This paper reports the results of analysis of human tissue samples collected from Bombay (India). Data on elemental content in twenty tissues/organs collected from twenty cases of instantaneous accidental death of normal adults are presented.The samples were analysed for Na, K, Rb, Ca, Mg,Fe, Mn, Cr, Cu, Zn,Pb, Te andP. All the elements except P were determined by the technique of atomic absorption spectrophotometry. Estimation of P was carried out by the "Molybdenum Blue" method. The statistical treatment of the data obtained is given and the results so obtained are compared with those of ICRP.
In a search for geochemical factors that could play a role in the pathogenesis of tropical endomyocardial fibrosis, endomyocardial tissue samples obtained from patients at necropsy or operation were analysed for major elements present in laterite and monazite, which are important soil constituents of Kerala State of India. Atomic absorption spectrophotometry was used for detecting iron, silicon, aluminium, zinc, magnesium, calcium, sodium, potassium, and manganese and neutron activation analysis for thorium. Compared with control samples from victims of fatal accidents, an excess of thorium, sodium, and calcium and a deficiency of magnesium were present in samples from patients. It has been shown earlier that the staple diets of people in Kerala have high concentrations of thorium, and these data show that thorium can become concentrated in cardiac tissues. It is speculated that thorium excess in conjunction with magnesium deficiency may play a role in the causation of tropical endomyocardial fibrosis.
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