The first international comparison test on swine lymphocyte alloantigens (SLA) was held in Helsinki, Finland in July 1986. The results reported were based on a comparison of 157 alloantisera originating from six laboratories. The antisera were tested against a selected panel of 264 lymphocyte samples belonging to four laboratories. The most common breeds in Europe were chosen for this first comparison test (Landrace and Large White). Eighteen of the 31 previously known specificities were confirmed and a new nomenclature was established.
SUMMARY
An alloantigen segregating in the double back‐cross families, distinct from serologically determinable transplantation antigens controlled by the major histocompatibility complex (SLA), was detected in pigs by the complementdependent lymphocytotoxic technique. The system was designated SLB and its product (antigen SLB‐Al) was demonstrated in all lymphocytes from the lymph nodes, thymus and peripheral blood, but not in the erythrocytes. Back‐cross matings supplied evidence of the dominant heredity of SLB‐Al. Detection of further SLB antigens was unsuccessful, so that only two alleles (SLB‐Al and SLB‐A‐) could be determined in families. Double back‐cross families revealed a close linkage between the SLB locus and the L blood group locus. Maximum lod score values were calculated in recombination fraction θ= 0.10.
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