Trace and ultratrace analysis of gallium arsenide by different mass spectrometric techniques

Becker, J. Sabine; Soman, Rajiv S.; Becker, Thomas; Panday, V.K.; Dietze, H.-J.

doi:10.1039/a801525b

Cited by 33 publications

(25 citation statements)

References 9 publications

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“…With its ability to provide very sensitive, accurate and precise multielement determinations of trace elements and of isotope ratios, inductively coupled plasma mass spectrometry (ICP-MS) [7,8,9] has developed into one of the most important inorganic mass spectrometric techniques. One serious disadvantage of ICP-MS, which is the limiting factor of this analytical method, is that a multitude of different isobaric interferences with atomic and molecular ions appear.…”

Section: Introductionmentioning

confidence: 99%

Determination of phosphorus in small amounts of protein samples by ICP–MS

Becker¹,

Boulyga²,

Pickhardt³

et al. 2003

Anal Bioanal Chem

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Inductively coupled plasma mass spectrometry (ICP-MS) is used for phosphorus determination in protein samples. A small amount of solid protein sample (down to 1 micro g) or digest (1-10 micro L) protein solution was denatured in nitric acid and hydrogen peroxide by closed-microvessel microwave digestion. Phosphorus determination was performed with an optimized analytical method using a double-focusing sector field inductively coupled plasma mass spectrometer (ICP-SFMS) and quadrupole-based ICP-MS (ICP-QMS). For quality control of phosphorus determination a certified reference material (CRM), single cell proteins (BCR 273) with a high phosphorus content of 26.8+/-0.4 mg g(-1), was analyzed. For studies on phosphorus determination in proteins while reducing the sample amount as low as possible the homogeneity of CRM BCR 273 was investigated. Relative standard deviation and measurement accuracy in ICP-QMS was within 2%, 3.5%, 11% and 12% when using CRM BCR 273 sample weights of 40 mg, 5 mg, 1 mg and 0.3 mg, respectively. The lowest possible sample weight for an accurate phosphorus analysis in protein samples by ICP-MS is discussed. The analytical method developed was applied for the analysis of homogeneous protein samples in very low amounts [1-100 micro g of solid protein sample, e.g. beta-casein or down to 1 micro L of protein or digest in solution (e.g., tau protein)]. A further reduction of the diluted protein solution volume was achieved by the application of flow injection in ICP-SFMS, which is discussed with reference to real protein digests after protein separation using 2D gel electrophoresis.The detection limits for phosphorus in biological samples were determined by ICP-SFMS down to the ng g(-1) level. The present work discusses the figure of merit for the determination of phosphorus in a small amount of protein sample with ICP-SFMS in comparison to ICP-QMS.

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Section: Introductionmentioning

confidence: 99%

Determination of phosphorus in small amounts of protein samples by ICP–MS

Becker¹,

Boulyga²,

Pickhardt³

et al. 2003

Anal Bioanal Chem

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“…GaAs was analysed using both rf-GD-DFMS and ICP-MS with comparable detection limits, assuming a matrix-separation step is carried out for better quantification with ICP-MS [103]. Furthermore, analysis of trace and ultra-trace elements in a synthetic sample of GaAs (doped with Zn, B, Si, Ge, Sn, Sb, P, S, Se, and Te in the µg g -1 concentration range) by different mass spectrometric techniques including LA-ICP-MS, spark source (SS)-MS, rf-GD-MS and SIMS has been reported more recently [104]. As expected, direct analysis of the solids is a major advantage over ICP-MS, owing to the lower contamination risks and less time-consuming sample preparation steps.…”

Section: Rf-gd-(double Focusing) Msmentioning

confidence: 97%

Radiofrequency glow-discharge devices for direct solid analysis

Pisonero

Costa

Pereiro

et al. 2004

Analytical and Bioanalytical Chemistry

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The enormous potential of radiofrequency glow discharges (rf-GD) as photon, atom, or ion sources, coupled to spectrometric techniques, for rapid direct analysis of almost any conductor, semiconductor, or insulating material with good in-depth resolution has been demonstrated world-wide. This outstanding performance has prompted a great effort to develop and characterise rf-GD for direct materials analysis in recent years. The state of the art of rf-GD coupled to atomic absorption spectrometry, optical emission spectrometry, and mass spectrometry for direct solid analysis is reviewed here. A description of the principles of operation of the rf-GD and attempts to model these discharges are also given. Rf-GD instrumentation, both developed at research laboratories and commercially available, is described. Several practical examples are given demonstrating the capabilities of these techniques for bulk and depth-profile analysis. Finally, the research gaps to be filled for full implementation of rf-GD spectrometric techniques in industry and research centres alike for materials science studies and technical development are discussed.

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“…ICP-MS, TIMS [29][30], AMS [31][32] and RIMS [33][34] are very sensitive mass spectrometric techniques for the determination of ultra trace levels of isotopes, and have been widely used for the determination of ultra-low levels of selected radionuclides and the precise determination of isotopic ratios. Several review articles have addressed the application of mass spectrometric techniques for the determination of radionuclides [2][3][4][5][6][7][8][9]35]. …”

Section: Mass Spectrometrymentioning

confidence: 99%

“…The low abundance sensitivity (or tailing) of ICP-MS is another drawback which limits its application for the determination of radionuclides. Several review articles have addressed the applications and limitations of ICP-MS for the determination of radionuclides [2][3][4][5][6][7][8][9]. Because of the high sensitivity, short analysis time and relatively easy operation, ICP-MS has been widely used for the determination of isotopes of uranium, thorium, and plutonium, 79 Se, 90 Sr, 99 Tc, 129 I, 135 Cs, 210 Pb, 226 Ra, 228 Ra, 231 Pa, 237 Np, 241 Am, 243 Am, and 244 Cm in environmental and waste samples .…”

Section: Inductively Coupled Plasma Mass Spectrometry (Icp-ms)mentioning

confidence: 99%

“…Several informative review articles on the mass spectrometric determination of long-lived radionuclides have been published in recent years [2][3][4][5][6][7][8][9], in which the performance, progress, and interferences of mass spectrometric methods have been discussed in detailed. A few review paper on brief evaluation of radiometric method and mass spectrometry is also available [10].…”

Section: Introductionmentioning

confidence: 99%

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