Background: Dayak Onion (Eleutherine bulbosa Urb.) is a typical plant of Kalimantan which is traditionally used by the Dayak community as a medicinal plant. Dayak onion bulbs have been proven had many pharmacology activities. Objective: This study aims to determine the nonspesific and specific parameters of 70% ethanol extract of Eleutherine bulbosa Urb. Total flavonoids was also quantified Methods:. Eleutherine bulbosa Urb was extracted with maseration method used etanol 70 % as solvent. Determination of non-spesific includes by determined specific gravity, water content, total ash content, acid insoluble ash content, residual sovents, heavy metanol contamination, microbial contamination, mold and yeast contamination. Determination of specific parameters included extract identity, organoleptic extract, water/ethanol soluble content, chromatography profile. Total flavonoid content were quantified with colorimetric method. Results: there were no significance difference between nonspesific and specific parameters Eleutherine bulbosa Urb from three different locations. Measurement of total phenol content and total flavonoid content respectively form South Borneo were ; 6,499 ± 0,5248 mg QE/g extract, from central borneo were 7,585 ± 0,0437 mgQE/g extract, and from east borneo were 5,035 mg ± 0,3887 mgQE/g extract. Conclusion: it can be concluded that bulbs of Eleutherine bulbosa Urb from three locations have characters to similar between each other and bulbs of Eleutherine bulbosa Urb form central borneo had the highest total flavonoid content.
Rosella (Hibiscus sabdariffa L.) and telang flower (Clitoria ternatea L.) contain anthocyanins which have antioxidant, so the researchers combined to use as effervescent granules. This study aims to determine the characteristics, and the antioxidant activity of effervescent granule combination of rosella and telang flower extract. Antioxidant activity testing using DPPH. The antioxidant activity of the combined thick extract was obtained 𝐼𝐶 50 7.5 ppm, after that it was made into an effervescent granule preparation in 4 formulas. The resut show that all formulas had a characteristic taste of almost uniform color, dark turquoise. In all test formulas for water content, the results obtained are 1.68%-2.82%, compressibility index 11.641%-16%, angle of repose 31.2º-34.43º, flow time 6.25-6.83 seconds, dissolving time 208 -257 seconds and pH 6.2-6.6. The results of the antioxidant activity of effervescent granules revealed 𝐼𝐶 50 of 62,628 ppm (strong).
Objective: This study aims to compare the anti-Propionibacterium acnes activity between the optimum formula of gel liquid crystal nanoparticles of Binjai leaves methanol extract and the gel of extract without the liquid crystal nanoparticles system.
Methods: Preparation of liquid crystal nanoparticles using top-down methods with 6% Capmul-GMO 90 and 5% Plantacare 818. Preparation of the optimum gel formula using 7% Viscolam Mac 10 as a gelling agent. The antibacterial activity was evaluated by cup plate technique and clindamycin was used as a positive control.
Results: The results obtained are liquid crystal nanoparticles based gel of methanol extract of Binjai leaves produces a strong category as anti-Propionibacterium acnes with an average inhibition of 15.33±1.2413 mm and the gel of extract without the liquid crystal nanoparticles system only produces 13.53±1.241 mm.
Conclusion: The gel of Binjai leaves extract with a liquid crystal nanoparticles system has a higher antibacterial effect on Propionibacterium acnes than the gel of extract without the liquid crystal nanoparticles system.
Salah satu tanaman dari Kalimantan yaitu bawang dayak (Eleutherine bulbosa (Mill.) Urb.) secara empiris dapat digunakan untuk mengobati berbagai penyakit. Umbi bawang dayak diketahui mempunyai senyawa marker golongan naftokuinon yaitu elecanacin, eleutherin, eleutherol dan eleutherinon. Tujuan penelitian ini untuk menganalisis secara kualitatif golongan kuinon dan mengetahui kadar total naftokuinon ekstrak etanol 96% umbi bawang dayak. Metode pengujian kualitatif golongan kuinon menggunakan Kromatografi Lapis Tipis (KLT) dengan fase gerak kloroform:metanol (8:2) dan penampak bercak KOH 10%. Penetapan kadar naftokuinon dilakukan menggunakan spektrofotometer UV-Vis dengan pembanding Lawsone. Hasil KLT menunjukkan terdapat senyawa kuinon yang ditunjukkan dengan terbentuk noda berwarna coklat pada plat KLT. Kadar naftokuinon yaitu 212,345 µgLE/mg. Kesimpulan penelitian yaitu ekstrak etanol 96% umbi bawang dayak terbukti memiliki senyawa naftokuinon.
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