Paper-based transparent flexible thin film supercapacitors were fabricated using CNF-[RGO]n hybrid paper as an electrode material and charge collector. Owing to the self-anti-stacking of distorted RGO nanosheets and internal electrolyte nanoscale-reservoirs, the device exhibited good electrochemical performance (about 1.73 mF cm(-2)), and a transmittance of about 56% (at 550 nm).
Oil spill accidents have seriously harmed the marine environment. Effective oil spill monitoring can provide strong scientific and technological support for emergency response of law enforcement departments. Shipborne radar can be used to monitor oil spills immediately after the accident. In this paper, the original shipborne radar image collected by the teaching-practice ship Yukun of Dalian Maritime University during the oil spill accident of Dalian on 16 July 2010 was taken as the research data, and an oil spill detection method was proposed by using LBP texture feature and K-means algorithm. First, Laplacian operator, Otsu algorithm, and mean filter were used to suppress the co-frequency interference noises and high brightness pixels. Then the gray intensity correction matrix was used to reduce image nonuniformity. Next, using LBP texture feature and K-means clustering algorithm, the effective oil spill regions were extracted. Finally, the adaptive threshold was applied to identify the oil films. This method can automatically detect oil spills in shipborne radar image. It can provide a guarantee for real-time monitoring of oil spill accidents.
Context
Metabolic associated fatty liver disease (MAFLD) is the hepatic manifestation of obesity-related metabolic syndrome (MetS). Non-invasive biomarkers for monitoring the progression and severity of these metabolic comorbidities are needed.
Objectives
To investigate the associations of serum thrombospondin-2 (TSP2) with MetS and MAFLD severity, and the potential diagnostic value of serum TSP2 for identifying at-risk metabolic associated steatohepatitis (at-risk MASH).
Methods
Blood samples, clinical data, and liver biopsies were collected from consecutively recruited 252 individuals with morbid obesity receiving bariatric surgery. Histopathology of liver biopsies were examined in a blinded fashion by three independent pathologists. Serum TSP2 levels were measured by ELISA.
Results
Serum TSP2 levels were significantly elevated in MetS (1.58 (1.07-2.20) ng/mL) compared with non-MetS (1.28 (0.84-1.73) ng/mL; P=0.006) in obese patients and positively correlated with increasing number of the MetS components, fasting glucose, HbA1c, fasting insulin, C-peptide, HOMA-IR after adjustment of conventional confounders. Serum TSP2 levels differentiated MASH (1.74 (1.32-3.09) ng/mL) from the other non-MASH less severe groups normal liver (1.41 (1.04-1.63) ng/mL), simple steatosis (1.45 (0.89-1.92) ng/mL) and borderline MASH (1.30 (0.99-2.17) ng/mL) (P<0.05). Elevated serum TSP2 was positively associated with the severity of hepatic steatosis, inflammation, fibrosis, and abnormal liver function independent of age, sex and adiposity. Furthermore, high serum TSP2 identified at-risk MASH with AUC of 0.84 (95%CI 0.70-0.98).
Conclusions
Serum TSP2 is closely associated with severity and progression of MetS and MAFLD, and is a promising noninvasive biomarker for differentiating MASH from benign steatosis and identifying at-risk MASH patients among individuals with obesity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.