoted the cellular initial adhesion, proliferation and osteogenic differentiation of rBMSCs in vitro while inhibiting the adhesion of Staphylococcus aureus and Porphyromonas gingivalis . In addition, through down‐regulating icaA gene expression, this novel surface reduced the secretion of polysaccharide intercellular adhesion (reduced by 87.9% compared to SLActive) to suppress the S. aureus biofilm formation. We, therefore, propose a new chemical modification on titanium for multifunctional implant material development. Due to the Zn/Sr co‐doping in coating, material properties, early osteogenic effect and antibacterial ability of titanium can be simultaneously enhanced, which has the potential to be applied in dental implantation in the future.
Objective
To evaluate the long‐term integrity of implant–abutment complexes in implant systems with two internal conical angles.
Material and Methods
12,538 bone‐level implants of two systems placed between January 2012 and December 2018 were retrospectively analyzed. Cumulative abutment/implant fracture rates in systems with larger (LA, 7.5°) and smaller (SA, 5.7°) internal conical angles were estimated using the Kaplan–Meier analysis and compared between groups. The association between implant systems and jammed abutment retrievability was evaluated by multivariable generalized estimating equation logistic regression modeling.
Results
For LA, the 8‐year cumulative incident rate was 0.10% (95% confidence interval (CI): 0–0.24%) for implant fracture and 0.26% (95% CI: 0.11%–0.41%) for abutment fracture, demonstrating a significant difference in gender (p = .03), implant diameter (p = .01), jaw (p = .006), and antagonist tooth (p < .001). For SA, the 8‐year cumulative incident rate was 0.38% (95% CI: 0–0.79%) for implant fracture and 2.62% (95% CI: 0.05%–5.13%) for abutment fracture, which was influenced by implant diameter (p < .001) and site (p = .03). The cumulative implant/abutment fracture rate was lower for LA implants, particularly for LA implant‐supported single crowns (SCs) (p < .05). The abutment‐retrieval success rate was 92.9% for LA and 57.1% for SA (p = .055).
Conclusion
LA implants exhibited a lower incidence of fracture in abutment–implant complexes and a relatively higher retrievability success rate for jammed abutments.
Background : A series of biological events was initiated upon the implantation placement, beginning with blood-material contact, followed by coagulation cascade, blood clot formation and bone marrow mesenchymal stromal cells (BMSCs) recruitment. Aim/Hypothesis : The aim of this study was to investigate the effect of implant surface on blood-material interactions and subsequent rBMSCs cellular behaviors via mimicking physiological process in vitro and in vivo. Materials and Methods : This study established in vivo and in vitro to imitate the physiological process of implantation. Titanium slices with sandblasted and double acid-etching (SLA) surface, while polished titanium (PT) surfaces as control group, were incubated with whole blood for 10 min or 2 h, then rBMSCs were seeded. The adhesion, proliferation, migration and differentiation of rBMSCs were studied at specific time points. Titanium implants with different surfaces were implanted into the tibia of Sprague-Dawley (SD) rats and were screwed out at 10 min or 2 h after implantation. The activation of coagulation cascade, platelets and complement system and the clot networks were observed and further quantitatively analyzed. Results : Compared with PT surface, the SLA surface induced the greater and earlier surface-induced blood coagulation cascade and showed more stratified clots network with adsorption of fibrinogen, platelets and CD14 positive cell. Furthermore, increased rBMSCs proliferation as well as the migration and movement of cells were induced by titanium surface pre-incubated with whole blood. Finally, the higher expression levels of the osteogenic-related and angiogenic-related genes showed on SLA surfaces with blood incubation. Conclusions and Clinical Implications : SLA titanium surfaces positively influenced the formed clot structure with entrapped blood components, blood-surface interactions and subsequent cellular biological processes which are important for early bone healing and integration.
Background : The bone level implant systems have gained general acceptance in edentulous restorations. Despite of the satisfactory clinical performance, the implant component fracture is occurring. It is a challenging and laborious complication for dentists to tackle with. From the patients' point of view, it is also time-consuming and effort-consuming. Aim/Hypothesis : The aim of this study is to post clinical suggestion for the management of implant component fracture and to provide technical advice for implant design through a series of implant component fracture took place in 2 bone level implant systems over a function period varying from 1 year to 8 years.
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