The paper presents the results of investigations of genotoxicity and morphological characteristics of nanoscale gold particles prepared by the electric spark dispersion method in a water medium. To investigate the properties we used comet assay, transmission electron microscopy, thermal desorption of nitrogen (BET). It was revealed, gold particles did not cause DNA damage at low concentrations (0.01 - 0.1 mg/ml) and detectable level of genotoxicity of gold nanoparticles is observed at concentrations of 0.3 mg/ml and above.
Objective: Important trend in the global agribusiness is restrictions of antibiotics content in meat and poultry products. Widespread of antibioticresistant microorganisms leads to huge losses of the effectiveness of the drugs. The aim of the present work was an investigation of the biological activity of antibacterial complex-silver methenamine poultry farming.
Methods:The study of biochemical and hematological indices of blood we performed one day after single and course of oral drug administration on broilers Ross 308. Evaluation of biological action in industrial poultry farming was carried out on a group of 30 thousand broilers after a course of oral administration.Results: revealed the silver complex (in form of water solution) has no toxic effects on blood parameters. It was shown the positive influence on survival and productivity of broilers.
Conclusion:Methenamine silver has certain potential as prospect drug and food additive.
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