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Background Bariatric and metabolic surgery (BMS) is an effective treatment for obesity and its complications, but its effect on pregnancy outcomes is inconclusive. The present study aimed to investigate women’s pregnancy status and outcomes as well as the impact of pregnancy intervals after BMS. Methods The menstrual cycle and fertility status of women who underwent BMS in our centre between July 2010 and January 2021 were retrospectively analyzed and followed up until one-year post-delivery. The pregnancy outcomes after BMS were observed, including changes in weight, pregnancy interval, pregnancy complications, weight and health status of the newborn (premature birth, admission to neonatology, or deformity). Results We identified 31 women who were successfully conceived after BMS. There were statistical differences in weight and menstrual status before and post-operation ( P < 0.05), and 77.97% of them had remission or recovery of obesity-related comorbidities. Eighteen patients delivered successfully after BMS, but there were still 12 cases of spontaneous abortion and 1 case of induced abortion. The abortion rate in pregnancy intervals less than 2 years was higher than those ≥2 years ( P = 0.045). Of the women who delivered successfully, 5 had pregnancy-specific complications, including gestational diabetes mellitus and hypertensive disorder of pregnancy. However, the growth and development of the newborn are normal since the birth follow-up. Conclusion The present results suggest that the abortion rate in pregnancy intervals less than 2 years was higher than those ≥2 years. It is recommended that postoperative patients avoid pregnancy until their weight is stable to reduce the risk of adverse pregnancy outcomes.

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Escape routing has become a critical issue in high-speed PCB routing. Most of previous work paid attention to either differential-pair escape routing or single-signal escape routing but few considered them together. In this paper, a unified ILP model is used to formulate the problem of escape routing of differential pairs together with single signals (mixed-pattern signals) on staggered pin array. A mixedpattern escape routing algorithm is proposed to solve the problem and a slice-based heuristic method is presented to speed up the algorithm. Experimental results show that the proposed method is very efficient. It can solve all the test cases in short time and improve wire length and chip area by 13.8% and 13.4% respectively compared to traditional pin array. At the same time, the method can increase routability by 16.3% and reduce the wire length by 9.3% compared to a two-stage method.

Postprandial hyperinsulinemic hypoglycemia (PHH) is one of the serious complications after bariatric surgery, it can lead life-threatening neuroglycopenic symptoms, such as seizures, disorientation, impairment of version and loss of consciousness without any premonitory. The presentation, prevalence, diagnosis, pathology and treatment are reviewed in this summary.